Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance

The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors

(2016) Hannah Smith et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MicroRNA-320 family is downregulated in colorectal adenoma and affects tumor proliferation by targeting CDK6

(2016) Toshihiro Tadano et al.   World Journal of Gastrointestinal Oncology

miR-320 enhances the sensitivity of human colon cancer cells to chemoradiotherapy in vitro by targeting FOXM1

(2015) Lu-Ying Wan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis

(2015) C Blick et al.   BRITISH JOURNAL OF CANCER

MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer

(2015) Xin Yu et al.   CELL PROLIFERATION

MicroRNA-21 predicts response to preoperative chemoradiotherapy in locally advanced rectal cancer

(2015) Cristina Caramés et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

MicroRNA-494 sensitizes colon cancer cells to fluorouracil through regulation of DPYD

(2015) Jie Chai et al.   IUBMB LIFE

Metabolic Youth in Middle Age: Predicting Aging in Caenorhabditis elegans Using Metabolomics

(2015) Sarah K. Davies et al.   JOURNAL OF PROTEOME RESEARCH

MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer

(2015) Lin Zheng et al.   Journal of Translational Medicine

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

(2015) Haiquan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxic signature of microRNAs in glioblastoma: insights from small RNA deep sequencing

(2014) Rahul Agrawal et al.   BMC GENOMICS

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

(2014) D. Mouradov et al.   CANCER RESEARCH

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

(2014) Carme Camps et al.   Molecular Cancer

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

(2014) H Choudhry et al.   ONCOGENE

Hypoxia-Inducible MiR-210 Is an Independent Prognostic Factor and Contributes to Metastasis in Colorectal Cancer

(2014) Ailin Qu et al.   PLoS One

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

(2014) Twan van den Beucken et al.   Nature Communications

Critical Role of Aberrant Angiogenesis in the Development of Tumor Hypoxia and Associated Radioresistance

(2014) Gabriele Multhoff et al.   Cancers

HypoxamiRs and Cancer: From Biology to Targeted Therapy

(2013) Harriet E. Gee et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro

(2013) Jun Deng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

Methods of overcoming treatment resistance in colorectal cancer

(2013) Sally Temraz et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

(2013) Hani Choudhry et al.   EMBO REPORTS

Hypoxia: A master regulator of microRNA biogenesis and activity

(2013) Shriram Nallamshetty et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prognostic Value and Clinicopathological Differences of HIFs in Colorectal Cancer: Evidence from Meta-Analysis

(2013) Zhigang Chen et al.   PLoS One

Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells

(2012) Ken Kurokawa et al.   JOURNAL OF GASTROENTEROLOGY

HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5

(2012) Ainara Elorza et al.   MOLECULAR CELL

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

miR-210: The Master Hypoxamir

(2011) YUK C. CHAN et al.   MICROCIRCULATION

Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

(2011) Christian Frezza et al.   PLoS One

Gene expression and hypoxia in breast cancer

(2011) Elena Favaro et al.   Genome Medicine

HIF1A Overexpression Is Associated with Poor Prognosis in a Cohort of 731 Colorectal Cancers

(2010) Yoshifumi Baba et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)

(2010) N. Valeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

Metabolomic Profiling of Anionic Metabolites by Capillary Electrophoresis Mass Spectrometry

(2009) Tomoyoshi Soga et al.   ANALYTICAL CHEMISTRY

Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer

(2009) E Korkeila et al.   BRITISH JOURNAL OF CANCER

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover

(2008) Carsten Denkert et al.   Molecular Cancer