LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1

(2013) M. G. A. van Eupen et al.   DIABETOLOGIA

Methylglyoxal promotes oxidative stress and endothelial dysfunction

(2012) Cristina M. Sena et al.   PHARMACOLOGICAL RESEARCH

Methylglyoxal-mediated alteration of gene expression in human endothelial cells

(2011) Seung Eun Lee et al.   BioChip Journal

Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose

(2010) Arti Dhar et al.   BRITISH JOURNAL OF PHARMACOLOGY

The RAGE Axis

(2010) Shi Fang Yan et al.   CIRCULATION RESEARCH

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells

(2009) Noriko Miyazawa et al.   FREE RADICAL RESEARCH

Control of mitochondrial apoptosis by the Bcl-2 family

(2009) J. K. Brunelle et al.   JOURNAL OF CELL SCIENCE

Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells

(2008) Hideyuki Yamawaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Telmisartan inhibits methylglyoxal-mediated cell death in human vascular endothelium

(2008) Tatsuya Baden et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A new advanced glycation inhibitor, LR-90, prevents experimental diabetic retinopathy in rats

(2008) A Bhatwadekar et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells

(2008) Shang-Ming Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inhibitory effect of vanillic acid on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells

(2008) Shang-Ming Huang et al.   NEUROTOXICOLOGY

Methylglyoxal-induced Apoptosis of Endothelial Cells

(2008) Kyohei TAKAHASHI et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN