Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics

The genetic burden of inflammatory bowel diseases: implications for the clinic?

(2016) Tommaso Gabbani et al.   Expert Review of Gastroenterology & Hepatology

How will new and future therapies change our treatment of IBD?

(2015) Sebastian Zundler et al.   Expert Review of Clinical Immunology

Immune deficiency vs. immune excess in inflammatory bowel diseases-STAT3 as a rheo-STAT of intestinal homeostasis

(2015) Moritz Leppkes et al.   JOURNAL OF LEUKOCYTE BIOLOGY

T-Cell Trafficking and Anti-Adhesion Strategies in Inflammatory Bowel Disease: Current and Future Prospects

(2014) Mahmoud H. Mosli et al.   DRUGS

Immunology of Inflammatory Bowel Disease and Molecular Targets for Biologics

(2014) Maneesh Dave et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

(2014) Séverine Vermeire et al.   LANCET

Molecular pathways controlling barrier function in IBD

(2014) Raja Atreya et al.   Nature Reviews Gastroenterology & Hepatology

Regulation and pathophysiological role of epithelial turnover in the gut

(2014) Claudia Günther et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Inflammatory Bowel Disease: Mechanisms, Redox Considerations, and Therapeutic Targets

(2013) Fiorella Biasi et al.   ANTIOXIDANTS & REDOX SIGNALING

Advances in therapeutic interventions targeting the vascular and lymphatic endothelium in inflammatory bowel disease

(2013) Silvia D’Alessio et al.   CURRENT OPINION IN GASTROENTEROLOGY

Targeting Interleukins for the Treatment of Inflammatory Bowel Disease—What Lies Beyond Anti-TNF Therapy?

(2013) Mairi H. McLean et al.   INFLAMMATORY BOWEL DISEASES

Pre- and Posttherapy Assessment of Intestinal Soluble Mediators in IBD: Where We Stand and Future Perspectives

(2013) F. Scaldaferri et al.   MEDIATORS OF INFLAMMATION

New targets for mucosal healing and therapy in inflammatory bowel diseases

(2013) M F Neurath   Mucosal Immunology

Emerging regulation and functions of autophagy

(2013) Patricia Boya et al.   NATURE CELL BIOLOGY

Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases

(2013) Jing Li et al.   PHARMACOLOGY & THERAPEUTICS

Complex Roles of Caspases in the Pathogenesis of Inflammatory Bowel Disease

(2012) Christoph Becker et al.   GASTROENTEROLOGY

Hospitalisations and surgery in Crohn's disease

(2012) Charles N Bernstein et al.   GUT

Efficacy of adalimumab in patients with crohn's disease and failure to infliximab therapy: a clinical series

(2012) Patricia Cordero-Ruiz et al.   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Antibodies Against Tumor Necrosis Factor (TNF) Induce T-Cell Apoptosis in Patients With Inflammatory Bowel Diseases via TNF Receptor 2 and Intestinal CD14+ Macrophages

(2011) Raja Atreya et al.   GASTROENTEROLOGY

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

The JAK2 variant rs10758669 in Crohn’s disease: altering the intestinal barrier as one mechanism of action

(2011) Matthias Prager et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Cellular and Molecular Mechanisms in the Two Major Forms of Inflammatory Bowel Disease

(2011) Laszlo Bene et al.   PATHOLOGY & ONCOLOGY RESEARCH

Chemokines as Novel Therapeutic Targets for Inflammatory Bowel Disease

(2009) Miyuki Nishimura et al.   Annals of the New York Academy of Sciences

IL-1β-511 and IL-1RN*2 polymorphisms in inflammatory bowel disease: An Italian population study and meta-analysis of European studies

(2009) Vito D. Corleto et al.   DIGESTIVE AND LIVER DISEASE

Interleukin-10 in Inflammatory Bowel Disease

(2009) Brian Kelsall   NEW ENGLAND JOURNAL OF MEDICINE

CD4 T-cell differentiation and inflammatory bowel disease

(2009) Lauren A. Zenewicz et al.   TRENDS IN MOLECULAR MEDICINE

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA