Monitoring Autophagy Immunohistochemically and Ultrastructurally during Human Head and Neck Carcinogenesis. Relationship with the DNA Damage Response Pathway

Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy

(2017) Fei Xu et al.   Scientific Reports

Robust, universal biomarker assay to detect senescent cells in biological specimens

(2016) Konstantinos Evangelou et al.   AGING CELL

SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

(2016) Graeme Hewitt et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Autophagy substrate SQSTM1/p62 regulates chromatin ubiquitination during the DNA damage response

(2016) Yanan Wang et al.   Autophagy

p62 in Cancer: Signaling Adaptor Beyond Autophagy

(2016) Jorge Moscat et al.   CELL

p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer

(2016) Koji Taniguchi et al.   FEBS LETTERS

Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62

(2016) Yanan Wang et al.   MOLECULAR CELL

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

(2016) Panagiotis Galanos et al.   NATURE CELL BIOLOGY

The role of autophagy in squamous cell carcinoma of the head and neck

(2016) Benjamin Cosway et al.   ORAL ONCOLOGY

Autophagy: A boon or bane in oral cancer

(2016) Namrata Adhauliya et al.   ORAL ONCOLOGY

Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy

(2016) Kwan-Hwa Chi et al.   Oncotarget

Identifying an essential role of nuclear LC3 for autophagy

(2015) Rui Huang et al.   Autophagy

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation

(2015) Rui Huang et al.   MOLECULAR CELL

Autophagy at the crossroads of catabolism and anabolism

(2015) Jasvinder Kaur et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where

(2015) Ioannis S. Pateras et al.   PHARMACOLOGY & THERAPEUTICS

Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines

(2015) Michael I. Koukourakis et al.   PLoS One

Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer

(2015) Jing-Lan Liu et al.   PLoS One

Autophagy suppresses melanoma tumorigenesis by inducing senescence

(2014) He Liu et al.   Autophagy

Immunological significance of the accumulation of autophagy components in oral squamous cell carcinoma

(2014) Koichi Sakakura et al.   CANCER SCIENCE

Gene of the month:BECN1

(2014) Sumit Sahni et al.   JOURNAL OF CLINICAL PATHOLOGY

Systems biology of cisplatin resistance: past, present and future

(2014) L Galluzzi et al.   Cell Death & Disease

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

(2013) K Evangelou et al.   CELL DEATH AND DIFFERENTIATION

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prognostic Significance of Beclin-1 Expression in Laryngeal Squamous Cell Carcinoma

(2013) Li Huang et al.   PATHOLOGY & ONCOLOGY RESEARCH

Inhibition of autophagy-potentiated chemosensitivity to cisplatin in laryngeal cancer Hep-2 cells

(2012) Rong Kang et al.   AMERICAN JOURNAL OF OTOLARYNGOLOGY

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

Autophagic action of new targeting agents in head and neck oncology

(2012) Hidemi Rikiishi   CANCER BIOLOGY & THERAPY

p62: a versatile multitasker takes on cancer

(2012) Jorge Moscat et al.   TRENDS IN BIOCHEMICAL SCIENCES

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer

(2011) Gui-Fang Guo   WORLD JOURNAL OF GASTROENTEROLOGY

Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma

(2010) Xiang-Bo Wan et al.   Autophagy

Oncogene-induced senescence: the bright and dark side of the response

(2010) Vassilis G Gorgoulis et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Nucleocytoplasmic Distribution and Dynamics of the Autophagosome Marker EGFP-LC3

(2010) Kimberly R. Drake et al.   PLoS One

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Autophagy and Tumorigenesis

(2010) Srirupa Roy et al.   Seminars in Immunopathology

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies

(2009) Serhiy Pankiv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L

(2008) I Papandreou et al.   CELL DEATH AND DIFFERENTIATION

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Regulation of macroautophagy by mTOR and Beclin 1 complexes

(2007) Sophie Pattingre et al.   BIOCHIMIE