RadicalS-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

Paramagnetic Intermediates Generated by Radical S-Adenosylmethionine (SAM) Enzymes

(2014) Troy A. Stich et al.   ACCOUNTS OF CHEMICAL RESEARCH

Crystal Structure of Tryptophan Lyase (NosL): Evidence for Radical Formation at the Amino Group of Tryptophan

(2014) Yvain Nicolet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical S-Adenosylmethionine Enzymes

(2014) Joan B. Broderick et al.   CHEMICAL REVIEWS

The Biosynthesis of Thiol- and Thioether-containing Cofactors and Secondary Metabolites Catalyzed by RadicalS-Adenosylmethionine Enzymes

(2014) Joseph T. Jarrett   JOURNAL OF BIOLOGICAL CHEMISTRY

Molybdopterin Biosynthesis: Trapping of Intermediates for the MoaA-Catalyzed Reaction Using 2′-DeoxyGTP and 2′-ChloroGTP as Substrate Analogues.

(2014) Angad P. Mehta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The HydG Enzyme Generates an Fe(CO)2(CN) Synthon in Assembly of the FeFe Hydrogenase H-Cluster

(2014) J. M. Kuchenreuther et al.   SCIENCE

In Vitro Reconstitution of the Radical S-Adenosylmethionine Enzyme MqnC Involved in the Biosynthesis of Futalosine-Derived Menaquinone

(2013) Lisa E. Cooper et al.   BIOCHEMISTRY

Catalysis of a New Ribose Carbon-Insertion Reaction by the Molybdenum Cofactor Biosynthetic Enzyme MoaA

(2013) Angad P. Mehta et al.   BIOCHEMISTRY

Molybdopterin Biosynthesis: Trapping an Unusual Purine Ribose Adduct in the MoaA-Catalyzed Reaction

(2013) Angad P. Mehta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme

(2013) Nilkamal Mahanta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of a Cyclic Nucleotide as a Cryptic Intermediate in Molybdenum Cofactor Biosynthesis

(2013) Bradley M. Hover et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biosynthesis of F0, Precursor of the F420 Cofactor, Requires a Unique Two Radical-SAM Domain Enzyme and Tyrosine as Substrate

(2012) Laure Decamps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into Radical Generation by the Radical SAM Superfamily

(2011) Jessica L. Vey et al.   CHEMICAL REVIEWS

Radical O→C Transposition: A Metal-Free Process for Conversion of Phenols into Benzoates and Benzamides

(2011) Abdulkader Baroudi et al.   JOURNAL OF ORGANIC CHEMISTRY

Convergent strategies in biosynthesis

(2011) Tohru Dairi et al.   NATURAL PRODUCT REPORTS

Radical-mediated enzymatic carbon chain fragmentation-recombination

(2011) Qi Zhang et al.   Nature Chemical Biology

A “Radical Dance” in Thiamin Biosynthesis: Mechanistic Analysis of the Bacterial Hydroxymethylpyrimidine Phosphate Synthase

(2010) Abhishek Chatterjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Free Transformation of Phenols into Substituted Benzamides: A Highly Selective Radical 1,2-O→C Transposition in O-Aryl-N-phenylthiocarbamates

(2010) Abdulkader Baroudi et al.   CHEMISTRY-A EUROPEAN JOURNAL

The history of the discovery of the molybdenum cofactor and novel aspects of its biosynthesis in bacteria

(2010) Silke Leimkühler et al.   COORDINATION CHEMISTRY REVIEWS

Radicals from S-adenosylmethionine and their application to biosynthesis

(2010) Peter L Roach   CURRENT OPINION IN CHEMICAL BIOLOGY

Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme

(2010) Yang Zhang et al.   NATURE

The O-neophyl rearrangement of 1,1-diarylalkoxyl radicals. Experimental evidence for the formation of an intermediate 1-oxaspiro[2,5]octadienyl radical

(2010) Massimo Bietti et al.   TETRAHEDRON LETTERS

Catalytic Activity of the Anaerobic Tyrosine Lyase Required for Thiamine Biosynthesis in Escherichia coli

(2009) Martin R. Challand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ENDOR Spectroscopy Shows That Guanine N1 Binds to [4Fe−4S] Cluster II of theS-Adenosylmethionine-Dependent Enzyme MoaA: Mechanistic Implications

(2009) Nicholas S. Lees et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Studies on A New Biosynthetic Pathway for Menaquinone

(2008) Haruo Seto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

(2008) Abhishek Chatterjee et al.   Nature Chemical Biology

An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms

(2008) T. Hiratsuka et al.   SCIENCE