Insights into the catalysis of a lysine-tryptophan bond in bacterial peptides by a SPASM domain radical S -adenosylmethionine (SAM) peptide cyclase

Post-translational modification of ribosomally synthesized peptides by a radical SAM epimerase in Bacillus subtilis

(2017) Alhosna Benjdia et al.   Nature Chemistry

DNA Repair by the Radical SAM Enzyme Spore Photoproduct Lyase: From Biochemistry to Structural Investigations

(2017) Olivier Berteau et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Sulfatases and radical SAM enzymes: emerging themes in glycosaminoglycan metabolism and the human microbiota

(2016) A. Benjdia et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Radical S-Adenosyl-l-methionine Enzyme MftC Catalyzes an Oxidative Decarboxylation of the C-Terminus of the MftA Peptide

(2016) Nathan A. Bruender et al.   BIOCHEMISTRY

Thioether bond formation by SPASM domain radical SAM enzymes: Cα H-atom abstraction in subtilosin A biosynthesis

(2016) Alhosna Benjdia et al.   CHEMICAL COMMUNICATIONS

Demonstration That the RadicalS-Adenosylmethionine (SAM) Enzyme PqqE Catalyzesde NovoCarbon-Carbon Cross-linking within a Peptide Substrate PqqA in the Presence of the Peptide Chaperone PqqD

(2016) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The B12-Radical SAM Enzyme PoyC Catalyzes Valine Cβ-Methylation during Polytheonamide Biosynthesis

(2016) Aubérie Parent et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystallographic snapshots of sulfur insertion by lipoyl synthase

(2016) Martin I. McLaughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RadicalS-Adenosyl-l-methionine Enzyme QhpD Catalyzes Sequential Formation of Intra-protein Sulfur-to-Methylene Carbon Thioether Bonds

(2015) Tadashi Nakai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink

(2015) Kelsey R. Schramma et al.   Nature Chemistry

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

The thiostrepton A tryptophan methyltransferase TsrM catalyses a cob(II)alamin-dependent methyl transfer reaction

(2015) Alhosna Benjdia et al.   Nature Communications

Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions

(2014) Jenny E. Harmer et al.   BIOCHEMICAL JOURNAL

Radical S-Adenosylmethionine Enzymes

(2014) Joan B. Broderick et al.   CHEMICAL REVIEWS

RadicalS-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

(2014) Angad P. Mehta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SPASM and Twitch Domains inS-Adenosylmethionine (SAM) Radical Enzymes

(2014) Tsehai A. J. Grell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A conserved lysine residue controls iron–sulfur cluster redox chemistry in Escherichia coli fumarate reductase

(2013) Victor W.T. Cheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Two [4Fe-4S] Clusters Containing Radical SAM Enzyme SkfB Catalyze Thioether Bond Formation during the Maturation of the Sporulation Killing Factor

(2013) Leif Flühe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

(2013) P. J. Goldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes

(2012) Stéphane Pierre et al.   Nature Chemical Biology

The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

(2012) Leif Flühe et al.   Nature Chemical Biology

Biological Systems Discovery In Silico: Radical S-Adenosylmethionine Protein Families and Their Target Peptides for Posttranslational Modification

(2011) D. H. Haft et al.   JOURNAL OF BACTERIOLOGY

Sulfatases and a RadicalS-Adenosyl-l-methionine (AdoMet) Enzyme Are Key for Mucosal Foraging and Fitness of the Prominent Human Gut Symbiont,Bacteroides thetaiotaomicron

(2011) Alhosna Benjdia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural, mechanistic and coordination chemistry of relevance to the biosynthesis of iron–sulfur and related iron cofactors☆

(2010) Wenbin Qi et al.   COORDINATION CHEMISTRY REVIEWS

Anaerobic sulfatase-maturating enzyme - A mechanistic link with glycyl radical-activating enzymes?

(2010) Alhosna Benjdia et al.   FEBS Journal

Histidine 103 in Fra2 Is an Iron-Sulfur Cluster Ligand in the [2Fe-2S] Fra2-Grx3 Complex and Is Required forin VivoIron Signaling in Yeast

(2010) Haoran Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyrroloquinoline Quinone Biogenesis: Demonstration That PqqE fromKlebsiella pneumoniaeIs a RadicalS-Adenosyl-l-methionine Enzyme

(2009) Stephen R. Wecksler et al.   BIOCHEMISTRY

Mechanistic Investigations of Anaerobic Sulfatase-Maturating Enzyme: Direct CβH-Atom Abstraction Catalyzed by a Radical AdoMet Enzyme

(2009) Alhosna Benjdia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anaerobic Sulfatase-maturating Enzymes, First Dual Substrate RadicalS-Adenosylmethionine Enzymes

(2008) Alhosna Benjdia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY