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Title
Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants
Authors
Keywords
Mitochondria, Neurons, Neuronal morphology, Superoxides, Parkinson disease, Toxicity, Drosophila melanogaster, Phenotypes
Journal
PLoS Genetics
Volume 9, Issue 4, Pages e1003478
Publisher
Public Library of Science (PLoS)
Online
2013-04-26
DOI
10.1371/journal.pgen.1003478
References
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Related references
Note: Only part of the references are listed.- Silent Information Regulator 2 (Sir2) and Forkhead Box O (FOXO) Complement Mitochondrial Dysfunction and Dopaminergic Neuron Loss inDrosophilaPTEN-induced Kinase 1 (PINK1) Null Mutant
- (2012) Hyongjong Koh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PINK1- and Parkin-mediated mitophagy at a glance
- (2012) Seok Min Jin et al. JOURNAL OF CELL SCIENCE
- PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity
- (2012) Hyongjong Koh et al. MOLECULES AND CELLS
- Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
- (2012) M. Vos et al. SCIENCE
- The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants
- (2012) Sven Vilain et al. PLoS Genetics
- Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins
- (2011) Valerie Uytterhoeven et al. CELL
- Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder
- (2011) Yuzuru Imai et al. CURRENT OPINION IN NEUROBIOLOGY
- The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
- (2011) Wendou Yu et al. HUMAN MOLECULAR GENETICS
- Mitochondrial Dysfunction and Oxidative Stress Contribute to the Pathogenesis of Spinocerebellar Ataxia Type 12 (SCA12)
- (2011) Yu-Chun Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission
- (2011) W. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Interplay Between Mitochondrial Dynamics and Mitophagy
- (2010) Gilad Twig et al. ANTIOXIDANTS & REDOX SIGNALING
- The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
- (2010) Sven Geisler et al. Autophagy
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Genetic Animal Models of Parkinson's Disease
- (2010) Ted M. Dawson et al. NEURON
- Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
- (2010) P. Horak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Roles of PINK1 and Parkin in Parkinson's Disease
- (2010) Rachel Jones PLOS BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
- (2009) Vanessa A. Morais et al. EMBO Molecular Medicine
- A highly reproducible rotenone model of Parkinson's disease
- (2009) Jason R. Cannon et al. NEUROBIOLOGY OF DISEASE
- Tweek, an Evolutionarily Conserved Protein, Is Required for Synaptic Vesicle Recycling
- (2009) Patrik Verstreken et al. NEURON
- Oxidative Inactivation of Mitochondrial Aconitase Results in Iron and H2O2-Mediated Neurotoxicity in Rat Primary Mesencephalic Cultures
- (2009) David Cantu et al. PLoS One
- Iron, the substantia nigra and related neurological disorders
- (2008) Amanda M. Snyder et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
- (2008) C. A. Gautier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
- (2008) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
- (2008) H. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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