Can Better Management of Periodontal Disease Delay the Onset and Progression of Alzheimer’s Disease?

Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression

(2017) Osamu Itani et al.   SLEEP MEDICINE

Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease

(2017) Jonathan Cedernaes et al.   SLEEP MEDICINE REVIEWS

Chronic Porphyromonas gingivalis infection accelerates the occurrence of age-related granules in ApoE–/– mice brains

(2017) Sim K. Singhrao et al.   Journal of Oral Microbiology

Chlamydophila Pneumoniae and the Etiology of Late-Onset Alzheimer's Disease

(2017) Brian J. Balin et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammasome Involvement in Alzheimer’s Disease

(2016) Ingar Olsen et al.   JOURNAL OF ALZHEIMERS DISEASE

Bacterial Amyloid and DNA are Important Constituents of Senile Plaques: Further Evidence of the Spirochetal and Biofilm Nature of Senile Plaques

(2016) Judith Miklossy   JOURNAL OF ALZHEIMERS DISEASE

Apolipoprotein E Related Co-Morbidities and Alzheimer’s Disease

(2016) Sim K. Singhrao et al.   JOURNAL OF ALZHEIMERS DISEASE

Gram-negative bacterial molecules associate with Alzheimer disease pathology

(2016) Xinhua Zhan et al.   NEUROLOGY

The effects of weight loss approaches on bone mineral density in adults: a systematic review and meta-analysis of randomized controlled trials

(2016) S. Soltani et al.   OSTEOPOROSIS INTERNATIONAL

The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

(2016) Samuel E. Marsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms linking circadian clocks, sleep, and neurodegeneration

(2016) Erik S. Musiek et al.   SCIENCE

Risk factors for sleep disturbances in older adults: Evidence from prospective studies

(2016) Stephen F. Smagula et al.   SLEEP MEDICINE REVIEWS

Sleep: A Novel Mechanistic Pathway, Biomarker, and Treatment Target in the Pathology of Alzheimer's Disease?

(2016) Bryce A. Mander et al.   TRENDS IN NEUROSCIENCES

Periodontitis and Cognitive Decline in Alzheimer’s Disease

(2016) Mark Ide et al.   PLoS One

Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system

(2016) Fumiko Takayama et al.   Scientific Reports

Self-reported sleep disturbance is associated with Alzheimer's disease risk in men

(2015) Christian Benedict et al.   Alzheimers & Dementia

Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective

(2015) Matthew Baumgart et al.   Alzheimers & Dementia

Why Sleep Is Important for Health: A Psychoneuroimmunology Perspective

(2015) Michael R. Irwin   Annual Review of Psychology

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

(2015) Sandra I. Mota et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cortical Development, Electroencephalogram Rhythms, and the Sleep/Wake Cycle

(2015) Chiara Cirelli et al.   BIOLOGICAL PSYCHIATRY

Sleep and immunity: A growing field with clinical impact

(2015) Mark R. Opp et al.   BRAIN BEHAVIOR AND IMMUNITY

Accelerated pericyte degeneration and blood–brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer’s disease

(2015) Matthew R Halliday et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sleep as a biological problem: an overview of frontiers in sleep research

(2015) Takeshi Kanda et al.   Journal of Physiological Sciences

Periodontal disease associates with higher brain amyloid load in normal elderly

(2015) Angela R. Kamer et al.   NEUROBIOLOGY OF AGING

The Glymphatic System: A Beginner’s Guide

(2015) Nadia Aalling Jessen et al.   NEUROCHEMICAL RESEARCH

Porphyromonas gingivalisvirulence factors involved in subversion of leukocytes and microbial dysbiosis

(2015) Camille Zenobia et al.   Virulence

Historic evidence to support a causal relationship between spirochetal infections and Alzheimer’s disease

(2015) Judith Miklossy   Frontiers in Aging Neuroscience

Vascular Plasticity and Cognition During Normal Aging and Dementia

(2015) Axel Montagne et al.   JAMA Neurology

Can oral infection be a risk factor for Alzheimer's disease?

(2015) Ingar Olsen et al.   Journal of Oral Microbiology

Evaluation of patients with Alzheimer's disease before and after dental treatment

(2014) Thaís de Souza Rolim et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Self-Reported Head Injury and Risk of Late-Life Impairment and AD Pathology in an AD Center Cohort

(2014) Erin L. Abner et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

(2014) Jeffrey J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Active Invasion of Oral and Aortic Tissues by Porphyromonas gingivalis in Mice Causally Links Periodontitis and Atherosclerosis

(2014) Irina M. Velsko et al.   PLoS One

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

(2014) N. M. Moutsopoulos et al.   Science Translational Medicine

Poor Oral Health as a Chronic, Potentially Modifiable Dementia Risk Factor: Review of the Literature

(2013) James M. Noble et al.   Current Neurology and Neuroscience Reports

Sleep loss and circadian disruption in shift work: health burden and management

(2013) Shantha M W Rajaratnam et al.   MEDICAL JOURNAL OF AUSTRALIA

Garbage Truck of the Brain

(2013) M. Nedergaard   SCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons

(2013) Andrew S. P. Lim et al.   SLEEP

Sleep Quality and Preclinical Alzheimer Disease

(2013) Yo-El S. Ju et al.   JAMA Neurology

Reciprocal interactions between sleep, circadian rhythms and Alzheimer's disease: Focus on the role of hypocretin and melatonin

(2012) Diane Slats et al.   AGEING RESEARCH REVIEWS

Serum antibodies to periodontal pathogens are a risk factor for Alzheimer’s disease

(2012) Pamela Sparks Stein et al.   Alzheimers & Dementia

Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?

(2012) Peter B. Lockhart et al.   CIRCULATION

Dentition, Dental Health Habits, and Dementia: The Leisure World Cohort Study

(2012) Annlia Paganini-Hill et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Sleep: A Health Imperative

(2012) Faith S. Luyster et al.   SLEEP

Changes in sleep theta rhythm are related to episodic memory impairment in early Alzheimer's disease

(2011) Pascal Hot et al.   BIOLOGICAL PSYCHOLOGY

Insulin resistance and Alzheimer's disease

(2011) Suzanne M. De La Monte   BMB Reports

Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies

(2011) Francesco P. Cappuccio et al.   EUROPEAN HEART JOURNAL

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria

(2011) Judith Miklossy   Journal of Neuroinflammation

Sleep and Sleep Disorders in Older Adults

(2011) Kate Crowley   NEUROPSYCHOLOGY REVIEW

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Inflammation as a potential mediator for the association between periodontal disease and Alzheimer’s disease

(2011) Amber Watts et al.   Neuropsychiatric Disease and Treatment

Tooth Loss, Apolipoprotein E, and Decline in Delayed Word Recall

(2010) P.S. Stein et al.   JOURNAL OF DENTAL RESEARCH

Tooth Loss and Periodontal Disease Predict Poor Cognitive Function in Older Men

(2010) Elizabeth Krall Kaye et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease

(2010) Katharina Wulff et al.   NATURE REVIEWS NEUROSCIENCE

Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids

(2010) Rebecca Wall et al.   NUTRITION REVIEWS

Inflammation, Cytokines, Immune Response, Apolipoprotein E, Cholesterol, and Oxidative Stress in Alzheimer Disease: Therapeutic Implications

(2010) Giuseppina Candore et al.   REJUVENATION RESEARCH

Alzheimer's disease and infection: Do infectious agents contribute to progression of Alzheimer's disease?

(2009) Kie Honjo et al.   Alzheimers & Dementia

Modulating human aging and age-associated diseases

(2009) Luigi Fontana   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Quantity and Quality of Sleep and Incidence of Type 2 Diabetes: A systematic review and meta-analysis

(2009) F. P. Cappuccio et al.   DIABETES CARE

TNF-α and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects

(2009) Angela R. Kamer et al.   JOURNAL OF NEUROIMMUNOLOGY

Periodontitis is associated with cognitive impairment among older adults: analysis of NHANES-III

(2009) J M Noble et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Effects of poor and short sleep on glucose metabolism and obesity risk

(2009) Karine Spiegel et al.   Nature Reviews Endocrinology

Systemic inflammation and disease progression in Alzheimer disease

(2009) C. Holmes et al.   NEUROLOGY

Is Sleep Essential?

(2008) Chiara Cirelli et al.   PLOS BIOLOGY

Inflammation and Alzheimer's disease: Possible role of periodontal diseases

(2007) Angela R. Kamer et al.   Alzheimers & Dementia