Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease
Authors
Keywords
Mouse models, Body weight, Cerebellum, Genetically modified animals, Swimming, Animal performance, Histone acetylation, Biological locomotion
Journal
PLoS One
Volume 10, Issue 10, Pages e0141610
Publisher
Public Library of Science (PLoS)
Online
2015-10-28
DOI
10.1371/journal.pone.0141610
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Valproic acid attenuates the suppression of acetyl histone H3 and CREB activity in an inducible cell model of Machado–Joseph disease
- (2014) X.P. Lin et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- FELASA recommendations for the health monitoring of mouse, rat, hamster, guinea pig and rabbit colonies in breeding and experimental units
- (2014) et al. LABORATORY ANIMALS
- Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease
- (2014) Anabela Silva-Fernandes et al. Neurotherapeutics
- From Pathways to Targets: Understanding the Mechanisms behind Polyglutamine Disease
- (2014) Jonasz Jeremiasz Weber et al. Biomed Research International
- Genomic Landscape of Transcriptional and Epigenetic Dysregulation in Early Onset Polyglutamine Disease
- (2013) L. M. Valor et al. JOURNAL OF NEUROSCIENCE
- Sodium Valproate Alleviates Neurodegeneration in SCA3/MJD via Suppressing Apoptosis and Rescuing the Hypoacetylation Levels of Histone H3 and H4
- (2013) Jiping Yi et al. PLoS One
- Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans : rescue by the DAF-16 and HSF-1 pathways
- (2011) Andreia Teixeira-Castro et al. HUMAN MOLECULAR GENETICS
- Hormonal and reproductive disturbances in epileptic male patients: Emerging issues
- (2011) Alberto Verrotti et al. REPRODUCTIVE TOXICOLOGY
- Axonal inclusions in spinocerebellar ataxia type 3
- (2010) Kay Seidel et al. ACTA NEUROPATHOLOGICA
- Mechanisms of Synergistic Antileukemic Interactions between Valproic Acid and Cytarabine in Pediatric Acute Myeloid Leukemia
- (2010) C. Xie et al. CLINICAL CANCER RESEARCH
- Motor uncoordination and neuropathology in a transgenic mouse model of Machado–Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products
- (2010) Anabela Silva-Fernandes et al. NEUROBIOLOGY OF DISEASE
- HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3
- (2010) An-Hsun Chou et al. NEUROBIOLOGY OF DISEASE
- Weight gain following treatment with valproic acid: pathogenetic mechanisms and clinical implications
- (2010) A. Verrotti et al. Obesity Reviews
- New insights into the pathoanatomy of spinocerebellar ataxia type 3 (Machado–Joseph disease)
- (2009) Udo Rüb et al. CURRENT OPINION IN NEUROLOGY
- The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies
- (2009) Peter O. Bauer et al. JOURNAL OF NEUROCHEMISTRY
- Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
- (2009) Dénes Zádori et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Valproic acid in pregnancy: How much are we endangering the embryo and fetus?
- (2009) Asher Ornoy REPRODUCTIVE TOXICOLOGY
- Body Mass Index and Serum Lipid Changes During Treatment with Valproic Acid in Children with Epilepsy
- (2008) Salvatore Grosso et al. ANNALS OF PHARMACOTHERAPY
- Increase in antiepileptic efficacy during prolonged treatment with valproic acid: Role of inhibition of histone deacetylases?
- (2008) Katrin Hoffmann et al. EPILEPSY RESEARCH
- Histone deacetylase inhibitors: possible implications for neurodegenerative disorders
- (2008) Eric Hahnen et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Valproic acid enhances bosutinib cytotoxicity in colon cancer cells
- (2008) Luca Mologni et al. INTERNATIONAL JOURNAL OF CANCER
- Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice
- (2008) Li-Kai Tsai et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Evaluation of the Mood-Stabilizing Agent Valproic Acid as a Preventative for Toxoplasmosis In Mice and Activity Against Tissue Cysts in Mice
- (2008) David G. Goodwin et al. JOURNAL OF PARASITOLOGY
- Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial
- (2008) CK Martin et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
- (2008) Aleksey G. Kazantsev et al. NATURE REVIEWS DRUG DISCOVERY
- Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
- (2008) H.-L. Feng et al. NEUROSCIENCE
- Disorders of reproduction in patients with epilepsy: Antiepileptic drug related mechanisms
- (2008) Jouko Isojärvi SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started