Gene expression and hypoxia in breast cancer

Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4

(2011) Saskia E Rademakers et al.   BMC CANCER

Molecular Imaging of Hypoxia

(2011) S. K. Chitneni et al.   JOURNAL OF NUCLEAR MEDICINE

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

miR-495 is upregulated by E12/E47 in breast cancer stem cells and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1

(2011) W W Hwang-Verslues et al.   ONCOGENE

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

(2010) F M Buffa et al.   BRITISH JOURNAL OF CANCER

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer

(2010) Antonis Giannakakis et al.   CANCER BIOLOGY & THERAPY

Antisense HIF-1α prevents acquired tumor resistance to angiostatin gene therapy

(2010) X Sun et al.   CANCER GENE THERAPY

MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT

(2010) Zhan Zhang et al.   CELL CYCLE

MicroRNA-210: A unique and pleiotropic hypoxamir

(2010) Stephen Y. Chan et al.   CELL CYCLE

PET imaging of hypoxia using [18F]HX4: a phase I trial

(2010) Judith van Loon et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

(2010) Z Chen et al.   ONCOGENE

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU

(2010) Elena Favaro et al.   PLoS One

MicroRNA Regulation of DNA Repair Gene Expression in Hypoxic Stress

(2009) M. E. Crosby et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNAs and Cancer: Short RNAs Go a Long Way

(2009) Andrea Ventura et al.   CELL

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

(2009) Stephen Y. Chan et al.   Cell Metabolism

Initial results of hypoxia imaging using 1-α-d-(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole (18F-FAZA)

(2009) Ernst J. Postema et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

miR-210 promotes osteoblastic differentiation through inhibition ofAcvR1b

(2009) Yosuke Mizuno et al.   FEBS LETTERS

Ischemic Preconditioning Augments Survival of Stem Cells via miR-210 Expression by Targeting Caspase-8-associated Protein 2

(2009) Ha Won Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Integrated Approach for Experimental Target Identification of Hypoxia-induced miR-210

(2009) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis

(2009) Adrian M. Jubb et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

(2009) A. Rapisarda et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Lactate Dehydrogenase 5 Expression in Squamous Cell Head and Neck Cancer Relates to Prognosis following Radical or Postoperative Radiotherapy

(2009) Michael I. Koukourakis et al.   ONCOLOGY

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

(2008) Charles H. Lawrie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hypoxia-Inducible Factor-2  Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer

(2008) K. Helczynska et al.   CANCER RESEARCH

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

(2008) C. Camps et al.   CLINICAL CANCER RESEARCH

MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer

(2008) Marilena V. Iorio et al.   EUROPEAN JOURNAL OF CANCER

Hypoxia induces microRNA miR-210 in vitro and in vivo

(2008) Kati Pulkkinen et al.   FEBS LETTERS

Serum and Tissue LDH Levels in Patients with Breast/Gynaecological Cancer and Benign Diseases

(2008) Michael I. Koukourakis et al.   GYNECOLOGIC AND OBSTETRIC INVESTIGATION

MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3

(2008) Pasquale Fasanaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated With Bevacizumab and Irinotecan

(2008) Sith Sathornsumetee et al.   JOURNAL OF CLINICAL ONCOLOGY

Phosphorylated ERα, HIF-1α, and MAPK Signaling As Predictors of Primary Endocrine Treatment Response and Resistance in Patients With Breast Cancer

(2008) Daniele Generali et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1 

(2008) M. Y. Koh et al.   MOLECULAR CANCER THERAPEUTICS

A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1 

(2008) S. H. Li et al.   MOLECULAR CANCER THERAPEUTICS

Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer

(2008) J. A. Foekens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers

(2008) Julia Ling-Yu Chen et al.   PLoS Genetics