The immunogenetics of neurological disease

KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation

(2017) Jeanette E. Boudreau et al.   JOURNAL OF CLINICAL ONCOLOGY

HLA-DRA/HLA-DRB5 polymorphism affects risk of sporadic ALS and survival in a southwest Chinese cohort

(2017) Xinglong Yang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

HLA and age of onset in myasthenia gravis

(2017) Ernestina Santos et al.   NEUROMUSCULAR DISORDERS

Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study

(2017) Natasha Z. R. Steele et al.   PLOS MEDICINE

Identification of rare genetic variation of NLRP1 gene in familial multiple sclerosis

(2017) Ales Maver et al.   Scientific Reports

Gene-based aggregate SNP associations between candidate AD genes and cognitive decline

(2016) Jasmine Nettiksimmons et al.   AGE

The killer immunoglobulin-like receptor KIR3DL1 in combination with HLA-Bw4 is protective against multiple sclerosis in African Americans

(2016) J A Hollenbach et al.   GENES AND IMMUNITY

Genetic associations of killer immunoglobulin like receptors and class I human leukocyte antigens on childhood acute lymphoblastic leukemia among north Indians

(2016) Maneesh Kumar Misra et al.   HUMAN IMMUNOLOGY

Increased occurrence of anti-AQP4 seropositivity and unique HLA Class II associations with neuromyelitis optica (NMO), among Muslim Arabs in Israel

(2016) Livnat Brill et al.   JOURNAL OF NEUROIMMUNOLOGY

HLA-A2 Alleles Mediate Alzheimer’s Disease by Altering Hippocampal Volume

(2016) Zi-Xuan Wang et al.   MOLECULAR NEUROBIOLOGY

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

(2016) SungWon Song et al.   NATURE MEDICINE

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

(2016) Jennifer S. Yokoyama et al.   JAMA Neurology

Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci

(2016) Celeste M. Karch et al.   PLoS One

Genome-wide association study of schizophrenia in Ashkenazi Jews

(2015) Fernando S. Goes et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis

(2015) An Goris et al.   BRAIN

A bird's eye view of NK cell receptor interactions with their MHC class I ligands

(2015) Philippa M. Saunders et al.   IMMUNOLOGICAL REVIEWS

The immunogenetics of multiple sclerosis: A comprehensive review

(2015) Jill A. Hollenbach et al.   JOURNAL OF AUTOIMMUNITY

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(2015) Michael Seldin et al.   MOLECULAR MEDICINE

Brca1 is expressed in human microglia and is dysregulated in human and animal model of ALS

(2015) Harun Najib Noristani et al.   Molecular Neurodegeneration

Building global capacity for brain and nervous system disorders research

(2015) Linda B. Cottler et al.   NATURE

Class II HLA interactions modulate genetic risk for multiple sclerosis

(2015) Loukas Moutsianas et al.   NATURE GENETICS

The HLA-B*4601-DRB1*0901 haplotype is positively correlated with juvenile ocular myasthenia gravis in a southern Chinese Han population

(2015) Hui-yu Feng et al.   NEUROLOGICAL SCIENCES

Selector function of MHC I molecules is determined by protein plasticity

(2015) Alistair Bailey et al.   Scientific Reports

A Genome-Wide Association Study of Myasthenia Gravis

(2015) Alan E. Renton et al.   JAMA Neurology

Association of Brain DNA Methylation inSORL1,ABCA7,HLA-DRB5,SLC24A4, andBIN1With Pathological Diagnosis of Alzheimer Disease

(2015) Lei Yu et al.   JAMA Neurology

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

(2015) Inge R Holtman et al.   Acta Neuropathologica Communications

Polygenic Analysis of Late-Onset Alzheimer’s Disease from Mainland China

(2015) Bin Jiao et al.   PLoS One

High frequency of DQB1*05 and absolute absence of DRB1*13 in muscle-specific tyrosine kinase positive myasthenia gravis

(2014) A. V. Nikolic et al.   EUROPEAN JOURNAL OF NEUROLOGY

HLA-DRAis associated with Parkinson's disease in Iranian population

(2014) J. Jamshidi et al.   International Journal of Immunogenetics

HLA-DRArs3129882 A/G polymorphism was not a risk factor for Parkinson's disease in Chinese-based populations: a meta-analysis

(2014) Ze-Gang Ma et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

(2014) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Maternal KIR in Combination with Paternal HLA-C2 Regulate Human Birth Weight

(2014) S. E. Hiby et al.   JOURNAL OF IMMUNOLOGY

Donor Killer Cell Ig-like Receptor B Haplotypes, Recipient HLA-C1, and HLA-C Mismatch Enhance the Clinical Benefit of Unrelated Transplantation for Acute Myelogenous Leukemia

(2014) S. Cooley et al.   JOURNAL OF IMMUNOLOGY

The role of KIR2DS1 in multiple sclerosis - KIR in Portuguese MS patients

(2014) Andreia Bettencourt et al.   JOURNAL OF NEUROIMMUNOLOGY

Synapse elimination and learning rules co-regulated by MHC class I H2-Db

(2014) Hanmi Lee et al.   NATURE

The global burden of neurologic diseases

(2014) J. H. Chin et al.   NEUROLOGY

Are KIR and HLA class I genes associated with schizophrenia?

(2014) A. Wiśniewski et al.   TISSUE ANTIGENS

Effects of Peptide on NK Cell-Mediated MHC I Recognition

(2014) Sorcha A. Cassidy et al.   Frontiers in Immunology

Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region

(2013) William T. Wissemann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The role of inflammation in sporadic and familial Parkinson’s disease

(2013) Michela Deleidi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autoimmune myasthenia gravis

(2013) Rozen Le Panse et al.   CURRENT OPINION IN NEUROLOGY

Association of HLA-DRB1∗14, -DRB1∗16 and -DQB1∗05 with MuSK-myasthenia gravis in patients from Turkey

(2013) Mahdi Alahgholi-Hajibehzad et al.   HUMAN IMMUNOLOGY

Inflammation in neurodegenerative diseases - an update

(2013) Sandra Amor et al.   IMMUNOLOGY

Genetic basis of myasthenia gravis – A comprehensive review

(2013) Nili Avidan et al.   JOURNAL OF AUTOIMMUNITY

Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis

(2013) Hanne F Harbo et al.   Multiple Sclerosis Journal

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Genetic risk variants in African Americans with multiple sclerosis

(2013) N. Isobe et al.   NEUROLOGY

Oligoclonal Band Status in Scandinavian Multiple Sclerosis Patients Is Associated with Specific Genetic Risk Alleles

(2013) Inger-Lise Mero et al.   PLoS One

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

(2013) Nikolaos A. Patsopoulos et al.   PLoS Genetics

Gene expression profiling by mRNA sequencing reveals increased expression of immune/inflammation-related genes in the hippocampus of individuals with schizophrenia

(2013) Y Hwang et al.   Translational Psychiatry

Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss

(2012) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Risk for myasthenia gravis maps to a151Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08

(2012) Peter K. Gregersen et al.   ANNALS OF NEUROLOGY

Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia

(2012)   BIOLOGICAL PSYCHIATRY

CD8 T cells express randomly selected KIRs with distinct specificities compared with NK cells

(2012) N. K. Bjorkstrom et al.   BLOOD

Natural killer cells and their receptors in multiple sclerosis

(2012) Gurman Kaur et al.   BRAIN

Association of HLA-DR/DQ polymorphism with myasthenia gravis in Tunisian patients

(2012) Najiba Fekih-Mrissa et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Analysis of Copy Number Variation in Alzheimer’s Disease: The NIALOAD/ NCRAD Family Study

(2012) Shanker Swaminathan et al.   Current Alzheimer Research

Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes

(2012) Simone de Jong et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Animal models of Parkinson’s disease

(2012) Fabio Blandini et al.   FEBS Journal

Killer cell immunoglobulin-like receptor (KIR) gene content variation in the HGDP-CEPH populations

(2012) Jill A. Hollenbach et al.   IMMUNOGENETICS

HLA-DQA1*03:02/DQB1*03:03:02 is strongly associated with susceptibility to childhood-onset ocular myasthenia gravis in Southern Han Chinese

(2012) Wen-Hua Zhu et al.   JOURNAL OF NEUROIMMUNOLOGY

Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin 4 antibody status

(2012) Satoshi Yoshimura et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A Novel Variant Marking HLA-DP Expression Levels Predicts Recovery from Hepatitis B Virus Infection

(2012) R. Thomas et al.   JOURNAL OF VIROLOGY

Association between Parkinson's disease and the HLA-DRB1 locus

(2012) Ismaïl Ahmed et al.   MOVEMENT DISORDERS

Whole-genome and whole-exome sequencing in neurological diseases

(2012) Jia-Nee Foo et al.   Nature Reviews Neurology

Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population

(2012) Angelina H. Maniaol et al.   PLoS One

HLA-DRB1 Alleles Are Associated with the Susceptibility to Sporadic Parkinson’s Disease in Chinese Han Population

(2012) Congcong Sun et al.   PLoS One

Genetic and Infectious Profiles of Japanese Multiple Sclerosis Patients

(2012) Satoshi Yoshimura et al.   PLoS One

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: Associations and functional implications

(2012) Monojit Debnath et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

MHC-Resident Variation Affects Risks After Unrelated Donor Hematopoietic Cell Transplantation

(2012) E. W. Petersdorf et al.   Science Translational Medicine

HLA/KIR Restraint of HIV: Surviving the Fittest

(2011) Arman A. Bashirova et al.   Annual Review of Immunology

Genome-Wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population

(2011) Xinmin Liu et al.   BMC Medical Genetics

Association between HLA-DRB1 and myasthenia gravis in a northern Han Chinese population

(2011) Yan-chen Xie et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

Killer cell immunoglobulin-like receptor genes in Spanish multiple sclerosis patients

(2011) Juan A. García-León et al.   MOLECULAR IMMUNOLOGY

Killer immunoglobulin-like receptor locus polymorphisms in multiple sclerosis

(2011) Ilijas Jelčić et al.   Multiple Sclerosis Journal

Differential microRNA regulation of HLA-C expression and its association with HIV control

(2011) Smita Kulkarni et al.   NATURE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

(2011) Wei-Hua Yue et al.   NATURE GENETICS

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

HLA rs3129882 variant in Chinese Han patients with late-onset sporadic Parkinson disease

(2011) Yi Guo et al.   NEUROSCIENCE LETTERS

Human leukocyte antigen variation and Parkinson’s disease

(2011) Andreas Puschmann et al.   PARKINSONISM & RELATED DISORDERS

Promise and pitfalls of the Immunochip

(2011) Adrian Cortes et al.   ARTHRITIS RESEARCH & THERAPY

Copy Number Variation of KIR Genes Influences HIV-1 Control

(2011) Kimberly Pelak et al.   PLOS BIOLOGY

Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease

(2011) Chuong B. Do et al.   PLoS Genetics

Genome-Wide Association Study of Schizophrenia in a Japanese Population

(2010) Masashi Ikeda et al.   BIOLOGICAL PSYCHIATRY

Central nervous system (CNS)–resident natural killer cells suppress Th17 responses and CNS autoimmune pathology

(2010) Junwei Hao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

KIRs and their HLA ligands in Remitting–Relapsing Multiple Sclerosis

(2010) Caterina Fusco et al.   JOURNAL OF NEUROIMMUNOLOGY

HLA-DPB1*0501 is associated with susceptibility to anti-aquaporin-4 antibodies positive neuromyelitis optica in Southern Han Chinese

(2010) Honghao Wang et al.   JOURNAL OF NEUROIMMUNOLOGY

Association of the human leucocyte antigen region with susceptibility to Parkinson's disease

(2010) M. Saiki et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Different HLA class II (DRB1 and DQB1) alleles determine either susceptibility or resistance to NMO and multiple sclerosis among the French Afro-Caribbean population

(2010) R Deschamps et al.   Multiple Sclerosis Journal

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

Allele frequency net: a database and online repository for immune gene frequencies in worldwide populations

(2010) F. F. Gonzalez-Galarza et al.   NUCLEIC ACIDS RESEARCH

Peptide antagonism as a mechanism for NK cell activation

(2010) L. Fadda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HL-A Antigens and Multiple Sclerosis

(2010) J. BERTRAMS et al.   TISSUE ANTIGENS

Multiple Sclerosis: Association with HL-A3

(2010) S. NAITO et al.   TISSUE ANTIGENS

Polio Antibodies and HLA Antigens in Amyotrophic Lateral Sclerosis

(2010) Matti Jokelainen et al.   TISSUE ANTIGENS

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis

(2009) Åslaug R. Lorentzen et al.   ANNALS OF NEUROLOGY

Regulation of human NK-cell cytokine and chemokine production by target cell recognition

(2009) C. Fauriat et al.   BLOOD

Susceptibility to Crohn’s disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand

(2009) Jill A. Hollenbach et al.   IMMUNOGENETICS

The HLA genomic loci map: expression, interaction, diversity and disease

(2009) Takashi Shiina et al.   JOURNAL OF HUMAN GENETICS

Influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis in Japanese patients with respect to anti-aquaporin 4 antibody status

(2009) N. Isobe et al.   Multiple Sclerosis Journal

Is neuromyelitis optica associated with human leukocyte antigen?

(2009) H Zéphir et al.   Multiple Sclerosis Journal

HLA-DRB association in neuromyelitis optica is different from that observed in multiple sclerosis

(2009) Doralina Guimaraães Brum et al.   Multiple Sclerosis Journal

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

(2009) Yoichiro Kamatani et al.   NATURE GENETICS

HLA class II allele analysis in MuSK-positive myasthenia gravis suggests a role for DQ5

(2009) E. Bartoccioni et al.   NEUROLOGY

MHC Class I: An Unexpected Role in Neuronal Plasticity

(2009) Carla J. Shatz   NEURON

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility

(2009) M. R. Lincoln et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

(2009) et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of theHLA-DPB1*0501allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders

(2009) T. Matsushita et al.   TISSUE ANTIGENS

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

Genotype–Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures

(2008) D. T. Okuda et al.   BRAIN

Association of the HLA-DRB1 alleles with characteristic MRI features of Asian multiple sclerosis

(2008) T Matsuoka et al.   Multiple Sclerosis Journal

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS

(2008) I. M. Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Yin and Yang of HLA and KIR in human disease

(2008) Smita Kulkarni et al.   SEMINARS IN IMMUNOLOGY

Natural killer cells of Parkinson's disease patients are set up for activation: A possible role for innate immunity in the pathogenesis of this disease

(2007) Tomoko Mihara et al.   PARKINSONISM & RELATED DISORDERS