Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells
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Title
Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells
Authors
Keywords
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Journal
JOURNAL OF BONE AND MINERAL RESEARCH
Volume 33, Issue 2, Pages 338-355
Publisher
Wiley
Online
2017-09-23
DOI
10.1002/jbmr.3293
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- (2016) Shuai Chen et al. LABORATORY INVESTIGATION
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- (2016) Kaori Suyama et al. Oncotarget
- Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target
- (2016) Hamish T. J. Gilbert et al. Scientific Reports
- The contributions of respiration and glycolysis to extracellular acid production
- (2015) Shona A. Mookerjee et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Defining the phenotype of young healthy nucleus pulposus cells: Recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting
- (2015) Makarand V. Risbud et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles
- (2015) Anthony Mathelier et al. NUCLEIC ACIDS RESEARCH
- Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function
- (2015) Somayeh Jamali et al. Scientific Reports
- Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation
- (2014) Ting-Hsien Kao et al. JOURNAL OF NEUROSURGERY-SPINE
- Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: Evolving role of TonEBP
- (2014) Zariel I. Johnson et al. MATRIX BIOLOGY
- Loss of HIF-1α in the Notochord Results in Cell Death and Complete Disappearance of the Nucleus Pulposus
- (2014) Christophe Merceron et al. PLoS One
- MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
- (2013) György Csordás et al. Cell Metabolism
- The State of US Health, 1990-2010
- (2013) Christopher J. L. Murray JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Hypoxia-inducible Factor (HIF)-1α and CCN2 Form a Regulatory Circuit in Hypoxic Nucleus Pulposus Cells
- (2013) Cassie M. Tran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes
- (2013) Dessislava Z Markova et al. ARTHRITIS RESEARCH & THERAPY
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- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: Role of Hsp70 in HIF-1α degradation
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- Lactate flux in astrocytes is enhanced by a non-catalytic action of carbonic anhydrase II
- (2012) Malin H. Stridh et al. JOURNAL OF PHYSIOLOGY-LONDON
- Identification of cell surface-specific markers to target human nucleus pulposus cells: Expression of carbonic anhydrase XII varies with age and degeneration
- (2011) Karen A. Power et al. ARTHRITIS AND RHEUMATISM
- HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
- (2011) Nobuyuki Fujita et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
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- Carbonic anhydrase inhibitors
- (2010) Claudiu T. Supuran BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- New insights into the physiological role of carbonic anhydrase IX in tumour pH regulation
- (2010) P Swietach et al. ONCOGENE
- Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits
- (2010) Takashi Miyamoto et al. ARTHRITIS RESEARCH & THERAPY
- Modular structure of sodium-coupled bicarbonate transporters
- (2009) W. F. Boron et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Sensors and regulators of intracellular pH
- (2009) Joseph R. Casey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bicarbonate transport in cell physiology and disease
- (2008) Emmanuelle Cordat et al. BIOCHEMICAL JOURNAL
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- (2008) J. Chiche et al. CANCER RESEARCH
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