The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 18, Issue 3, Pages 657
Publisher
MDPI AG
Online
2017-03-17
DOI
10.3390/ijms18030657
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
- (2016) Naila Rabbani et al. GLYCOCONJUGATE JOURNAL
- Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study
- (2016) INTENSIVE CARE MEDICINE
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells
- (2016) Jakob Morgenstern et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-Docosahexaenoylethanolamine ameliorates LPS-induced neuroinflammation via cAMP/PKA-dependent signaling
- (2016) Taeyeop Park et al. Journal of Neuroinflammation
- RAGE-mediated inflammation in patients with septic shock
- (2016) Stefan Hofer et al. JOURNAL OF SURGICAL RESEARCH
- The reciprocal interaction of sympathetic nervous system and cAMP-PKA-NF-kB pathway in immune suppression after experimental stroke
- (2016) Lei Zuo et al. NEUROSCIENCE LETTERS
- Mitochondrial Function in Sepsis
- (2016) Nishkantha Arulkumaran et al. SHOCK
- The Endothelium in Sepsis
- (2016) Can Ince et al. SHOCK
- Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease
- (2015) Naila Rabbani et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival
- (2015) Ulf H. Beier et al. FASEB JOURNAL
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Role of the RAGE Axis during the Immune Response after Severe Trauma: A Prospective Pilot Study
- (2015) Florian Uhle et al. MEDIATORS OF INFLAMMATION
- Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
- (2015) Sharad Shrestha et al. NATURE IMMUNOLOGY
- Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
- (2015) Alexandria Huynh et al. NATURE IMMUNOLOGY
- Cytopathic Hypoxia and Sepsis
- (2015) Mitchell P. Fink Pediatric Critical Care Medicine
- mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation
- (2015) Jong-Seok Moon et al. Cell Reports
- Defence against methylglyoxal in Group AStreptococcus: a role for Glyoxylase I in bacterial virulence and survival in neutrophils?
- (2015) May M. Zhang et al. Pathogens and Disease
- Glyoxalase Centennial conference: introduction, history of research on the glyoxalase system and future prospects
- (2014) Naila Rabbani et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Metabolic response to the stress of critical illness
- (2014) J.-C. Preiser et al. BRITISH JOURNAL OF ANAESTHESIA
- Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy
- (2014) D J Roberts et al. CELL DEATH AND DIFFERENTIATION
- Cardiac mitochondrial biogenesis in endotoxemia is not accompanied by mitochondrial function recovery
- (2014) Virginia Vanasco et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012
- (2014) Kirsi-Maija Kaukonen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
- (2014) Valerie A. Gerriets et al. JOURNAL OF CLINICAL INVESTIGATION
- mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
- (2014) Raymond P. Donnelly et al. JOURNAL OF IMMUNOLOGY
- Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples
- (2014) Naila Rabbani et al. Nature Protocols
- Cytokine and Nitric Oxide Levels in Patients with Sepsis – Temporal Evolvement and Relation to Platelet Mitochondrial Respiratory Function
- (2014) Fredrik Sjövall et al. PLoS One
- The Warburg effect then and now: From cancer to inflammatory diseases
- (2013) Eva M. Palsson-McDermott et al. BIOESSAYS
- Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis
- (2013) D.A. Lowes et al. BRITISH JOURNAL OF ANAESTHESIA
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
- (2013) Kairui Mao et al. CELL RESEARCH
- Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012
- (2013) R. P. Dellinger et al. INTENSIVE CARE MEDICINE
- Reactive Metabolites and AGE-RAGE-Mediated Inflammation in Patients following Liver Transplantation
- (2013) Thorsten Brenner et al. MEDIATORS OF INFLAMMATION
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
- (2012) Angelika Bierhaus et al. NATURE MEDICINE
- Generation of Nitric Oxide and Reactive Oxygen Species by Neutrophils and Monocytes From Septic Patients and Association With Outcomes
- (2012) Sidnéia Sousa Santos et al. SHOCK
- Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
- (2011) Weibo Luo et al. CELL
- Cyclic AMP: a selective modulator of NF-κB action
- (2011) Sarah Gerlo et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology
- (2011) A. K. Berner et al. DIABETOLOGIA
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- A Global Perspective of the Genetic Basis for Carbonyl Stress Resistance
- (2011) Shawn Hoon et al. G3-Genes Genomes Genetics
- Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
- (2010) C. M. Krawczyk et al. BLOOD
- Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose
- (2010) Arti Dhar et al. BRITISH JOURNAL OF PHARMACOLOGY
- Reactive Metabolites and AGE/RAGE-Mediated Cellular Dysfunction Affect the Aging Process – A Mini-Review
- (2010) Thomas H. Fleming et al. GERONTOLOGY
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Hyperglycemia-Induced Reactive Oxygen Species Increase Expression of the Receptor for Advanced Glycation End Products (RAGE) and RAGE Ligands
- (2009) D. Yao et al. DIABETES
- Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes
- (2009) Beatriz Duran-Jimenez et al. DIABETES
- C. elegans as Model for the Study of High Glucose- Mediated Life Span Reduction
- (2009) A. Schlotterer et al. DIABETES
- Stress hyperglycaemia
- (2009) Kathleen M Dungan et al. LANCET
- Intensive versus Conventional Glucose Control in Critically Ill Patients
- (2009) NEW ENGLAND JOURNAL OF MEDICINE
- The GAIT system: a gatekeeper of inflammatory gene expression
- (2009) Rupak Mukhopadhyay et al. TRENDS IN BIOCHEMICAL SCIENCES
- Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans
- (2008) Michael Morcos et al. AGING CELL
- Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress
- (2008) Naila Rabbani et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Cellular energetic metabolism in sepsis: The need for a systems approach
- (2008) Jane E. Carré et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- Role of Glyceraldehyde 3-Phosphate Dehydrogenase in the Development and Progression of Diabetic Retinopathy
- (2008) M. Kanwar et al. DIABETES
- Benefits and Risks of Tight Glucose Control in Critically Ill Adults
- (2008) Renda Soylemez Wiener et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Inflammatory Response in Microvascular Endothelium in Sepsis: Role of Oxidants
- (2008) Gediminas Cepinskas et al. JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION
- The tandem of free radicals and methylglyoxal
- (2007) Miklós Péter Kalapos CHEMICO-BIOLOGICAL INTERACTIONS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started