Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation

Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity

(2017) Chih-Yang Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway

(2017) Hsien-Chuen Soo et al.   PLoS One

Treatment patterns of advanced malignant melanoma (stage III–IV) – A review of current standards in Europe

(2016) Mark Harries et al.   EUROPEAN JOURNAL OF CANCER

Exploring the molecular targets of dietary flavonoid fisetin in cancer

(2016) Deeba N. Syed et al.   SEMINARS IN CANCER BIOLOGY

Flavonoid C-glucosides Derived from Flax Straw Extracts Reduce Human Breast Cancer Cell Growth In vitro and Induce Apoptosis

(2016) Magdalena Czemplik et al.   Frontiers in Pharmacology

Stage-specific survival and recurrence in patients with cutaneous malignant melanoma in Europe – a systematic review of the literature

(2016) Fernanda Costa Svedman et al.   Clinical Epidemiology

Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis

(2016) Shikha Srivastava et al.   Scientific Reports

Artocarpin Induces Apoptosis in Human Cutaneous Squamous Cell Carcinoma HSC-1 Cells and Its Cytotoxic Activity Is Dependent on Protein-Nutrient Concentration

(2015) Stephen Chu-Sung Hu et al.   Evidence-based Complementary and Alternative Medicine

Chemical constituents derived from Artocarpus xanthocarpus as inhibitors of melanin biosynthesis

(2015) Yu-Jing Jin et al.   PHYTOCHEMISTRY

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models

(2014) D J Colin et al.   Cell Death & Disease

ROS-Mediated Lipid Peroxidation and RES-Activated Signaling

(2013) Edward E. Farmer et al.   Annual Review of Plant Biology

Antityrosinase and antimicrobial activities from Thai medicinal plants

(2013) Sukanya Dej-adisai et al.   ARCHIVES OF PHARMACAL RESEARCH

Protein Oxidation: Basic Principles and Implications for Meat Quality

(2013) Wangang Zhang et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Antioxidant therapeutics: Pandora′s box

(2013) Brian J. Day   FREE RADICAL BIOLOGY AND MEDICINE

Cutaneous melanoma

(2013) Alexander MM Eggermont et al.   LANCET

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management

(2012) Vaqar Mustafa Adhami et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells

(2012) Xiuzhen Han et al.   CARCINOGENESIS

New Isoprenylated Flavones and Stilbene Derivative from Artocarpus hypargyreus

(2012) Mei-Hua Yu et al.   CHEMISTRY & BIODIVERSITY

Aldehyde dehydrogenases in cellular responses to oxidative/electrophilicstress

(2012) Surendra Singh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation

(2011) Huibin Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A novel non-aromatic B-ring flavonoid: Isolation, structure elucidation and its induction of apoptosis in human colon HT-29 tumor cell via the reactive oxygen species-mitochondrial dysfunction and MAPK activation

(2011) Anhua Wei et al.   FOOD AND CHEMICAL TOXICOLOGY

Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA

(2011) Zsolt Radak et al.   MOLECULAR ASPECTS OF MEDICINE

Tricetin, a Dietary Flavonoid, Induces Apoptosis through the Reactive Oxygen Species/c-Jun NH2-Terminal Kinase Pathway in Human Liver Cancer Cells

(2010) Ya-Ling Hsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

New isoprenylated flavonoids and cytotoxic constituents fromArtocarpus tonkinensis

(2010) Jian-Ping Ma et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

New Isoprenylated 2-Arylbenzofurans and Pancreatic Lipase Inhibitory Constituents from Artocarpus nitidus

(2009) Ting Zhao et al.   CHEMISTRY & BIODIVERSITY

Isoprenoid-substituted flavonoids from wood of Artocarpus heterophyllus on B16 melanoma cells: Cytotoxicity and structural criteria

(2009) Enos Tangke Arung et al.   FITOTERAPIA

Luteolin, a Flavonoid with Potential for Cancer Prevention and Therapy

(2008) Yong Lin et al.   CURRENT CANCER DRUG TARGETS

Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer

(2008) T. Boutros et al.   PHARMACOLOGICAL REVIEWS