4.6 Review

A vision of KIR variation at super resolution

Journal

IMMUNOLOGY
Volume 148, Issue 3, Pages 249-252

Publisher

WILEY-BLACKWELL
DOI: 10.1111/imm.12606

Keywords

inhibitory; activating receptors; killer cell immunoglobulin-like receptors; natural killer cells

Categories

Funding

  1. Frederick National Laboratory for Cancer Research [HHSN261200800001E]
  2. Intramural Research Program of the NIH, Frederick National Laboratory, Center for Cancer Research
  3. Biotechnology and Biological Sciences Research Council Institute Strategic Program on Livestock Viral Diseases awarded
  4. Biotechnology and Biological Sciences Research Council [BBS/E/I/00001710] Funding Source: researchfish
  5. Medical Research Council [G1001738] Funding Source: researchfish
  6. BBSRC [BBS/E/I/00001710] Funding Source: UKRI
  7. MRC [G1001738] Funding Source: UKRI

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The Ninth Killer Cell Immunoglobulin-Like Receptor (KIR) Workshop was held in Winchester, UK late in the summer of 2015. The extraordinary diversity of KIR and its functional consequences were key themes throughout the meeting. Novel sequencing technologies and new bioinformatics techniques continue to increase our understanding of the genetic diversity and evolution of the KIR; while a deeper understanding of KIR functions, including their specificity for MHC and its peptide ligands, are generating more refined models of their role in disease. Limited to 100 delegates from around the world, this intimate workshop facilitated vigorous discussion, generating new ideas for research in this ever-expanding field.

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