ProBDNF and its receptors are upregulated in glioma and inhibit the growth of glioma cells in vitro

Role of Endogenous Brain-Derived Neurotrophic Factor and Sortilin in B Cell Survival

(2014) A.-L. Fauchais et al.   JOURNAL OF IMMUNOLOGY

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons

(2012) Sandra Dieni et al.   JOURNAL OF CELL BIOLOGY

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA

(2012) Ying Sun et al.   PLoS One

Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder

(2012) Taisuke Yoshida et al.   PLoS One

PDGF and PDGF receptors in glioma

(2012) Inga Nazarenko et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways

(2011) Anja C Pickhard et al.   BMC CANCER

Quantitative analysis of matrix metalloproteinase-2 mRNA expression in central and peripheral regions of gliomas

(2011) Marta Brell et al.   Brain Tumor Pathology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice

(2011) Zhi-Qiang Xu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing

(2011) Miao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional and post-transcriptional down-regulation of cyclin D1 contributes to C6 glioma cell differentiation induced by forskolin

(2011) Songmin He et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fine-Tuning Roles of Endogenous Brain-Derived Neurotrophic Factor, TrkB and Sortilin in Colorectal Cancer Cell Survival

(2011) Hussein Akil et al.   PLoS One

Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells

(2010) Hiromichi Nakabayashi et al.   BMC CANCER

Detection of failure of bevacizumab treatment for malignant glioma based on urinary matrix metalloproteinase activity

(2010) Shingo Takano et al.   Brain Tumor Pathology

Immunochemical Analysis of Glial Fibrillary Acidic Protein as a Tool to Assess Astroglial Reaction in Experimental C6 Glioma

(2010) G. M. Yusubalieva et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Antitumor progression potential of caffeic acid phenethyl ester involving p75NTR in C6 glioma cells

(2010) Wea-Lung Lin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons

(2010) Hisatsugu Koshimizu et al.   NEUROSCIENCE LETTERS

Proteomic analysis of low- to high-grade astrocytomas reveals an alteration of the expression level of raf kinase inhibitor protein and nucleophosmin

(2010) Marcela Gimenez et al.   PROTEOMICS

STAT3 Regulation of Glioblastoma Pathogenesis

(2009) Nuria la Iglesia et al.   CURRENT MOLECULAR MEDICINE

Imaging glioma cell invasionin vivoreveals mechanisms of dissemination and peritumoral angiogenesis

(2009) Frank Winkler et al.   GLIA

Cleavage of proBDNF to BDNF by a Tolloid-Like Metalloproteinase Is Required for Acquisition of In Vitro Eyeblink Classical Conditioning

(2009) J. Keifer et al.   JOURNAL OF NEUROSCIENCE

EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin

(2009) Haitao Ji et al.   MOLECULAR CELL

Whither proBDNF?

(2009) Philip A Barker   NATURE NEUROSCIENCE

Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas

(2008) C.-H. Kwon et al.   CANCER RESEARCH

Decreased Expression of Gastrokine 1 and the Trefoil Factor Interacting Protein TFIZ1/GKN2 in Gastric Cancer: Influence of Tumor Histology and Relationship to Prognosis

(2008) S. F. Moss et al.   CLINICAL CANCER RESEARCH

Differential effects of pro-BDNF on sensory neurons after sciatic nerve transection in neonatal rats

(2008) Yong-jun Fan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor

(2008) LiMei Wang et al.   PLOS BIOLOGY

Neurotrophin receptor expression in human primary retinoblastomas and retinoblastoma cell lines

(2007) Harald Stephan et al.   PEDIATRIC BLOOD & CANCER