Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma

Functions of TGF-β-Exposed Plasmacytoid Dendritic Cells

(2013) Philippe Saas et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Matrix-dependent perturbation of TGFβ signaling and disease

(2012) Jefferson J. Doyle et al.   FEBS LETTERS

Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma

(2011) Flavia V. Castelino et al.   ARTHRITIS AND RHEUMATISM

Lessons on the pathogenesis of aneurysm from heritable conditions

(2011) Mark E. Lindsay et al.   NATURE

CCN2 Is Required for the TGF-β Induced Activation of Smad1 - Erk1/2 Signaling Network

(2011) Sashidhar S. Nakerakanti et al.   PLoS One

Cross Talk among TGF-  Signaling Pathways, Integrins, and the Extracellular Matrix

(2011) J. S. Munger et al.   Cold Spring Harbor Perspectives in Biology

Differential development of plasmacytoid dendritic cells in Th1- and Th2-like cytokine milieus

(2010) K. Bratke et al.   ALLERGY

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

(2010) Britta Maurer et al.   ARTHRITIS AND RHEUMATISM

Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance

(2010) Melissa Swiecki et al.   IMMUNOLOGICAL REVIEWS

Type I interferons: crucial participants in disease amplification in autoimmunity

(2010) John C. Hall et al.   Nature Reviews Rheumatology

Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome

(2010) B. L. Loeys et al.   Science Translational Medicine

Loss of β1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model

(2009) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

Plasmacytoid Dendritic Cells Regulate Autoreactive B Cell Activation via Soluble Factors and in a Cell-to-Cell Contact Manner

(2009) C. Ding et al.   JOURNAL OF IMMUNOLOGY

Transforming growth factor β as a therapeutic target in systemic sclerosis

(2009) John Varga et al.   Nature Reviews Rheumatology

Heparan sulfate–dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts

(2008) Yunliang Chen et al.   ARTHRITIS AND RHEUMATISM

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

(2008) Valérie Dardalhon et al.   NATURE IMMUNOLOGY

Capillary Regeneration in Scleroderma: Stem Cell Therapy Reverses Phenotype?

(2008) Jo N. Fleming et al.   PLoS One

PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon

(2008) H. Watarai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA