Thioether bond formation by SPASM domain radical SAM enzymes: Cα H-atom abstraction in subtilosin A biosynthesis

The PqqD homologous domain of the radical SAM enzyme ThnB is required for thioether bond formation during thurincin H maturation

(2015) Beata M. Wieckowski et al.   FEBS LETTERS

Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis

(2015) Benjamin Philmus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions

(2014) Jenny E. Harmer et al.   BIOCHEMICAL JOURNAL

SPASM and Twitch Domains inS-Adenosylmethionine (SAM) Radical Enzymes

(2014) Tsehai A. J. Grell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate control in stereoselective lanthionine biosynthesis

(2014) Weixin Tang et al.   Nature Chemistry

Two [4Fe-4S] Clusters Containing Radical SAM Enzyme SkfB Catalyze Thioether Bond Formation during the Maturation of the Sporulation Killing Factor

(2013) Leif Flühe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

(2013) P. J. Goldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biosynthesis of F0, Precursor of the F420 Cofactor, Requires a Unique Two Radical-SAM Domain Enzyme and Tyrosine as Substrate

(2012) Laure Decamps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

(2012) Leif Flühe et al.   Nature Chemical Biology

Dissociation energies of X–H bonds in amino acids

(2012) Benjamin N. Moore et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Anaerobic sulfatase-maturating enzyme - A mechanistic link with glycyl radical-activating enzymes?

(2010) Alhosna Benjdia et al.   FEBS Journal

Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

(2010) M. C. Rea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic Investigations of Anaerobic Sulfatase-Maturating Enzyme: Direct CβH-Atom Abstraction Catalyzed by a Radical AdoMet Enzyme

(2009) Alhosna Benjdia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anaerobic Sulfatase-maturating Enzymes, First Dual Substrate RadicalS-Adenosylmethionine Enzymes

(2008) Alhosna Benjdia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY