Galectin-9: Diverse roles in hepatic immune homeostasis and inflammation

Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure

(2016) Hugo R. Rosen et al.   Clinical Gastroenterology and Hepatology

Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol

(2016) Hugo R. Rosen et al.   Clinical Gastroenterology and Hepatology

Alcoholic hepatitis: Translational approaches to develop targeted therapies

(2016) Pranoti Mandrekar et al.   HEPATOLOGY

Galectin-9: From cell biology to complex disease dynamics

(2016) Sebastian John et al.   JOURNAL OF BIOSCIENCES

Glycobiology simplified: diverse roles of glycan recognition in inflammation

(2016) Ronald L. Schnaar   JOURNAL OF LEUKOCYTE BIOLOGY

Re-wiring regulatory cell networks in immunity by galectin-glycan interactions

(2015) Ada G. Blidner et al.   FEBS LETTERS

Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis

(2015) Lee J.L. Markwick et al.   GASTROENTEROLOGY

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury

(2015) Yuanxing Liu et al.   JOURNAL OF HEPATOLOGY

HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production

(2015) N. M. K. Harwood et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hepatitis-Associated Liver Cancer: Gaps and Opportunities to Improve Care: Table 1.

(2015) Brian McMahon et al.   JNCI-Journal of the National Cancer Institute

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice

(2015) Hirofumi Hirao et al.   LIVER TRANSPLANTATION

Hepatitis-Associated Liver Cancer: Gaps and Opportunities to Improve Care: Table 1.

(2015) Brian McMahon et al.   JNCI-Journal of the National Cancer Institute

Endothelial LGALS9 splice variant expression in endothelial cell biology and angiogenesis

(2013) Roy Heusschen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Emerging concepts in immunity to hepatitis C virus infection

(2013) Hugo R. Rosen   JOURNAL OF CLINICAL INVESTIGATION

Lessons from look-back in acute liver failure? A single centre experience of 3300 patients

(2013) William Bernal et al.   JOURNAL OF HEPATOLOGY

Tim-3/Galectin-9 Regulate the Homeostasis of Hepatic NKT Cells in a Murine Model of Nonalcoholic Fatty Liver Disease

(2013) Z.-H. Tang et al.   JOURNAL OF IMMUNOLOGY

Galectin-9 Functionally Impairs Natural Killer Cells in Humans and Mice

(2013) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma

(2013) María L Bacigalupo   WORLD JOURNAL OF GASTROENTEROLOGY

Galectin-9 and IL-21 Mediate Cross-regulation between Th17 and Treg Cells during Acute Hepatitis C

(2013) Hassen Kared et al.   PLoS Pathogens

Galectins in acute and chronic inflammation

(2012) Fu-Tong Liu et al.   Annals of the New York Academy of Sciences

Galectin-9 Acts as a Prognostic Factor with Antimetastatic Potential in Hepatocellular Carcinoma

(2012) Zhao-Yang Zhang et al.   Asian Pacific Journal of Cancer Prevention

Pathogenesis of Liver Injury in Acute Liver Failure

(2012) Raymond T. Chung et al.   GASTROENTEROLOGY

The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway

(2012) Rodrigo Liberal et al.   HEPATOLOGY

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY

Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4+CD25low/int Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

(2012) Kun Lv et al.   PLoS One

Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection

(2012) Gaia Nebbia et al.   PLoS One

A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses

(2012) Clément Barjon et al.   Infectious Agents and Cancer

Therapeutic potential of Galectin-9 in human disease

(2011) Valerie R. Wiersma et al.   MEDICINAL RESEARCH REVIEWS

T-Cell Immunoglobulin Mucin-3 Determines Severity of Liver Ischemia/Reperfusion Injury in Mice in a TLR4-Dependent Manner

(2010) Yoichiro Uchida et al.   GASTROENTEROLOGY

A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis

(2010) Silvia Ferri et al.   HEPATOLOGY

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity

(2010) Yurong Li et al.   MOLECULAR IMMUNOLOGY

A Crucial Role for Kupffer Cell-Derived Galectin-9 in Regulation of T Cell Immunity in Hepatitis C Infection

(2010) John A. Mengshol et al.   PLoS One

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells

(2008) Xiong Ma et al.   JOURNAL OF HEPATOLOGY

Reciprocal Activation Between CD4+ T Cells and Kupffer Cells During Hepatic Ischemia-Reperfusion

(2008) Marc Hanschen et al.   TRANSPLANTATION

Structural Analysis of the Human Galectin-9 N-terminal Carbohydrate Recognition Domain Reveals Unexpected Properties that Differ from the Mouse Orthologue

(2007) Masamichi Nagae et al.   JOURNAL OF MOLECULAR BIOLOGY