Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo
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Title
Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo
Authors
Keywords
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Journal
ONCOGENE
Volume 30, Issue 32, Pages 3522-3536
Publisher
Springer Nature
Online
2011-03-21
DOI
10.1038/onc.2011.70
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Related references
Note: Only part of the references are listed.- The CCN3 gene coding for an extracellular adhesion-related protein is transcriptionally activated by the p53 tumor suppressor
- (2011) Levin Böhlig et al. CELL CYCLE
- The Origin and Pathogenesis of Epithelial Ovarian Cancer: A Proposed Unifying Theory
- (2010) Robert J. Kurman et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells
- (2010) Nathan J Bowen et al. BMC Medical Genomics
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- (2010) B. M. Costa et al. CANCER RESEARCH
- Molecular Profiling Uncovers a p53-Associated Role for MicroRNA-31 in Inhibiting the Proliferation of Serous Ovarian Carcinomas and Other Cancers
- (2010) C. J. Creighton et al. CANCER RESEARCH
- Frequent Downregulation of miR-34 Family in Human Ovarian Cancers
- (2010) D. C. Corney et al. CLINICAL CANCER RESEARCH
- p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal
- (2010) Z. Zhao et al. GENES & DEVELOPMENT
- The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment
- (2010) E. Despierre et al. GYNECOLOGIC ONCOLOGY
- High-grade fimbrial-ovarian carcinomas are unified by altered p53, PTEN and PAX2 expression
- (2010) Michael H Roh et al. MODERN PATHOLOGY
- The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
- (2010) Y. Wang et al. SCIENCE
- Oncogenic Kras Requires Simultaneous PI3K Signaling to Induce ERK Activation and Transform Thyroid Epithelial Cells In vivo
- (2009) K. A. Miller et al. CANCER RESEARCH
- Cell Type-Specific Targeted Mutations of Kras and Pten Document Proliferation Arrest in Granulosa Cells versus Oncogenic Insult to Ovarian Surface Epithelial Cells
- (2009) H.-Y. Fan et al. CANCER RESEARCH
- PI3K Pathway Activation Mediates Resistance to MEK Inhibitors in KRAS Mutant Cancers
- (2009) S. Wee et al. CANCER RESEARCH
- A Role for BRCA1 in Uterine Leiomyosarcoma
- (2009) D. Xing et al. CANCER RESEARCH
- Rapamycin Prevents Early Onset of Tumorigenesis in an Oral-Specific K-ras and p53 Two-Hit Carcinogenesis Model
- (2009) A. R. Raimondi et al. CANCER RESEARCH
- miR-29 suppression of osteonectin in osteoblasts: Regulation during differentiation and by canonical Wnt signaling
- (2009) Kristina Kapinas et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Müllerian HOXA10 gene promotes growth of ovarian surface epithelial cells by stimulating epithelial–stromal interactions
- (2009) Song Yi Ko et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Expression of the acute phase protein haptoglobin in human lung cancer and tumor-free lung tissues
- (2009) Mahdi Abdullah et al. PATHOLOGY RESEARCH AND PRACTICE
- Expression of Activated PIK3CA in Ovarian Surface Epithelium Results in Hyperplasia but Not Tumor Formation
- (2009) Shun Liang et al. PLoS One
- Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol
- (2009) Franziska B. Mullauer et al. PLoS One
- Repertoire of microRNAs in Epithelial Ovarian Cancer as Determined by Next Generation Sequencing of Small RNA cDNA Libraries
- (2009) Stacia K. Wyman et al. PLoS One
- Conditional Inactivation of Brca1, p53 and Rb in Mouse Ovaries Results in the Development of Leiomyosarcomas
- (2009) Katherine V. Clark-Knowles et al. PLoS One
- MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility
- (2009) H.-Y. Fan et al. SCIENCE
- Ovarian Cancer Pathogenesis: A Model in Evolution
- (2009) Alison M. Karst et al. Journal of Oncology
- Ovarian Cancer
- (2008) Kathleen R. Cho et al. Annual Review of Pathology-Mechanisms of Disease
- MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
- (2008) H. Yang et al. CANCER RESEARCH
- Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression
- (2008) Marie-Noëlle Laguë et al. CARCINOGENESIS
- MicroRNA Expression Profiles in Serous Ovarian Carcinoma
- (2008) E. J. Nam et al. CLINICAL CANCER RESEARCH
- Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation
- (2008) H.-Y. Fan et al. DEVELOPMENT
- The origin of ovarian carcinomas: A developmental view
- (2008) Nelly Auersperg et al. GYNECOLOGIC ONCOLOGY
- Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer
- (2008) A. Astanehe et al. JOURNAL OF CELL SCIENCE
- miR-21: a small multi-faceted RNA
- (2008) Anna M. Krichevsky et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The cell of origin of ovarian epithelial tumours
- (2008) Louis Dubeau LANCET ONCOLOGY
- Large-scale genomic analysis of ovarian carcinomas
- (2008) Kylie L. Gorringe et al. Molecular Oncology
- A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
- (2008) Agnieszka Rybak et al. NATURE CELL BIOLOGY
- Small non-coding RNAs in animal development
- (2008) Giovanni Stefani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- miR-29 miRNAs activate p53 by targeting p85α and CDC42
- (2008) Seong-Yeon Park et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The let-7 family of microRNAs
- (2008) Sarah Roush et al. TRENDS IN CELL BIOLOGY
- Gene-expression profiling in epithelial ovarian cancer
- (2008) Panagiotis A Konstantinopoulos et al. Nature clinical practice. Oncology
- Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies
- (2008) Martin Köbel et al. PLOS MEDICINE
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