Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia

Retinal microglia: Just bystander or target for therapy?

(2015) Marcus Karlstetter et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration

(2014) Marcus Karlstetter et al.   HUMAN MOLECULAR GENETICS

IFN- -Induced TNF-  Expression Is Regulated by Interferon Regulatory Factors 1 and 8 in Mouse Macrophages

(2014) V. Vila-del Sol et al.   JOURNAL OF IMMUNOLOGY

Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis

(2014) Marcus Karlstetter et al.   Journal of Neuroinflammation

Secretory Leukocyte Protease Inhibitor (SLPI)

(2014) Sari S. Hannila   NEUROSCIENTIST

A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation

(2013) O. Klimenkova et al.   BLOOD

Unique transcriptome signature of mouse microglia

(2013) Clara Beutner et al.   GLIA

Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1G93A mouse model

(2013) Eitan Lilo et al.   HUMAN MOLECULAR GENETICS

Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal

(2013) Hideo Kohno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human cytomegalovirus directly modulates expression of chemokine CCL2 (MCP-1) during viral replication

(2013) S. T. Hamilton et al.   JOURNAL OF GENERAL VIROLOGY

Secretory Leukocyte Protease Inhibitor Reverses Inhibition by CNS Myelin, Promotes Regeneration in the Optic Nerve, and Suppresses Expression of the Transforming Growth Factor-  Signaling Protein Smad2

(2013) S. S. Hannila et al.   JOURNAL OF NEUROSCIENCE

Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis

(2013) Amanda Sierra et al.   Frontiers in Cellular Neuroscience

SLPI and elafin: multifunctional antiproteases of the WFDC family

(2012) Aaron Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling

(2012) X. Jin et al.   BRAIN

An improved method for enhanced production and biological activity of human secretory leukocyte protease inhibitor (SLPI) in Pichia pastoris

(2010) Zhiguo Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury

(2010) Nader Ghasemlou et al.   BRAIN

The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response

(2010) M. Karlstetter et al.   JOURNAL OF IMMUNOLOGY

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

(2010) Konstantin Dirscherl et al.   Journal of Neuroinflammation

Generation of microglial cells from mouse embryonic stem cells

(2010) Clara Beutner et al.   Nature Protocols

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis

(2010) Devipriya SUBRAMANIYAM et al.   RESPIROLOGY

Microglial precursors derived from mouse embryonic stem cells

(2009) Isabella Napoli et al.   GLIA

Ubiquitylation in innate and adaptive immunity

(2009) Vijay G. Bhoj et al.   NATURE

Expression and characterization of recombinant human secretory leukocyte protease inhibitor (SLPI) protein from Pichia pastoris

(2009) Zhiguo Li et al.   PROTEIN EXPRESSION AND PURIFICATION

Chondroitin sulfate disaccharide stimulates microglia to adopt a novel regulatory phenotype

(2008) Stefanie Ebert et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils

(2008) Lars C. Jacobsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis

(2008) Andre M Mueller et al.   Journal of Neuroinflammation

Novel innate immune functions of the whey acidic protein family

(2008) Colin D Bingle et al.   TRENDS IN IMMUNOLOGY