Serotype-specific interactions among functional domains of dengue virus 2 nonstructural proteins (NS) 5 and NS3 are crucial for viral RNA replication

Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface

(2016) Valerie J. Klema et al.   PLoS Pathogens

The dengue virus NS5 protein as a target for drug discovery

(2015) Siew Pheng Lim et al.   ANTIVIRAL RESEARCH

Flexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication

(2015) Yongqian Zhao et al.   JOURNAL OF VIROLOGY

Dengue

(2015) Maria G Guzman et al.   LANCET

Flavivirus RNA synthesis in vitro

(2015) Radhakrishnan Padmanabhan et al.   METHODS

Oxidative stress influences positive strand RNA virus genome synthesis and capping

(2015) Rebekah C. Gullberg et al.   VIROLOGY

A Crystal Structure of the Dengue Virus NS5 Protein Reveals a Novel Inter-domain Interface Essential for Protein Flexibility and Virus Replication

(2015) Yongqian Zhao et al.   PLoS Pathogens

RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence

(2014) Victoria K. Korboukh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substitution of NS5 N-terminal Domain of Dengue Virus Type 2 RNA with Type 4 Domain Caused Impaired Replication and Emergence of Adaptive Mutants with Enhanced Fitness

(2014) Tadahisa Teramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flavivirus RNA methylation

(2014) H. Dong et al.   JOURNAL OF GENERAL VIROLOGY

Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA

(2014) Leopoldo G. Gebhard et al.   NUCLEIC ACIDS RESEARCH

A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability andde NovoInitiation Activities

(2013) Siew Pheng Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein

(2013) C. S. E. Tan et al.   JOURNAL OF GENERAL VIROLOGY

The role of mutational robustness in RNA virus evolution

(2013) Adam S. Lauring et al.   NATURE REVIEWS MICROBIOLOGY

Protein–protein interactions among West Nile non-structural proteins and transmembrane complex formation in mammalian cells

(2013) Li Yu et al.   VIROLOGY

Viral Quasispecies Evolution

(2012) E. Domingo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Novel ATP-Independent RNA Annealing Activity of the Dengue Virus NS3 Helicase

(2012) Leopoldo G. Gebhard et al.   PLoS One

Secondary heterologous dengue infection risk: Disequilibrium between immune regulation and inflammation?

(2010) Beatriz Sierra et al.   CELLULAR IMMUNOLOGY

Flexibility between the Protease and Helicase Domains of the Dengue Virus NS3 Protein Conferred by the Linker Region and Its Functional Implications

(2010) Dahai Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotype-Specific Differences in the Risk of Dengue Hemorrhagic Fever: An Analysis of Data Collected in Bangkok, Thailand from 1994 to 2006

(2010) Jessica R. Fried et al.   PLoS Neglected Tropical Diseases

Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites

(2009) Sonja Welsch et al.   Cell Host & Microbe

The quasispecies nature and biological implications of the hepatitis C virus

(2009) Sarah L. Fishman et al.   INFECTION GENETICS AND EVOLUTION

Structural proteomics of dengue virus

(2008) Rushika Perera et al.   CURRENT OPINION IN MICROBIOLOGY

Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNA

(2008) B. Zhang et al.   JOURNAL OF VIROLOGY