Tumour tissue transport after intraperitoneal anticancer drug delivery

Vitamin D and Myofibroblasts in Fibrosis and Cancer: At Cross-purposes with TGF-β/SMAD Signaling

(2016) SHRAGA SHANY et al.   ANTICANCER RESEARCH

iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes

(2016) Lorena Simón-Gracia et al.   BIOMATERIALS

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer

(2016) S. R. Hingorani et al.   CLINICAL CANCER RESEARCH

Cisplatin binding to proteins: A structural perspective

(2016) Luigi Messori et al.   COORDINATION CHEMISTRY REVIEWS

Integrin-mediated mechanotransduction

(2016) Zhiqi Sun et al.   JOURNAL OF CELL BIOLOGY

The Tyrosine Kinase Inhibitor Imatinib Augments Extracellular Fluid Exchange and Reduces Average Collagen Fibril Diameter in Experimental Carcinoma

(2016) P. O. Olsson et al.   MOLECULAR CANCER THERAPEUTICS

A Phase I Study of FOLFIRINOX Plus IPI-926, a Hedgehog Pathway Inhibitor, for Advanced Pancreatic Adenocarcinoma

(2016) Andrew H. Ko et al.   PANCREAS

Survival and toxicity following sequential multimodality treatment including whole abdominopelvic radiotherapy for patients with desmoplastic small round cell tumor

(2016) Eleanor Marshall Osborne et al.   RADIOTHERAPY AND ONCOLOGY

Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma

(2016) Vidhya Kumar et al.   Translational Oncology

Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer

(2015) Tong Li et al.   CANCER RESEARCH

Exploring the Biomechanical Properties of Brain Malignancies and Their Pathologic Determinants In Vivo with Magnetic Resonance Elastography

(2015) Y. Jamin et al.   CANCER RESEARCH

Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors

(2015) Man Yu et al.   CANCER SCIENCE

A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis

(2015) Kazuki N. Sugahara et al.   JOURNAL OF CONTROLLED RELEASE

Tumor priming by Apo2L/TRAIL reduces interstitial fluid pressure and enhances efficacy of liposomal gemcitabine in a patient derived xenograft tumor model

(2015) Bonnie L. Hylander et al.   JOURNAL OF CONTROLLED RELEASE

Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)

(2015) E. Geretti et al.   MOLECULAR CANCER THERAPEUTICS

Ultrasound Elastography – Review of Techniques and its Clinical Applications

(2015) Urszula Zaleska-Dorobisz et al.   Advances in Clinical and Experimental Medicine

Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1

(2014) Y Akashi et al.   BRITISH JOURNAL OF CANCER

Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

(2014) Mara H. Sherman et al.   CELL

Modulation of the interstitial fluid pressure by high intensity focused ultrasound as a way to alter local fluid and solute movement: insights from a mathematical model

(2014) E Sassaroli et al.   PHYSICS IN MEDICINE AND BIOLOGY

Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model

(2014) Jean Yannis Perentes et al.   Translational Oncology

Intraperitoneal Chemotherapy of Peritoneal Carcinomatosis Using Pressurized Aerosol as an Alternative to Liquid Solution: First Evidence for Efficacy

(2013) Wiebke Solass et al.   ANNALS OF SURGICAL ONCOLOGY

Renal and Hepatic Toxicities After Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC)

(2013) Ana Blanco et al.   ANNALS OF SURGICAL ONCOLOGY

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC): Occupational Health and Safety Aspects

(2013) Wiebke Solaß et al.   ANNALS OF SURGICAL ONCOLOGY

Use of the Proton Pump Inhibitor Pantoprazole to Modify the Distribution and Activity of Doxorubicin: A Potential Strategy to Improve the Therapy of Solid Tumors

(2013) K. J. Patel et al.   CLINICAL CANCER RESEARCH

Activity of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) with cisplatin and doxorubicin in women with recurrent, platinum-resistant ovarian cancer: Preliminary clinical experience

(2013) Clemens B. Tempfer et al.   GYNECOLOGIC ONCOLOGY

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment

(2013) Edmond W. K. Young   Integrative Biology

Microfluidic technique to measure intratumoral transport and calculate drug efficacy shows that binding is essential for doxorubicin and release hampers Doxil

(2013) Bhushan J. Toley et al.   Integrative Biology

Optimization of Drug Delivery Systems for Intraperitoneal Therapy to Extend the Residence Time of the Chemotherapeutic Agent

(2013) L. De Smet et al.   TheScientificWorldJOURNAL

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

High Pressure Enhances the Effect of Hyperthermia in Intraperitoneal Chemotherapy With Oxaliplatin

(2012) Olivier Facy et al.   ANNALS OF SURGERY

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin-Positive Metastatic Human Melanoma Xenografts

(2012) M. Moschetta et al.   CANCER RESEARCH

Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors

(2012) Shutao Wang et al.   JOURNAL OF CONTROLLED RELEASE

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK

(2012) A-M Baker et al.   ONCOGENE

Hyperthermia and Intraperitoneal Chemotherapy for the Treatment of Peritoneal Carcinomatosis

(2011) Yvonne L. B. Klaver et al.   ANNALS OF SURGERY

Intraperitoneal clearance as a potential biomarker of cisplatin after intraperitoneal perioperative chemotherapy: a population pharmacokinetic study

(2011) B Royer et al.   BRITISH JOURNAL OF CANCER

Mild Elevation of Body Temperature Reduces Tumor Interstitial Fluid Pressure and Hypoxia and Enhances Efficacy of Radiotherapy in Murine Tumor Models

(2011) A. Sen et al.   CANCER RESEARCH

Collagenase-1 injection improved tumor distribution and gene expression of cationic lipoplex

(2011) Mako Kato et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis

(2011) Olivier Facy et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

(2011) B. Diop-Frimpong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraoperative chemotherapy with cisplatin and epinephrine after cytoreductive surgery in patients with recurrent ovarian cancer: a phase I study

(2010) Emmanuel Guardiola et al.   ANTI-CANCER DRUGS

Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

(2010) K. N. Sugahara et al.   SCIENCE

Multiscale Measurements Distinguish Cellular and Interstitial Hindrances to Diffusion In Vivo

(2009) Vikash P. Chauhan et al.   BIOPHYSICAL JOURNAL

Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

(2009) Ingrid Moen et al.   BMC CANCER

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts

(2009) Jean Y Perentes et al.   NATURE METHODS

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Tumor-Penetrating Microparticles for Intraperitoneal Therapy of Ovarian Cancer

(2008) Z. Lu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies

(2008) Raja Venkatasubramanian et al.   JOURNAL OF THEORETICAL BIOLOGY

Antineoplastic agents in the management of ovarian cancer: current status and emerging therapeutic strategies

(2008) Maurie Markman   TRENDS IN PHARMACOLOGICAL SCIENCES

Pulsed High Intensity Focused Ultrasound Mediated Nanoparticle Delivery: Mechanisms and Efficacy in Murine Muscle

(2008) Brian E. O'Neill et al.   ULTRASOUND IN MEDICINE AND BIOLOGY