Involvement of Astrocytes in Mediating the Central Effects of Ghrelin

The neurological effects of ghrelin in brain diseases: Beyond metabolic functions

(2017) Qian Jiao et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice

(2016) J. M. Ku et al.   CLINICAL SCIENCE

The insulin-like growth factor I receptor regulates glucose transport by astrocytes

(2016) Edwin Hernandez-Garzón et al.   GLIA

A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons

(2016) Gemma Navarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glial cells and energy balance

(2016) Pilar Argente-Arizón et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease

(2016) J. A. Bayliss et al.   JOURNAL OF NEUROSCIENCE

Ghrelin and Neurodegenerative Disorders—a Review

(2016) Limin Shi et al.   MOLECULAR NEUROBIOLOGY

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Functional diversity of astrocytes in neural circuit regulation

(2016) Lucile Ben Haim et al.   NATURE REVIEWS NEUROSCIENCE

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals

(2016) Julie A. Chowen et al.   PROGRESS IN NEUROBIOLOGY

Ghrelin O-acyltransferase (GOAT) and energy metabolism

(2016) Ziru Li et al.   Science China-Life Sciences

Obesity Impairs the Action of the Neuroendocrine Ghrelin System

(2016) Jeffrey M. Zigman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ghrelin Regulates Glucose and Glutamate Transporters in Hypothalamic Astrocytes

(2016) Esther Fuente-Martín et al.   Scientific Reports

The Neuroprotective Effect of the Association of Aquaporin-4/Glutamate Transporter-1 against Alzheimer’s Disease

(2016) Yu-Long Lan et al.   NEURAL PLASTICITY

SnapShot: Astrocytes in Health and Disease

(2015) Shane Liddelow et al.   CELL

Palatability Can Drive Feeding Independent of AgRP Neurons

(2015) Raphaël G.P. Denis et al.   Cell Metabolism

Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF

(2015) Roman Fischer et al.   Oxidative Medicine and Cellular Longevity

Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell–cell communication by chemokines

(2015) Stefka Gyoneva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

High Fat Diet and Inflammation – Modulation of Haptoglobin Level in Rat Brain

(2015) Maria Stefania Spagnuolo et al.   Frontiers in Cellular Neuroscience

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Neuroinflammation and Aβ Accumulation Linked To Systemic Inflammation Are Decreased By Genetic PKR Down-Regulation

(2015) Anne-Sophie Carret-Rebillat et al.   Scientific Reports

The transmembrane transporter domain of glutamate transporters is a process tip localizer

(2015) Mariko Kato Hayashi et al.   Scientific Reports

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors

(2015) Liang Yang et al.   Cell Reports

Neonatal overnutrition causes early alterations in the central response to peripheral ghrelin

(2015) Gustav Collden et al.   Molecular Metabolism

Ghrelin

(2015) T.D. Müller et al.   Molecular Metabolism

Ghrelin accelerates synapse formation and activity development in cultured cortical networks

(2014) Irina I Stoyanova et al.   BMC NEUROSCIENCE

Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain

(2014) Eglantine Balland et al.   Cell Metabolism

The Opposing Effects of Ghrelin on Hypothalamic and Systemic Inflammatory Processes Are Modulated by Its Acylation Status and Food Intake in Male Rats

(2014) Cristina García-Cáceres et al.   ENDOCRINOLOGY

Evidence That Diet-Induced Hyperleptinemia, but Not Hypothalamic Gliosis, Causes Ghrelin Resistance in NPY/AgRP Neurons of Male Mice

(2014) Dana I. Briggs et al.   ENDOCRINOLOGY

MicroRNA-145 as one negative regulator of astrogliosis

(2014) Chih-Yen Wang et al.   GLIA

Nutritional State-Dependent Ghrelin Activation of Vasopressin Neurons via Retrograde Trans-Neuronal-Glial Stimulation of Excitatory GABA Circuits

(2014) J. Haam et al.   JOURNAL OF NEUROSCIENCE

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

(2014) Ricardo Cabezas et al.   Frontiers in Cellular Neuroscience

Peptides and Food Intake

(2014) Carmen Sobrino Crespo et al.   Frontiers in Endocrinology

Endogenous ghrelin's role in hippocampal neuroprotection after global cerebral ischemia: does endogenous ghrelin protect against global stroke?

(2013) Rachel Kenny et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

(2013) Jean-Luc Martin et al.   CURRENT DRUG TARGETS

Both Acyl and Des-Acyl Ghrelin Regulate Adiposity and Glucose Metabolism via Central Nervous System Ghrelin Receptors

(2013) K. M. Heppner et al.   DIABETES

Differential effects of GH and GH-releasing peptide-6 on astrocytes

(2013) Eva Baquedano et al.   JOURNAL OF ENDOCRINOLOGY

Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells

(2013) Hyunju Chung et al.   JOURNAL OF ENDOCRINOLOGY

Effect of ghrelin on brain edema induced by acute and chronic systemic hypoxia

(2013) Fezzeh Hossienzadeh et al.   NEUROSCIENCE LETTERS

Cardioprotective Effect of Ghrelin in Cardiopulmonary Bypass Involves a Reduction in Inflammatory Response

(2013) Yukun Cao et al.   PLoS One

Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

(2013) Marie Schaeffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen, astrocytes and the neuroendocrine control of metabolism

(2013) E. Fuente-Martin et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Early postnatal overnutrition increases adipose tissue accrual in response to a sucrose-enriched diet

(2012) Esther Fuente-Martín et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ghrelin Signaling in the Ventral Hippocampus Stimulates Learned and Motivational Aspects of Feeding via PI3K-Akt Signaling

(2012) Scott E. Kanoski et al.   BIOLOGICAL PSYCHIATRY

Early ghrelin treatment attenuates disruption of the blood brain barrier and apoptosis after traumatic brain injury through a UCP-2 mechanism

(2012) N.E. Lopez et al.   BRAIN RESEARCH

Astrocytes and disease: a neurodevelopmental perspective

(2012) A. V. Molofsky et al.   GENES & DEVELOPMENT

Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes

(2012) Esther Fuente-Martín et al.   JOURNAL OF CLINICAL INVESTIGATION

Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation

(2012) Sungyoub Lee et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Ghrelin signalling and obesity: At the interface of stress, mood and food reward

(2012) Harriët Schellekens et al.   PHARMACOLOGY & THERAPEUTICS

The GOAT-Ghrelin System Is Not Essential for Hypoglycemia Prevention during Prolonged Calorie Restriction

(2012) Chun-Xia Yi et al.   PLoS One

Role of Gap Junction Protein Connexin43 in Astrogliosis Induced by Brain Injury

(2012) Nicolas Theodoric et al.   PLoS One

Emerging role of glial cells in the control of body weight

(2012) Cristina García-Cáceres et al.   Molecular Metabolism

Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression

(2011) Karolina P. Skibicka et al.   ADDICTION BIOLOGY

Immunomodulatory actions of central ghrelin in diet-induced energy imbalance

(2011) Darko Stevanovic et al.   BRAIN BEHAVIOR AND IMMUNITY

Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop

(2011) Yunlei Yang et al.   CELL

Metabolic Sensing and the Brain: Who, What, Where, and How?

(2011) Barry E. Levin et al.   ENDOCRINOLOGY

Differential Acute and Chronic Effects of Leptin on Hypothalamic Astrocyte Morphology and Synaptic Protein Levels

(2011) Cristina García-Cáceres et al.   ENDOCRINOLOGY

Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β pathways

(2011) Eunjin Lim et al.   EXPERIMENTAL NEUROLOGY

Dynamic monitoring of cytosolic glucose in single astrocytes

(2011) Mateja Prebil et al.   GLIA

Ghrelin induces cell migration through GHS-R, CaMKII, AMPK, and NF-κB signaling pathway in glioma cells

(2011) Jia-Hong Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ghrelin Prevents Disruption of the Blood–Brain Barrier after Traumatic Brain Injury

(2011) Nicole E. Lopez et al.   JOURNAL OF NEUROTRAUMA

Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats

(2011) Esther Fuente-Martín et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The role of the central ghrelin system in reward from food and chemical drugs

(2011) Suzanne L. Dickson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The effects of ghrelin on inflammation and the immune system

(2011) Dolgor Baatar et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The truncated ghrelin receptor polypeptide (GHS-R1b) is localized in the endoplasmic reticulum where it forms heterodimers with ghrelin receptors (GHS-R1a) to attenuate their cell surface expression

(2011) Kevin B.S. Chow et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

The stem cell potential of glia: lessons from reactive gliosis

(2011) Stefanie Robel et al.   NATURE REVIEWS NEUROSCIENCE

Reward Mechanisms in Obesity: New Insights and Future Directions

(2011) Paul J. Kenny   NEURON

Inflammation and prevention of epileptogenesis

(2011) Teresa Ravizza et al.   NEUROSCIENCE LETTERS

Integrated Brain Circuits: Astrocytic Networks Modulate Neuronal Activity and Behavior

(2010) Michael M. Halassa et al.   Annual Review of Physiology

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

(2010) J J Kim et al.   CELL DEATH AND DIFFERENTIATION

The role of gut hormones and the hypothalamus in appetite regulation

(2010) Keisuke Suzuki et al.   ENDOCRINE JOURNAL

Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity

(2010) Linda A.W. Verhagen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Ghrelin attenuates kainic acid-induced neuronal cell death in the mouse hippocampus

(2010) Jiyeon Lee et al.   JOURNAL OF ENDOCRINOLOGY

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specification and Morphogenesis of Astrocytes

(2010) M. R. Freeman   SCIENCE

Ghrelin Suppresses Inflammation and Neuronal Nitric Oxide Synthase in Focal Cerebral Ischemia Via the Vagus Nerve

(2010) Cletus Cheyuo et al.   SHOCK

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Astrocytic dysfunction: Insights on the role in neurodegeneration

(2009) Daniela Rossi et al.   BRAIN RESEARCH BULLETIN

Ghrelin in Central Neurons

(2009) F. Ferrini et al.   Current Neuropharmacology

Growth hormone-releasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulin-like growth factor I

(2009) A. Delgado-Rubín et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Synaptic potentiation induces increased glial coverage of excitatory synapses in CA1 hippocampus

(2009) Irina Lushnikova et al.   HIPPOCAMPUS

Thein vivoneuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

(2009) Silvia Mangia et al.   JOURNAL OF NEUROCHEMISTRY

Ghrelin Promotes and Protects Nigrostriatal Dopamine Function via a UCP2-Dependent Mitochondrial Mechanism

(2009) Z. B. Andrews et al.   JOURNAL OF NEUROSCIENCE

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Astrocytes going live: advances and challenges

(2009) Axel Nimmerjahn   JOURNAL OF PHYSIOLOGY-LONDON

Hormone and glucose signalling in POMC and AgRP neurons

(2009) Bengt F. Belgardt et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cerebral activation by fasting induces lactate accumulation in the hypothalamus

(2009) Inês R. Violante et al.   MAGNETIC RESONANCE IN MEDICINE

Tripartite synapses: Roles for astrocytic purines in the control of synaptic physiology and behavior

(2009) Michael M. Halassa et al.   NEUROPHARMACOLOGY

Ghrelin protects against cell death of hippocampal neurons in pilocarpine-induced seizures in rats

(2009) Jingjing Xu et al.   NEUROSCIENCE LETTERS

Neuroprotective Effect of Ghrelin in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson’s Disease by Blocking Microglial Activation

(2009) Minho Moon et al.   NEUROTOXICITY RESEARCH

Requirement of central ghrelin signaling for alcohol reward

(2009) E. Jerlhag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Brain Regulation of Appetite and Satiety

(2008) Rexford S. Ahima et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

A life course of adiposity and dementia

(2008) Deborah Gustafson   EUROPEAN JOURNAL OF PHARMACOLOGY

Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra

(2008) Hong Jiang et al.   EXPERIMENTAL NEUROLOGY

Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen–glucose deprivation-induced apoptosis in primary rat cortical neuronal cells

(2008) Hyunju Chung et al.   JOURNAL OF ENDOCRINOLOGY

Ghrelin Antagonized 1-Methyl-4-Phenylpyridinium (MPP+)-Induced Apoptosis in MES23.5 Cells

(2008) Juanjuan Dong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A single night of sleep deprivation increases ghrelin levels and feelings of hunger in normal-weight healthy men

(2008) SEBASTIAN M. SCHMID et al.   JOURNAL OF SLEEP RESEARCH

Coupling of Neural Activity to Blood Flow in Olfactory Glomeruli Is Mediated by Astrocytic Pathways

(2008) Gabor C. Petzold et al.   NEURON

Activity-Dependent Structural and Functional Plasticity of Astrocyte-Neuron Interactions

(2008) Dionysia T. Theodosis et al.   PHYSIOLOGICAL REVIEWS

Ghrelin octanoylation mediated by an orphan lipid transferase

(2008) J. A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kainate Glutamate Receptors (GluR5-7) in the Rat Arcuate Nucleus: Relationship to Tanycytes, Astrocytes, Neurons and Gonadal Steroid Receptors

(2003) Sabrina Diano et al.   JOURNAL OF NEUROENDOCRINOLOGY