Efficacy and Safety of Saffron Supplementation: Current Clinical Findings

Safranal Treatment Improves Hyperglycemia, Hyperlipidemia and Oxidative Stress in Streptozotocin-Induced Diabetic Rats

(2016) Saeed Samarghandian et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Protective effect of crocin on diazinon induced cardiotoxicity in rats in subchronic exposure

(2013) Bibi Marjan Razavi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration

(2013)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report

(2013) Dario Marangoni et al.   Journal of Translational Medicine

Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: A potential anti-arrhythmic agent

(2013) Siyavash Joukar et al.   PHARMACEUTICAL BIOLOGY

Role of saffron and its constituents on cancer chemoprevention

(2013) Zhiyu Zhang et al.   PHARMACEUTICAL BIOLOGY

Safranal Enhances Non-Rapid Eye Movement Sleep in Pentobarbital-Treated Mice

(2012) Zheng Liu et al.   CNS Neuroscience & Therapeutics

Oral administration of crocetin prevents inner retinal damage induced by N-methyl-d-aspartate in mice

(2012) Yuta Ohno et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Longitudinal Follow-Up Study of Saffron Supplementation in Early Age-Related Macular Degeneration: Sustained Benefits to Central Retinal Function

(2012) M. Piccardi et al.   Evidence-based Complementary and Alternative Medicine

Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study

(2012) Ladan Kashani et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Saffron as a Source of Novel Acetylcholinesterase Inhibitors: Molecular Docking and in Vitro Enzymatic Studies

(2012) George D. Geromichalos et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Colchicine poisoning: a case report and review of literature

(2012) YP Raghavendra Babu et al.   MEDICINE SCIENCE AND THE LAW

Effects of the active constituents of Crocus Sativus L., crocins, in an animal model of obsessive–compulsive disorder

(2012) G. Georgiadou et al.   NEUROSCIENCE LETTERS

Effect of Crocin on the Insulin Resistance and Lipid Profile of Streptozotocin-Induced Diabetic Rats

(2012) Saeed Shirali et al.   PHYTOTHERAPY RESEARCH

Safranal, a Saffron Constituent, Attenuates Retinal Degeneration in P23H Rats

(2012) Laura Fernández-Sánchez et al.   PLoS One

Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial

(2012) Amirhossein Modabbernia et al.   PSYCHOPHARMACOLOGY

Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats

(2011) Saurabh Bharti et al.   EUROPEAN JOURNAL OF NUTRITION

Crocin promotes non-rapid eye movement sleep in mice

(2011) Mika Masaki et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Saffron extract and trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices

(2011) F. Berger et al.   NEUROSCIENCE

Psychological and neuroendocrinological effects of odor of saffron (Crocus sativus)

(2011) Hajime Fukui et al.   PHYTOMEDICINE

Immunomodulatory Effects of Saffron: A Randomized Double-Blind Placebo-Controlled Clinical Trial

(2011) S. Kianbakht et al.   PHYTOTHERAPY RESEARCH

Frequency-dependent Electrophysiological Remodeling of the AV Node by Hydroalcohol Extract of Crocus sativus L. (Saffron) During Experimental Atrial Fibrillation: The Role of Endogenous Nitric Oxide

(2011) Vahid Khori et al.   PHYTOTHERAPY RESEARCH

Fibrillation of α-lactalbumin: Effect of crocin and safranal, two natural small molecules from Crocus sativus

(2010) Mohammad-Bagher Ebrahim-Habibi et al.   BIOPOLYMERS

The Effect of Saffron Consumption on Biochemical and Histopathological Heart Indices of Rats with Myocardial Infarction

(2010) Siyavash Joukar et al.   Cardiovascular Toxicology

New Applications and Mechanisms of Action of Saffron and its Important Ingredients

(2010) S. Zahra Bathaie et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity

(2010) Mika Yamauchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment

(2010) M R Safarinejad et al.   INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH

ORIGINAL ARTICLE: Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial

(2010) S. Akhondzadeh et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Evaluation of Crocus sativus L. Stigma Phenolic and Flavonoid Compounds and Its Antioxidant Activity

(2010) Ehsan Karimi et al.   MOLECULES

Satiereal, a Crocus sativus L extract, reduces snacking and increases satiety in a randomized placebo-controlled study of mildly overweight, healthy women

(2010) Bernard Gout et al.   NUTRITION RESEARCH

Effect of crocetin from Gardenia Jasminoides Ellis on sleep: A pilot study

(2010) H. Kuratsune et al.   PHYTOMEDICINE

A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia

(2010) Mohammad Reza Safarinejad et al.   PHYTOTHERAPY RESEARCH

Potential of Crocus sativus (saffron) and its Constituent, Crocin, as Hypolipidemic and Antioxidant in Rats

(2009) Syed Mohammed Basheeruddin Asdaq et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Further Examination of Antiradical Properties ofCrocus sativusStigmas Extract Rich in Crocins

(2009) Stella A. Ordoudi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Effect of an Iranian Herbal Drug on Primary Dysmenorrhea: A Clinical Controlled Trial

(2009) Khodakrami Nahid et al.   JOURNAL OF MIDWIFERY & WOMENS HEALTH

Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: A pilot study

(2009) Ali Shamsa et al.   PHYTOMEDICINE

Anxiolytic and hypnotic effect ofCrocus sativusaqueous extract and its constituents, crocin and safranal, in mice

(2009) Hossein Hosseinzadeh et al.   PHYTOTHERAPY RESEARCH

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

(2009) Shahin Akhondzadeh et al.   PSYCHOPHARMACOLOGY

EFFECT OF CROCETIN ON BLOOD PRESSURE RESTORATION AND SYNTHESIS OF INFLAMMATORY MEDIATORS IN HEART AFTER HEMORRHAGIC SHOCK IN ANESTHETIZED RATS

(2009) Junling Yan et al.   SHOCK

Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial

(2008) M Agha-Hosseini et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

“Fossils” of practical medical knowledge from medieval Cairo

(2008) Efraim Lev et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety

(2008) N. Pitsikas et al.   PHYTOMEDICINE

Quality and Functionality of Saffron: Quality Control, Species Assortment and Affinity of Extract and Isolated Saffron Compounds to NMDA and σ1(Sigma-1) Receptors

(2008) Matthias Lechtenberg et al.   PLANTA MEDICA

The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats

(2007) H. Hosseinzadeh et al.   PHYTOMEDICINE