proBDNF Accelerates Brain Amyloid-β Deposition and Learning and Memory Impairment in APPswePS1dE9 Transgenic Mice

Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease

(2015) Robert Baranello et al.   Current Alzheimer Research

p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer’s disease

(2015) X-Q Yao et al.   MOLECULAR PSYCHIATRY

proBDNF Attenuates Hippocampal Neurogenesis and Induces Learning and Memory Deficits in Aged Mice

(2015) Jia Chen et al.   NEUROTOXICITY RESEARCH

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Alzheimer's disease under strain

(2014) Adriano Aguzzi   NATURE

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

(2014) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Evidences for B6C3-Tg (APPswe/PSEN1dE9) Double-Transgenic Mice Between 3 and 10 Months as an Age-Related Alzheimer’s Disease Model

(2013) Zhiyong Zhong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

ProBDNF and Mature BDNF as Punishment and Reward Signals for Synapse Elimination at Mouse Neuromuscular Junctions

(2013) H. S. Je et al.   JOURNAL OF NEUROSCIENCE

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

(2013) Victor L Villemagne et al.   LANCET NEUROLOGY

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro

(2013) J. Xiong et al.   NEURO-ONCOLOGY

Mechanisms underlying synaptic vulnerability and degeneration in neurodegenerative disease

(2013) T. H. Gillingwater et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?

(2013) Jens Moreth et al.   Immunity & Ageing

Serum Brain-Derived Neurotrophic Factor and the Risk for Dementia

(2013) Galit Weinstein et al.   JAMA Neurology

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Deciphering the mechanism underlying late-onset Alzheimer disease

(2012) Dimitrije Krstic et al.   Nature Reviews Neurology

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

(2012) Ying Sun et al.   PLoS One

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice

(2011) Zhi-Qiang Xu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons

(2010) Hisatsugu Koshimizu et al.   NEUROSCIENCE LETTERS

Neuronal release of proBDNF

(2009) Jianmin Yang et al.   NATURE NEUROSCIENCE

Whither proBDNF?

(2009) Philip A Barker   NATURE NEUROSCIENCE

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Effects of proNGF on Neuronal Viability, Neurite Growth and Amyloid-beta Metabolism

(2009) Yan-Jiang Wang et al.   NEUROTOXICITY RESEARCH

Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats

(2008) Yong-jun Fan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE