Porphyromonas gingivalisvirulence factors involved in subversion of leukocytes and microbial dysbiosis

Polymicrobial synergy and dysbiosis in inflammatory disease

(2015) Richard J. Lamont et al.   TRENDS IN MOLECULAR MEDICINE

Role of Porphyromonas gingivalis gingipains in multi-species biofilm formation

(2014) Kai Bao et al.   BMC MICROBIOLOGY

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Porphyromonas gingivalis Manipulates Complement and TLR Signaling to Uncouple Bacterial Clearance from Inflammation and Promote Dysbiosis

(2014) Tomoki Maekawa et al.   Cell Host & Microbe

The oral microbiome and the immunobiology of periodontal disease and caries

(2014) Massimo Costalonga et al.   IMMUNOLOGY LETTERS

The Role of Oral Pathobionts in Dysbiosis during Periodontitis Development

(2014) Y. Jiao et al.   JOURNAL OF DENTAL RESEARCH

Binding of Complement Inhibitor C4b-Binding Protein Contributes to Serum Resistance of Porphyromonas gingivalis

(2014) M. Potempa et al.   JOURNAL OF IMMUNOLOGY

Inefficient star formation in extremely metal poor galaxies

(2014) Yong Shi et al.   NATURE

Defective Neutrophil Recruitment in Leukocyte Adhesion Deficiency Type I Disease Causes Local IL-17-Driven Inflammatory Bone Loss

(2014) N. M. Moutsopoulos et al.   Science Translational Medicine

Porphyromonas gingivalis neutrophil manipulation: risk factor for periodontitis?

(2014) Richard P. Darveau   TRENDS IN MICROBIOLOGY

Metatranscriptomics of the Human Oral Microbiome during Health and Disease

(2014) P. Jorth et al.   mBio

Distinct Lipid A Moieties Contribute to Pathogen-Induced Site-Specific Vascular Inflammation

(2014) Connie Slocum et al.   PLoS Pathogens

Historical and contemporary hypotheses on the development of oral diseases: are we there yet?

(2014) Bob T. Rosier et al.   Frontiers in Cellular and Infection Microbiology

Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis

(2013) Camille Zenobia et al.   CELLULAR MICROBIOLOGY

Breaking bad: Manipulation of the host response byPorphyromonas gingivalis

(2013) George Hajishengallis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Exploring the genetic basis of chronic periodontitis: a genome-wide association study

(2013) K. Divaris et al.   HUMAN MOLECULAR GENETICS

Porphyromonas gingivalis Lipid A Phosphatase Activity Is Critical for Colonization and Increasing the Commensal Load in the Rabbit Ligature Model

(2013) Camille Zenobia et al.   INFECTION AND IMMUNITY

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation

(2013) Loreto Abusleme et al.   ISME Journal

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response

(2013) George Hajishengallis   TRENDS IN IMMUNOLOGY

The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65

(2013) Hiroki Takeuchi et al.   PLoS Pathogens

Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)

(2013) Katarzyna J. Maresz et al.   PLoS Pathogens

Porphyromonas gingivalis-nucleoside-diphosphate-kinase inhibits ATP-induced reactive-oxygen-species via P2X7receptor/NADPH-oxidase signalling and contributes to persistence

(2012) Chul Hee Choi et al.   CELLULAR MICROBIOLOGY

Porphyromonas gingivalis: an invasive and evasive opportunistic oral pathogen

(2012) Nagihan Bostanci et al.   FEMS MICROBIOLOGY LETTERS

Smoking and the subgingival ecosystem: a pathogen-enriched community

(2012) Purnima S Kumar   Future Microbiology

Disruption of immune regulation by microbial pathogens and resulting chronic inflammation

(2012) Kenneth Barth et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Porphyromonas gingivalis as a Potential Community Activist for Disease

(2012) R.P. Darveau et al.   JOURNAL OF DENTAL RESEARCH

Local Complement-Targeted Intervention in Periodontitis: Proof-of-Concept Using a C5a Receptor (CD88) Antagonist

(2012) T. Abe et al.   JOURNAL OF IMMUNOLOGY

Microbial Carriage State of Peripheral Blood Dendritic Cells (DCs) in Chronic Periodontitis Influences DC Differentiation, Atherogenic Potential

(2012) J. Carrion et al.   JOURNAL OF IMMUNOLOGY

Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to Porphyromonas gingivalis

(2012) Dalia E. Gaddis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

Mechanism and implications of CXCR4-mediated integrin activation byPorphyromonas gingivalis

(2012) G. Hajishengallis et al.   Molecular Oral Microbiology

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Oral Inflammatory Diseases and Systemic Inflammation: Role of the Macrophage

(2012) Hatice Hasturk et al.   Frontiers in Immunology

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Temperature-Dependent Modulation ofPorphyromonas gingivalisLipid A Structure and Interaction with the Innate Host Defenses

(2011) Michael A. Curtis et al.   INFECTION AND IMMUNITY

How has neutrophil research improved our understanding of periodontal pathogenesis?

(2011) Gabriel Nussbaum et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Genetic susceptibility to periodontitis

(2011) Marja L. Laine et al.   PERIODONTOLOGY 2000

Signaling mechanisms in the restoration of impaired immune function due to diet-induced obesity

(2011) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis

(2010) Natalia Wegner et al.   ARTHRITIS AND RHEUMATISM

Role of Porphyromonas gingivalis Phosphoserine Phosphatase Enzyme SerB in Inflammation, Immune Response, and Induction of Alveolar Bone Resorption in Rats

(2010) B. Bainbridge et al.   INFECTION AND IMMUNITY

The Native 67-Kilodalton Minor Fimbria of Porphyromonas gingivalis Is a Novel Glycoprotein with DC-SIGN-Targeting Motifs

(2010) A. E. Zeituni et al.   JOURNAL OF BACTERIOLOGY

The Human Oral Microbiome

(2010) F. E. Dewhirst et al.   JOURNAL OF BACTERIOLOGY

Destructive and Protective Roles of Cytokines in Periodontitis: A Re-appraisal from Host Defense and Tissue Destruction Viewpoints

(2010) G.P. Garlet   JOURNAL OF DENTAL RESEARCH

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

Porphyromonas gingivalis cell-induced hemagglutination and platelet aggregation

(2010) Koji Nakayama   PERIODONTOLOGY 2000

Comparison of neutrophil functions in aggressive and chronic periodontitis

(2010) Mark I. Ryder   PERIODONTOLOGY 2000

Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon’s knife to a meat chopper-like brutal degradation of proteins

(2010) Yonghua Guo et al.   PERIODONTOLOGY 2000

Genetic and environmental risk factors for chronic periodontitis and aggressive periodontitis

(2010) Ayala Stabholz et al.   PERIODONTOLOGY 2000

Human Toll-like receptor 4 responses toP. gingivalisare regulated by lipid A 1- and 4′-phosphatase activities

(2009) Stephen R. Coats et al.   CELLULAR MICROBIOLOGY

The Oral Microbial Consortium's Interaction with the Periodontal Innate Defense System

(2009) Richard P. Darveau   DNA AND CELL BIOLOGY

Tobacco-induced alterations toPorphyromonas gingivalis-host interactions

(2009) Juhi Bagaitkar et al.   ENVIRONMENTAL MICROBIOLOGY

A New Inflammatory Cytokine on the Block: Re-thinking Periodontal Disease and the Th1/Th2 Paradigm in the Context of Th17 Cells and IL-17

(2009) S.L. Gaffen et al.   JOURNAL OF DENTAL RESEARCH

Targeting of DC-SIGN on Human Dendritic Cells by Minor Fimbriated Porphyromonas gingivalis Strains Elicits a Distinct Effector T Cell Response

(2009) A. E. Zeituni et al.   JOURNAL OF IMMUNOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Porphyromonas gingivalismediates the shedding and proteolysis of complement regulatory protein CD46 expressed by oral epithelial cells

(2009) H. Mahtout et al.   Oral microbiology and immunology

Interpain A, a Cysteine Proteinase from Prevotella intermedia, Inhibits Complement by Degrading Complement Factor C3

(2009) Michal Potempa et al.   PLoS Pathogens

ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis

(2008) Özlem Yilmaz et al.   CELLULAR MICROBIOLOGY

Lipid raft-dependent uptake, signalling and intracellular fate ofPorphyromonas gingivalisin mouse macrophages

(2008) Min Wang et al.   CELLULAR MICROBIOLOGY

The chronicles of Porphyromonas gingivalis: the microbium, the human oral epithelium and their interplay

(2008) O. Yilmaz   MICROBIOLOGY-SGM

Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function

(2008) G. Hajishengallis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA