Valproate Attenuates Endoplasmic Reticulum Stress-Induced Apoptosis in SH-SY5Y Cells via the AKT/GSK3β Signaling Pathway

Beta-adrenoceptor Activation by Norepinephrine Enhances Lipopolysaccharide-induced Matrix Metalloproteinase-9 Expression Through the ERK/JNK-c-Fos Pathway in Human THP-1 Cells

(2017) Xiang Yin et al.   Journal of Atherosclerosis and Thrombosis

Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma

(2016) Zenpei Shigemi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Isoquercetin ameliorates tunicamycin-induced apoptosis in rat dorsal root ganglion neurons via suppressing ROS-dependent endoplasmic reticulum stress

(2016) Tan Lu et al.   BIOMEDICINE & PHARMACOTHERAPY

Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway

(2016) Congcong Wang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals

(2016) María Martínez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isoquercitrin Inhibits Hydrogen Peroxide-Induced Apoptosis of EA.hy926 Cells via the PI3K/Akt/GSK3β Signaling Pathway

(2016) Meixia Zhu et al.   MOLECULES

Neuroprotective Effects of Valproic Acid on Blood-Brain Barrier Disruption and Apoptosis-Related Early Brain Injury in Rats Subjected to Subarachnoid Hemorrhage Are Modulated by Heat Shock Protein 70/Matrix Metalloproteinases and Heat Shock Protein 70/AKT Pathways

(2016) Guang-yu Ying et al.   NEUROSURGERY

AKT activation controls cell survival in response to HDAC6 inhibition

(2016) M Kaliszczak et al.   Cell Death & Disease

Propofol Decreases Endoplasmic Reticulum Stress–Mediated Apoptosis in Retinal Pigment Epithelial Cells

(2016) Xuezhi Zhou et al.   PLoS One

The Neuroprotection of Liraglutide Against Ischaemia-induced Apoptosis through the Activation of the PI3K/AKT and MAPK Pathways

(2016) Huili Zhu et al.   Scientific Reports

Targeting the unfolded protein response for disease intervention

(2015) Alexis Rivas et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Protective effect of valproic acid on cultured motor neurons under glutamate excitotoxic conditions. Ultrastructural study

(2015) Ewa Nagańska et al.   FOLIA NEUROPATHOLOGICA

Role for the Unfolded Protein Response in Heart Disease and Cardiac Arrhythmias

(2015) Man Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma

(2015) Ju-Fang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes

(2015) Sumaira Z Hasnain et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Endoplasmic reticulum stress is involved in apoptosis of detrusor muscle in streptozocin-induced diabetic rats

(2015) Dongwen Wang et al.   NEUROUROLOGY AND URODYNAMICS

Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease

(2015) Mojtaba Golpich et al.   PHARMACOLOGICAL RESEARCH

Valproic acid-mediated neuroprotection and neurogenesis after spinal cord injury: from mechanism to clinical potential

(2015) Tianci Chu et al.   Regenerative Medicine

Downregulation of matrix metalloproteinases contributes to the inhibition of cell migration and invasion in HepG2 cells by sodium valproate

(2015) XIA ZHAO et al.   Oncology Letters

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells

(2015) Dinesh Thotala et al.   Oncotarget

Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM

(2015) Maja T. Tomicic et al.   Oncotarget

Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

(2015) Sofia Esteves et al.   PLoS One

Neuroprotective and anti-apoptotic effects of valproic acid on adult rat cerebral cortex through ERK and Akt signaling pathway at acute phase of traumatic brain injury

(2014) Chi Zhang et al.   BRAIN RESEARCH

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

(2014) Bianca Pfaffenseller et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury

(2014) Hongyu Zhang et al.   Journal of Translational Medicine

Endoplasmic Reticulum Stress: Relevance and Therapeutics in Central Nervous System Diseases

(2014) Hong-Yu Zhang et al.   MOLECULAR NEUROBIOLOGY

Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia

(2014) V. Singh et al.   NEUROSCIENCE

Neuroprotection by valproic acid in an intrastriatal rotenone model of Parkinson’s disease

(2014) C.H. Carriere et al.   NEUROSCIENCE

Down-regulation of GRP78 enhances apoptosis via CHOP pathway in retinal ischemia-reperfusion injury

(2014) Huiling Li et al.   NEUROSCIENCE LETTERS

Calcium and mitochondrial metabolism in ceramide-induced cardiomyocyte death

(2013) Valentina Parra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Valproic Acid Regulates α-Synuclein Expression through JNK Pathway in Rat Primary Astrocytes

(2013) Jung Nam Kim et al.   Biomolecules & Therapeutics

Valproic Acid Protects Motor Neuron Death by Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress-Mediated Cytochrome C Release after Spinal Cord Injury

(2013) Jee Y. Lee et al.   JOURNAL OF NEUROTRAUMA

Valproic acid enhances early development of bovine somatic cell nuclear transfer embryos by alleviating endoplasmic reticulum stress

(2013) Bong-Seok Song et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

(2012) Suneng Fu et al.   Cell Metabolism

Endoplasmic reticulum stress and its regulator XBP-1 contributes to dendritic cell maturation and activation induced by high mobility group box-1 protein

(2012) Xiao-mei Zhu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation

(2011) ZhenZhen Zhang et al.   EXPERIMENTAL EYE RESEARCH

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

(2011) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

Valproate reduces CHOP levels and preserves oligodendrocytes and axons after spinal cord injury

(2011) C. Penas et al.   NEUROSCIENCE

Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice

(2010) Jin Hwan Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Peptide-binding heat shock protein GRP78 protects cardiomyocytes from hypoxia-induced apoptosis

(2010) Britta Hardy et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease

(2010) Arianna Bellucci et al.   JOURNAL OF NEUROCHEMISTRY

Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia

(2010) Nobuhiro Osada et al.   NEUROCHEMISTRY INTERNATIONAL

Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder

(2008) Akiko Hayashi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY