Intramembranous processing by γ-secretase regulates reverse signaling of ephrin-B2 in migration of microglia

The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases

(2015) Jochen Walter   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia

(2015) Alexander Aslanidis et al.   Journal of Neuroinflammation

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

Understanding intramembrane proteolysis: from protein dynamics to reaction kinetics

(2015) D. Langosch et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ephrin signalling in the developing nervous system

(2014) Rüdiger Klein et al.   CURRENT OPINION IN NEUROBIOLOGY

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

A dual role of EphB1/ephrin-B3 reverse signaling on migrating striatal and cortical neurons originating in the preoptic area: should I stay or go away?

(2014) Judith Rudolph et al.   Frontiers in Cellular Neuroscience

The role of proteases in regulating Eph/ephrin signaling

(2014) Lakmali Atapattu et al.   Cell Adhesion & Migration

Nontranscriptional Role of Hif-1α in Activation of γ-Secretase and Notch Signaling in Breast Cancer

(2014) Jennifer C. Villa et al.   Cell Reports

Unique transcriptome signature of mouse microglia

(2013) Clara Beutner et al.   GLIA

Podosomes in migrating microglia: components and matrix degradation

(2012) Catherine Vincent et al.   Journal of Neuroinflammation

Coordinated Eph-ephrin signaling guides migration and axon targeting in the avian auditory system

(2012) Michelle R Allen-Sharpley et al.   Neural Development

Presenilin1/γ-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein

(2011) Anastasios Georgakopoulos et al.   FASEB JOURNAL

Critical Role of Astroglial Apolipoprotein E and Liver X Receptor-  Expression for Microglial A  Phagocytosis

(2011) D. Terwel et al.   JOURNAL OF NEUROSCIENCE

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration

(2011) Aycan Sentürk et al.   NATURE

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Novel Research Horizons for Presenilins and γ-Secretases in Cell Biology and Disease

(2010) Bart De Strooper et al.   Annual Review of Cell and Developmental Biology

ADAM13 Induces Cranial Neural Crest by Cleaving Class B Ephrins and Regulating Wnt Signaling

(2010) Shuo Wei et al.   DEVELOPMENTAL CELL

Ephrin-B2 elicits differential growth cone collapse and axon retraction in retinal ganglion cells from distinct retinal regions

(2010) Timothy J. Petros et al.   Developmental Neurobiology

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

Generation of microglial cells from mouse embryonic stem cells

(2010) Clara Beutner et al.   Nature Protocols

Microglial precursors derived from mouse embryonic stem cells

(2009) Isabella Napoli et al.   GLIA

Presenilin 1 Affects Focal Adhesion Site Formation and Cell Force Generation via c-Src Transcriptional and Posttranslational Regulation

(2009) Dieter Waschbüsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptide EphB2/CTF2 Generated by the γ-Secretase Processing of EphB2 Receptor Promotes Tyrosine Phosphorylation and Cell Surface Localization ofN-Methyl-d-aspartate Receptors

(2009) Jindong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic activity prompts γ-secretase–mediated cleavage of EphA4 and dendritic spine formation

(2009) Eiji Inoue et al.   JOURNAL OF CELL BIOLOGY

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Eph-Ephrin Bidirectional Signaling in Physiology and Disease

(2008) Elena B. Pasquale   CELL