The role of KIR and HLA interactions in pregnancy complications

Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes

(2016) Michelle M. Clark et al.   HUMAN HEREDITY

Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution

(2016) Bridget S. Penman et al.   IMMUNOGENETICS

A vision of KIR variation at super resolution

(2016) John A Hammond et al.   IMMUNOLOGY

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology

(2016) Vivien Béziat et al.   IMMUNOLOGY

Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy

(2016) Philippa R. Kennedy et al.   JOURNAL OF IMMUNOLOGY

HLA-CandKIRcombined genotype as new response marker for HBeAg-positive chronic hepatitis B patients treated with interferon-based combination therapy

(2016) F. Stelma et al.   JOURNAL OF VIRAL HEPATITIS

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

(2016) Wilfredo F Garcia-Beltran et al.   NATURE IMMUNOLOGY

Variation of maternal KIR and fetal HLA-C genes in reproductive failure: too early for clinical intervention

(2016) Ashley Moffett et al.   REPRODUCTIVE BIOMEDICINE ONLINE

HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1

(2016) Aura Burian et al.   PLoS One

Recurrence of hypertensive disorders of pregnancy: an individual patient data metaanalysis

(2015) Miriam F. van Oostwaard et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Recurrent Pregnancy Loss in Women with Killer Cell Immunoglobulin-Like Receptor KIR2DS1 is Associated with an Increased HLA-C2 Allelic Frequency

(2015) Svetlana V. Dambaeva et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

First do no harm: uterine natural killer (NK) cells in assisted reproduction

(2015) A. Moffett et al.   HUMAN REPRODUCTION

Co-evolution of NK receptors and HLA ligands in humans is driven by reproduction

(2015) Ashley Moffett et al.   IMMUNOLOGICAL REVIEWS

Tissue-Specific Education of Decidual NK Cells

(2015) Andrew M. Sharkey et al.   JOURNAL OF IMMUNOLOGY

AKIR Bcentromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

(2015) Annettee Nakimuli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal uterine natural killer cells nurture fetal growth: in medio stat virtus

(2015) Francesco Colucci et al.   TRENDS IN MOLECULAR MEDICINE

Natural cytotoxicity receptor splice variants orchestrate the distinct functions of human natural killer cell subtypes

(2015) Johan Siewiera et al.   Nature Communications

Maternal KIR haplotype influences live birth rate after double embryo transfer in IVF cycles in patients with recurrent miscarriages and implantation failure

(2014) D. Alecsandru et al.   HUMAN REPRODUCTION

The biology of NK cells and their receptors affects clinical outcomes after hematopoietic cell transplantation (HCT)

(2014) Bree Foley et al.   IMMUNOLOGICAL REVIEWS

Uterine NK cells: active regulators at the maternal-fetal interface

(2014) Ashley Moffett et al.   JOURNAL OF CLINICAL INVESTIGATION

Killer Ig-Like Receptor Expression in Uterine NK Cells Is Biased toward Recognition of HLA-C and Alters with Gestational Age

(2014) A. M. Sharkey et al.   JOURNAL OF IMMUNOLOGY

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

(2014) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Maternal KIR in Combination with Paternal HLA-C2 Regulate Human Birth Weight

(2014) S. E. Hiby et al.   JOURNAL OF IMMUNOLOGY

Diversity of Killer Cell Immunoglobulin-Like Receptor (KIR) Genotypes and KIR2DL2/3 Variants in HCV Treatment Outcome

(2014) Jose Ramón Vidal-Castiñeira et al.   PLoS One

Enhanced natural killer-cell and T-cell responses to influenza A virus during pregnancy

(2014) Alexander W. Kay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling

(2014) Jens Kieckbusch et al.   Nature Communications

Regulatory T-Cells in Pregnancy: Historical Perspective, State of the Art, and Burning Questions

(2014) Maria Grazia Ruocco et al.   Frontiers in Immunology

Pregnancy, parturition and preeclampsia in women of African ancestry

(2013) Annettee Nakimuli et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Maternal uterine NK cell–activating receptor KIR2DS1 enhances placentation

(2013) Shiqiu Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

NK Cell Tolerance of Self-Specific Activating Receptor KIR2DS1 in Individuals with Cognate HLA-C2 Ligand

(2013) G. Pittari et al.   JOURNAL OF IMMUNOLOGY

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors

(2012) W. Jiang et al.   GENOME RESEARCH

Evaluation of KIR genes in recurrent miscarriage

(2012) Ozlem Goruroglu Ozturk et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Mutation at Positively Selected Positions in the Binding Site for HLA-C Shows That KIR2DL1 Is a More Refined but Less Adaptable NK Cell Receptor Than KIR2DL3

(2012) H. G. Hilton et al.   JOURNAL OF IMMUNOLOGY

Secular trends in the epidemiology of pre-eclampsia throughout 40 years in Norway: prevalence, risk factors and perinatal survival

(2012) Kari Klungsøyr et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Significant Association of KIR2DL3-HLA-C1 Combination with Cerebral Malaria and Implications for Co-evolution of KIR and HLA

(2012) Kouyuki Hirayasu et al.   PLoS Pathogens

Characterizing the Pregnancy Immune Phenotype: Results of the Viral Immunity and Pregnancy (VIP) Study

(2011) Thomas A. Kraus et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Maternal KIR and fetal HLA-C: a fine balance

(2011) Olympe Chazara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Killer immunoglobulin-like receptors (KIRs) and HLA-C allorecognition patterns implicative of dominant activation of natural killer cells contribute to recurrent miscarriages

(2010) R. M. Faridi et al.   HUMAN REPRODUCTION

Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2

(2010) Susan E. Hiby et al.   JOURNAL OF CLINICAL INVESTIGATION

Pregnancy immunogenetics: NK cell education in the womb?

(2010) Peter Parham et al.   JOURNAL OF CLINICAL INVESTIGATION

ORIGINAL ARTICLE: Activating Killer Cell Immunoglobulin-Like Receptor Genes’ Association with Recurrent Miscarriage

(2009) Rafael Gustavo Vargas et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex

(2009) James A. Traherne et al.   HUMAN MOLECULAR GENETICS

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages

(2009) A. Moffett et al.   HUMAN REPRODUCTION

Fetal–maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells

(2009) Tamara Tilburgs et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

(2009) Rasmi Thomas et al.   NATURE GENETICS

Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study

(2009) S. Hernandez-Diaz et al.   BMJ-British Medical Journal

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

(2008) S. Cooley et al.   BLOOD

Natural-killer cell ligands at the maternal-fetal interface: UL-16 binding proteins, MHC class-I chain related molecules, HLA-F and CD48

(2008) R. Apps et al.   HUMAN REPRODUCTION

Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage

(2008) S.E. Hiby et al.   HUMAN REPRODUCTION

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies

(2008) Richard Apps et al.   IMMUNOLOGY