Genetic evidence for common pathways in human age-related diseases

Starting Primary Prevention Earlier With Statins

(2014) Jennifer G. Robinson   AMERICAN JOURNAL OF CARDIOLOGY

Genome-wide association studies and the clinic: a focus on breast cancer

(2014) Amélie Véron et al.   Biomarkers in Medicine

Genetics of aging, progeria and lamin disorders

(2014) Shrestha Ghosh et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Genetic markers for diagnosis and pathogenesis of Alzheimer's disease

(2014) Dong Hee Kim et al.   GENE

Genome-Wide Family-Based Linkage Analysis of Exome Chip Variants and Cardiometabolic Risk

(2014) Jacklyn N. Hellwege et al.   GENETIC EPIDEMIOLOGY

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans

(2014) Jaclyn Ellis et al.   HUMAN GENETICS

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

(2014) Joris Deelen et al.   HUMAN MOLECULAR GENETICS

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

(2014) Ursula M. Schick et al.   HUMAN MOLECULAR GENETICS

Epigenetics of Aging and Aging-related Disease

(2014) A. Brunet et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Medical research: Treat ageing

(2014) Luigi Fontana et al.   NATURE

Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

(2014) Diana Jurk et al.   Nature Communications

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease

(2014) Adam C. Naj et al.   JAMA Neurology

Molecular mechanisms underlying genotype-dependent responses to dietary restriction

(2013) Jennifer Schleit et al.   AGING CELL

Genome Instability and Aging

(2013) Jan Vijg et al.   Annual Review of Physiology

Fisher's method of combining dependent statistics using generalizations of the gamma distribution with applications to genetic pleiotropic associations

(2013) Q. Li et al.   BIOSTATISTICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Genome-wide Association Studies in Alzheimer’s Disease: A Review

(2013) Giuseppe Tosto et al.   Current Neurology and Neuroscience Reports

A new pleiotropic effect of statins in elderly: modulation of telomerase activity

(2013) Virginia Boccardi et al.   FASEB JOURNAL

APOE Modulates the Correlation Between Triglycerides, Cholesterol, and CHD Through Pleiotropy, and Gene-by-Gene Interactions

(2013) T. J. Maxwell et al.   GENETICS

Lessons from postgenome-wide association studies: functional analysis of cancer predisposition loci

(2013) A. N. A. Monteiro et al.   JOURNAL OF INTERNAL MEDICINE

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

The p66Shc gene paves the way for healthspan: Evolutionary and mechanistic perspectives

(2013) Alessandra Berry et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

The prostate cancer genome: Perspectives and potential

(2013) Christopher E. Barbieri et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Healthy aging: what can we learn from Caenorhabditis elegans?

(2013) A. Torgovnick et al.   ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE

Review: a meta-analysis of GWAS and age-associated diseases

(2012) William R. Jeck et al.   AGING CELL

Low-Density Lipoprotein Cholesterol, Apolipoprotein B, and Risk of Coronary Heart Disease: From Familial Hyperlipidemia to Genomics

(2012) C. C. Imes et al.   Biological Research for Nursing

Mutations of the Apolipoprotein A5 Gene with Inherited Hypertriglyceridaemia: Review of the Current Literature

(2012) B. I. Melegh et al.   CURRENT MEDICINAL CHEMISTRY

Genetics of subcortical vascular dementia

(2012) Helena Schmidt et al.   EXPERIMENTAL GERONTOLOGY

Population genetics of chronic kidney disease: The evolving story of APOL1

(2012) Walter G. Wasser et al.   JOURNAL OF NEPHROLOGY

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

(2012) G Davies et al.   MOLECULAR PSYCHIATRY

Loss of Prohibitin Membrane Scaffolds Impairs Mitochondrial Architecture and Leads to Tau Hyperphosphorylation and Neurodegeneration

(2012) Carsten Merkwirth et al.   PLoS Genetics

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

(2011) Joris Deelen et al.   AGING CELL

Stochastic modulations of the pace and patterns of ageing: Impacts on quasi-stochastic distributions of multiple geriatric pathologies

(2011) George M. Martin   MECHANISMS OF AGEING AND DEVELOPMENT

A genome-wide association study of aging

(2011) Stefan Walter et al.   NEUROBIOLOGY OF AGING

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

GOSemSim: an R package for measuring semantic similarity among GO terms and gene products

(2010) G. Yu et al.   BIOINFORMATICS

A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

(2010) Anne B. Newman et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

(2010) M. Beekman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

SCAN: SNP and copy number annotation

(2009) Eric R. Gamazon et al.   BIOINFORMATICS

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Effects of the Mediterranean diet on longevity and age-related morbid conditions

(2009) Faustino R. Pérez-López et al.   MATURITAS