Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice

Interleukin-6 and oncostatin M are elevated in liver disease in conjunction with candidate hepatocellular carcinoma biomarker GP73

(2017) Hongyan Liang et al.   Cancer Biomarkers

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+monocytes at a site of sterile injury

(2015) Daniela Dal-Secco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatic fibrosis: Concept to treatment

(2015) Christian Trautwein et al.   JOURNAL OF HEPATOLOGY

Semaphorin 3E Secreted by Damaged Hepatocytes Regulates the Sinusoidal Regeneration and Liver Fibrosis during Liver Regeneration

(2014) Tomoki Yagai et al.   AMERICAN JOURNAL OF PATHOLOGY

Roles for Chemokines in Liver Disease

(2014) Fabio Marra et al.   GASTROENTEROLOGY

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Oncostatin M Receptor-  Signaling Limits Monocytic Cell Recruitment in Acute Inflammation

(2014) E. Hams et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis

(2014) A. Mozaffarian et al.   JOURNAL OF IMMUNOLOGY

Oncostatin M overexpression induces matrix deposition, STAT3 activation and SMAD1 Dysregulation in lungs of fibrosis-resistant BALB/c mice

(2014) Steven Wong et al.   LABORATORY INVESTIGATION

Liver cirrhosis

(2014) Emmanuel A Tsochatzis et al.   LANCET

Macrophage plasticity and polarization in liver homeostasis and pathology

(2013) Antonio Sica et al.   HEPATOLOGY

Lack of Oncostatin M Receptor β Leads to Adipose Tissue Inflammation and Insulin Resistance by Switching Macrophage Phenotype

(2013) Tadasuke Komori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

(2013) Stephen J. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

(2012) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Sterile Inflammation in the Liver

(2012) Paul Kubes et al.   GASTROENTEROLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo

(2011) Aline Dumas et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

UPLC methodology for identification and quantitation of naturally fluorescent crosslinks in proteins: A study of bone collagen

(2011) Grażyna E. Sroga et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

p75 Neurotrophin Receptor Is a Marker for Precursors of Stellate Cells and Portal Fibroblasts in Mouse Fetal Liver

(2008) Kaori Suzuki et al.   GASTROENTEROLOGY

Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice

(2008) Rebeca Salguero Palacios et al.   LABORATORY INVESTIGATION

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET