The JAK2 variant rs10758669 in Crohn’s disease: altering the intestinal barrier as one mechanism of action

IL-1β-Induced Increase in Intestinal Epithelial Tight Junction Permeability Is Mediated by MEKK-1 Activation of Canonical NF-κB Pathway

(2010) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

(2010) T. T. MACDONALD et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Innate antimicrobial immunity in inflammatory bowel diseases

(2010) Julia Beisner et al.   Expert Review of Clinical Immunology

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

(2010) Natalie J. Prescott et al.   HUMAN MOLECULAR GENETICS

Importance of disrupted intestinal barrier in inflammatory bowel diseases

(2010) Saʼad Y. Salim et al.   INFLAMMATORY BOWEL DISEASES

Paneth's disease

(2010) Jan Wehkamp et al.   Journal of Crohns & Colitis

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management

(2010) A. Dignass et al.   Journal of Crohns & Colitis

Genetic factors in chronic inflammation: Single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn's disease in a New Zealand population

(2010) Lynnette R. Ferguson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

(2010) John D Reveille et al.   NATURE GENETICS

Confirmation of Multiple Crohn's Disease Susceptibility Loci in a Large Dutch–Belgian Cohort

(2009) Rinse K Weersma et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn’s Disease in the Japanese Population

(2009) Kayoko Sato et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Polymorphism of the IRGM Gene Might Predispose to Fistulizing Behavior in Crohn's Disease

(2008) A Latiano et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Investigation of Crohn's Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship

(2008) Carl A. Anderson et al.   GASTROENTEROLOGY

Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients

(2008) K Yamazaki et al.   GUT

Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis

(2008) R. J Xavier et al.   GUT

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

(2008) Andre Franke et al.   NATURE GENETICS

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

(2008) Steven A McCarroll et al.   NATURE GENETICS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics