p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer’s disease

Lessons from immunotherapy for Alzheimer disease

(2014) Yan-Jiang Wang   Nature Reviews Neurology

ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice

(2013) C Tiveron et al.   CELL DEATH AND DIFFERENTIATION

Amyloid beta1-42(Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway

(2013) Khalil Saadipour et al.   JOURNAL OF NEUROCHEMISTRY

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases

(2013) Mathéa Pietri et al.   NATURE MEDICINE

Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress

(2012) Rudy J. Castellani et al.   ARCHIVES OF MEDICAL RESEARCH

Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations

(2012) Linda Chami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nerve Growth Factor and Alzheimer's Disease: New Facts for an Old Hypothesis

(2012) Antonino Cattaneo et al.   MOLECULAR NEUROBIOLOGY

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

(2012) Carlos F. Ibáñez et al.   TRENDS IN NEUROSCIENCES

Roles of p75NTR in the pathogenesis of Alzheimer's disease: A novel therapeutic target

(2011) Fan Zeng et al.   BIOCHEMICAL PHARMACOLOGY

Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling

(2011) Reddy P. Kommaddi et al.   FASEB JOURNAL

Nogo-66 inhibits adhesion and migration of microglia via GTPase Rho pathway in vitro

(2011) Jun Yan et al.   JOURNAL OF NEUROCHEMISTRY

p75NTR Regulates A  Deposition by Increasing A  Production But Inhibiting A  Aggregation with Its Extracellular Domain

(2011) Y.-J. Wang et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

(2010) S. Capsoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

(2009) C. W. Christine et al.   NEUROLOGY

Effects of proNGF on Neuronal Viability, Neurite Growth and Amyloid-beta Metabolism

(2009) Yan-Jiang Wang et al.   NEUROTOXICITY RESEARCH

NFκB-dependent Control ofBACE1Promoter Transactivation by Aβ42

(2008) Virginie Buggia-Prevot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Amyloid1-42 Induces Neuronal Death through the p75 Neurotrophin Receptor

(2008) A. Sotthibundhu et al.   JOURNAL OF NEUROSCIENCE

Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration

(2008) Karun K Singh et al.   NATURE NEUROSCIENCE