Glial cells and energy balance

Signaling mechanisms underlying the glioprotective effects of resveratrol against mitochondrial dysfunction

(2016) Bruna Bellaver et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Maternal Obesity in the Mouse Compromises the Blood-Brain Barrier in the Arcuate Nucleus of Offspring

(2016) Dong Won Kim et al.   ENDOCRINOLOGY

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

Physical exercise increases adult hippocampal neurogenesis in male rats provided it is aerobic and sustained

(2016) Miriam S. Nokia et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glucose and hypothalamic astrocytes: More than a fueling role?

(2016) C. Leloup et al.   NEUROSCIENCE

Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions

(2016) Estefanía Acaz-Fonseca et al.   PROGRESS IN NEUROBIOLOGY

Ghrelin Regulates Glucose and Glutamate Transporters in Hypothalamic Astrocytes

(2016) Esther Fuente-Martín et al.   Scientific Reports

A sexually dimorphic hypothalamic response to chronic high-fat diet consumption

(2015) E Morselli et al.   INTERNATIONAL JOURNAL OF OBESITY

Dual signal transduction pathways activated by TSH receptors in rat primary tanycyte cultures

(2015) M. Bolborea et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The sexual dimorphism of obesity

(2015) Biff F. Palmer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors

(2015) Liang Yang et al.   Cell Reports

Hypothalamic tanycytes—masters and servants of metabolic, neuroendocrine, and neurogenic functions

(2015) Timothy Goodman et al.   Frontiers in Neuroscience

Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice

(2015) Laura B. Buckman et al.   Molecular Metabolism

Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term

(2014) Ilvana Ziko et al.   BRAIN BEHAVIOR AND IMMUNITY

Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain

(2014) Eglantine Balland et al.   Cell Metabolism

Hypothalamic Subependymal Niche: A Novel Site of the Adult Neurogenesis

(2014) Ewa Rojczyk-Gołębiewska et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity

(2014) M. F. White   DIABETES OBESITY & METABOLISM

Hypothalamic Gliosis Associated With High-Fat Diet Feeding Is Reversible in Mice: A Combined Immunohistochemical and Magnetic Resonance Imaging Study

(2014) Kathryn E. Berkseth et al.   ENDOCRINOLOGY

Aromatase Inhibition Exacerbates Pain and Reactive Gliosis in the Dorsal Horn of the Spinal Cord of Female Rats Caused by Spinothalamic Tract Injury

(2014) Samar Ghorbanpoor et al.   ENDOCRINOLOGY

Oestradiol and Diet Modulate Energy Homeostasis and Hypothalamic Neurogenesis in the Adult Female Mouse

(2014) E. P. Bless et al.   JOURNAL OF NEUROENDOCRINOLOGY

Betaine recovers hypothalamic neural injury by inhibiting astrogliosis and inflammation in fructose-fed rats

(2014) Jian-Mei Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Effects of High-Fat Diet on Neuronal Damage, Gliosis, Inflammatory Process and Oxidative Stress in the Hippocampus Induced by Transient Cerebral Ischemia

(2014) Bing Chun Yan et al.   NEUROCHEMICAL RESEARCH

Astrocyte Reactivity and Reactive Astrogliosis: Costs and Benefits

(2014) Milos Pekny et al.   PHYSIOLOGICAL REVIEWS

Dynamic Localization of Glucokinase and Its Regulatory Protein in Hypothalamic Tanycytes

(2014) Magdiel Salgado et al.   PLoS One

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

(2014) Sung S. Choi et al.   PLoS One

Anti-Inflammatory Effects of Progesterone in Lipopolysaccharide-Stimulated BV-2 Microglia

(2014) Beilei Lei et al.   PLoS One

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes

(2014) Yue Wang et al.   PLoS One

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Hypothalamic PGC-1α Protects Against High-Fat Diet Exposure by Regulating ERα

(2014) Eugenia Morselli et al.   Cell Reports

Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice

(2014) Daniel A. Lee et al.   Frontiers in Neuroscience

Sex differences in the physiology of eating

(2013) Lori Asarian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting

(2013) Fanny Langlet et al.   Cell Metabolism

Hypothalamic Inflammation Without Astrogliosis in Response to High Sucrose Intake Is Modulated by Neonatal Nutrition in Male Rats

(2013) Esther Fuente-Martín et al.   ENDOCRINOLOGY

Hormones and diet, but not body weight, control hypothalamic microglial activity

(2013) Yuanqing Gao et al.   GLIA

Central expression and anorectic effect of brain-derived neurotrophic factor are regulated by circulating estradiol levels

(2013) Zheng Zhu et al.   HORMONES AND BEHAVIOR

Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity

(2013) Bhavaani Jayaram et al.   JOURNAL OF APPLIED PHYSIOLOGY

Differential effects of GH and GH-releasing peptide-6 on astrocytes

(2013) Eva Baquedano et al.   JOURNAL OF ENDOCRINOLOGY

Neuromedin U Partly Mimics Thyroid-Stimulating Hormone and Triggers Wnt/β-Catenin Signalling in the Photoperiodic Response of F344 Rats

(2013) G. Helfer et al.   JOURNAL OF NEUROENDOCRINOLOGY

Sex steroid hormone-mediated functional regulation of microglia-like BV-2 cells during hypoxia

(2013) Pardes Habib et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice

(2012) Mieke C. Louwe et al.   Applied Physiology Nutrition and Metabolism

Integrating Metabolism and Longevity Through Insulin and IGF1 Signaling

(2012) Marianna Sadagurski et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Increased Hypothalamic Inflammation Associated with the Susceptibility to Obesity in Rats Exposed to High-Fat Diet

(2012) Xiaoke Wang et al.   Experimental Diabetes Research

Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes

(2012) Esther Fuente-Martín et al.   JOURNAL OF CLINICAL INVESTIGATION

Regional astrogliosis in the mouse hypothalamus in response to obesity

(2012) Laura B. Buckman et al.   JOURNAL OF COMPARATIVE NEUROLOGY

GH and IGF1: Roles in Energy Metabolism of Long-Living GH Mutant Mice

(2012) H. M. Brown-Borg et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

(2012) Daniel A Lee et al.   NATURE NEUROSCIENCE

Exercise protects against high-fat diet-induced hypothalamic inflammation

(2012) Chun-Xia Yi et al.   PHYSIOLOGY & BEHAVIOR

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

(2011) Yong Xu et al.   Cell Metabolism

Differential Acute and Chronic Effects of Leptin on Hypothalamic Astrocyte Morphology and Synaptic Protein Levels

(2011) Cristina García-Cáceres et al.   ENDOCRINOLOGY

Estrogen modulates abdominal adiposity and protects female mice from obesity and impaired glucose tolerance

(2011) Renee E. Stubbins et al.   EUROPEAN JOURNAL OF NUTRITION

An in vitro experimental model of neuroinflammation: the induction of interleukin-6 in murine astrocytes infected with Theiler’s murine encephalomyelitis virus, and its inhibition by oestrogenic receptor modulators

(2011) Nazario Rubio et al.   IMMUNOLOGY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Sex differences in microglial colonization of the developing rat brain

(2011) Jaclyn M. Schwarz et al.   JOURNAL OF NEUROCHEMISTRY

Activation of Microglia in Specific Hypothalamic Nuclei and the Cerebellum of Adult Rats Exposed to Neonatal Overnutrition

(2011) S. Tapia-González et al.   JOURNAL OF NEUROENDOCRINOLOGY

Postnatal Overfeeding Leads to Obesity and Exacerbated Febrile Responses to Lipopolysaccharide Throughout Life

(2011) M. A. Clarke et al.   JOURNAL OF NEUROENDOCRINOLOGY

Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells

(2011) Raquel Ferreira et al.   Journal of Neuroinflammation

Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation

(2011) Yi-Fang Tu et al.   Journal of Neuroinflammation

Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats

(2011) Esther Fuente-Martín et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: The role of tumor necrosis factor-α

(2010) Yi Zhong et al.   BRAIN BEHAVIOR AND IMMUNITY

Metabolic impact of sex hormones on obesity

(2010) Lynda M. Brown et al.   BRAIN RESEARCH

Estradiol Increases the Anorectic Effect of Central Apolipoprotein A-IV

(2010) Ling Shen et al.   ENDOCRINOLOGY

Changes in Melanocortin Expression and Inflammatory Pathways in Fetal Offspring of Nonhuman Primates Fed a High-Fat Diet

(2010) B. E. Grayson et al.   ENDOCRINOLOGY

Contribution of glial-neuronal interactions to the neuroendocrine control of female puberty

(2010) Sergio R. Ojeda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Emerging new sites for adult neurogenesis in the mammalian brain: a comparative study between the hypothalamus and the classical neurogenic zones

(2010) Martine Migaud et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Enduring consequences of maternal obesity for brain inflammation and behavior of offspring

(2010) Staci D. Bilbo et al.   FASEB JOURNAL

Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour

(2010) María LLorens-Martín et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Inflammatory lipid mediators in adipocyte function and obesity

(2010) Abishek Iyer et al.   Nature Reviews Endocrinology

A high-fat diet impairs neurogenesis: Involvement of lipid peroxidation and brain-derived neurotrophic factor

(2010) Hee Ra Park et al.   NEUROSCIENCE LETTERS

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity induces functional astrocytic leptin receptors in hypothalamus

(2009) H. Hsuchou et al.   BRAIN

Leptin modulates cell morphology and cytokine release in microglia

(2009) Véronique Lafrance et al.   BRAIN BEHAVIOR AND IMMUNITY

Selective Estrogen Receptor Modulators Decrease Reactive Astrogliosis in the Injured Brain: Effects of Aging and Prolonged Depletion of Ovarian Hormones

(2009) George Barreto et al.   ENDOCRINOLOGY

Impact of diet on adult hippocampal neurogenesis

(2009) Doris Stangl et al.   Genes and Nutrition

Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-γ-inducible protein-10 by astrocytes exposed to inflammatory challengein vitro

(2009) M. Cerciat et al.   GLIA

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Neonatal bacterial infection alters fever to live and simulated infections in adulthood

(2009) Staci D. Bilbo et al.   PSYCHONEUROENDOCRINOLOGY

Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain

(2008) Zaman Mirzadeh et al.   Cell Stem Cell

Astrocyte Leptin Receptor (ObR) and Leptin Transport in Adult-Onset Obese Mice

(2008) Weihong Pan et al.   ENDOCRINOLOGY

Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs

(2008) Silvia Tapia-Gonzalez et al.   JOURNAL OF ENDOCRINOLOGY

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL

The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis

(2007) J.L. Trejo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE