T-cell regulation through a basic suppressive mechanism targeting low-density lipoprotein receptor-related protein 1

Methotrexate and its therapeutic antagonists caffeine and theophylline, target a motogenic T-cell mechanism driven by thrombospondin-1 (TSP-1)

(2016) Toomas Talme et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors

(2015) Sten-Erik Bergström et al.   IMMUNOLOGY

TSP-1 Deficiency Alters Ocular Microbiota: Implications for Sjögren's Syndrome Pathogenesis

(2015) Marielle Terzulli et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CD47-Independent Effects Mediated by the TSP-Derived 4N1K Peptide

(2014) Pascal Leclair et al.   PLoS One

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cytokine-controlled mechanism for integrated regulation of T-lymphocyte motility, adhesion and activation

(2013) Sten-Erik Bergström et al.   IMMUNOLOGY

Regulation of T-lymphocyte motility, adhesion and de-adhesion by a cell surface mechanism directed by low density lipoprotein receptor-related protein 1 and endogenous thrombospondin-1

(2013) Toomas Talme et al.   IMMUNOLOGY

The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms

(2013) Michael J. Ophir et al.   JOURNAL OF CELL BIOLOGY

CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions

(2013) Veronica Azcutia et al.   MOLECULAR BIOLOGY OF THE CELL

Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma

(2013) Elizabeth E. Gerber et al.   NATURE

Differential Surface Expression of ADAM10 and ADAM17 on Human T Lymphocytes and Tumor Cells

(2013) Henriette Ebsen et al.   PLoS One

Peripheral Tissue Homing Receptor Control of Naïve, Effector, and Memory CD8 T Cell Localization in Lymphoid and Non-Lymphoid Tissues

(2013) C. Colin Brinkman et al.   Frontiers in Immunology

Inside-out, outside-in, and inside–outside-in: G protein signaling in integrin-mediated cell adhesion, spreading, and retraction

(2012) Bo Shen et al.   CURRENT OPINION IN CELL BIOLOGY

Chemokines and the Signaling Modules Regulating Integrin Affinity

(2012) Alessio Montresor et al.   Frontiers in Immunology

The Unfolded Protein Response Is a Major Mechanism by Which LRP1 Regulates Schwann Cell Survival after Injury

(2011) E. Mantuano et al.   JOURNAL OF NEUROSCIENCE

Staying Alive: T Cell Costimulation, CD28, and Bcl-xL

(2010) T. H. Watts   JOURNAL OF IMMUNOLOGY

Cutting Edge: Mechanisms of IL-2-Dependent Maintenance of Functional Regulatory T Cells

(2010) L. Barron et al.   JOURNAL OF IMMUNOLOGY

Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

(2010) Matvey Gorovoy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Thrombospondin-1: a unique marker to identify in vitro platelet activation when monitoring in vivo processes

(2010) P. STARLINGER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A CD26-Controlled Cell Surface Cascade for Regulation of T Cell Motility and Chemokine Signals

(2009) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

Heat shock proteins and immune system

(2009) Min-Fu Tsan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

LRP1 shedding in human brain: roles of ADAM10 and ADAM17

(2009) Qiang Liu et al.   Molecular Neurodegeneration

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY

Enhanced Allograft Survival and Modulation of T-Cell Alloreactivity Induced by Inhibition of MMP/ADAM Enzymatic Activity

(2008) V. L. Eaton et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CXCL12 (SDF-1α) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

(2008) Moran Meiron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS