Article
Plant Sciences
Peerapong Jeeno, Sukit Tongban, Pichamon Yana, Anurak Wongta, Kunrunya Sutan, Sumed Yadoung, Surat Hongsibsong
Summary: Phytochemicals extracted from Smilax glabra and Smilax corbularia were identified and found to have antioxidant and antimicrobial activities. These plants can be potential sources of antioxidants and herbal medicines for treating Gram-positive bacterial infections.
Article
Food Science & Technology
Daniela Nova-Baza, Lia Olivares-Caro, Luis Bustamante, Andy J. Perez, Carola Vergara, Jorge Fuentealba, Claudia Mardones
Summary: A comprehensive study on bioactive compounds in the leaves of main Berberis species growing in Chile was conducted. 117 compounds including phenolic acids, alkaloids, flavonols, and other compounds were identified. Hydroxycinnamic acid derivatives and quercetin derivatives were found to be the main compounds. Fatty acid profile and antioxidant capacity also varied among different species. These findings provide insights for novel approaches in utilizing these leaves as natural food or ingredient.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Agriculture, Multidisciplinary
Takehiro Watanabe, Kohki Fujikawa, Soichiro Urai, Kazunari Iwaki, Tadayoshi Hirai, Katsuro Miyagawa, Hiroshi Uratani, Tohru Yamagaki, Koji Nagao, Yoshiaki Yokoo, Keiko Shimamoto
Summary: In this study, five unreported steviol glycosides containing rhamnose or xylose were extracted from developing stevia leaves, and their sweetness was evaluated. The structures of these glycosides were confirmed and their sensory evaluation was conducted. One xylose-containing glycoside, rebaudioside FX1, showed a well-balanced sweetness and is a promising candidate for natural sweeteners in the food industry.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Environmental Sciences
Christina Christia, Katyeny Manuela da Silva, Giulia Poma, Adrian Covaci
Summary: In this study, a suspect screening workflow combined with a semi-quantification method was used to investigate the metabolites of DiPGDB and TBTM in human urine samples collected during winter and summer. Several metabolites were identified, and the DiPGDB-M310, DiPGDB-M194, and TBTM-M498 were suggested as potential biomarkers for assessing human exposure to DiPGDB and TBTM. The semi-quantification method is valuable for studies that lack analytical standards.
Article
Chemistry, Analytical
Kiwao Kadokami, Takashi Miyawaki, Sokichi Takagi, Katsumi Iwabuchi, Hironori Towatari, Tomohiro Yoshino, Masahiro Yagi, Yuji Aita, Tomoko Ito, Shusuke Takemine, Daisuke Nakajima, Xuehua Li
Summary: This study has developed an automated identification and quantification system for toxic chemicals, which is highly efficient, low-cost, labor-saving, and environmentally friendly. It uses a novel acquisition method to obtain accurate mass spectrometry data with minimal interference from co-eluted peaks. Collaborative tests demonstrate the accuracy and reliability of the system, meeting the standards for analytical method validity.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Debasish Swain, Narendra Kumar Nagendla, Mohana Krishna Reddy Mudiam
Summary: Lenvatinib mesylate is a new generation anti-cancer medication used for differentiated thyroid cancers that have not responded to conventional treatment. Forced degradation studies provide crucial information about the stability of the drug under different conditions, and play a significant role in drug development.
MICROCHEMICAL JOURNAL
(2023)
Article
Food Science & Technology
Kewen Wang, Lei Xu, Xue Wang, Ailiang Chen, Zhenzhen Xu
Summary: The study compared DART-QTOF and LC-ESI-QTOF in discriminating beef from different origins based on lipidomics, showing DART-QTOF to be more suitable for smaller compounds analysis and LC-ESI-QTOF performing better in SVM models.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Nguyen Hai Doan, Hanh Thi Duong, Ha Thu Trinh, Yoshinari Tanaka, Kiwao Kadokami
Summary: Air pollution is a serious issue in Vietnam's big cities, with limited data on organic micro-pollutants in atmospheric particulate matters, especially in regards to pesticides. A study surveyed 107 insecticides in APMs and detected 19 insecticides, with many being reported for the first time.
Article
Engineering, Environmental
Ryo Omagari, Mayuko Yagishita, Fujio Shiraishi, Shoji F. Nakayama, Masanori Terasaki, Tetsuya Tanigawa, Ichiro Yamauchi, Takuya Kubo, Daisuke Nakajima
Summary: 3,3',5-Triiodothyroacetic acid (TRIAC) is a major contributor to the activity of thyroid hormone receptor agonists in environmental water. It may cause disruption of the thyroid system in living aquatic organisms. The study found that T3 and T4 in influents of sewage treatment plants may be converted into TRIAC during treatment processes.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Plant Sciences
Nathalie N. Kamou, Natasa P. Kalogiouri, Panagiota Tryfon, Anastasia Papadopoulou, Katerina Karamanoli, Catherine Dendrinou-Samara, Urania Menkissoglu-Spiroudi
Summary: This study investigated the efficacy of the bioactive substance geraniol against B. cinerea in vitro and in planta. The metabolic profile of cucumber plants inoculated with the pathogen and/or treated with geraniol was analyzed using a novel LC-QTOF-MS method. Furthermore, geraniol-loaded nanoemulsions were synthesized and tested as an integrated application mode. The results showed that geraniol and nanoemulsions effectively inhibited B. cinerea growth.
Article
Biochemistry & Molecular Biology
Barbara Chilczuk, Beata Marciniak, Renata Kontek, Malgorzata Materska
Summary: Ethanol extracts of sweet and hot peppers were separated into fractions based on their lipophilicity, and their chemical composition, anti-radical activity, and cytotoxicity were analyzed. The study found that the chemical composition did not always correlate with biological activity, and unique compounds in the extracts could modulate their effects, which must be confirmed experimentally.
Article
Plant Sciences
Sweeta Akbari, Nour Hamid Abdurahman, Rosli Mohd Yunus, Ali Hassan Abdulrahman Alsaggaf, Noormazlinah Ahmed
Summary: Aloe vera, a well-known medicinal plant in the Liliaceae family, was extracted via microwave-assisted extraction (MAE) to determine yield, total phenolic content (TPC), and total saponin content (TSC). LC-QTOF-MS analysis identified 32 phenolics and 29 saponin compounds in the extract, including steroid and triterpenoid saponins. The optimal MAE conditions resulted in a yield of 36.17%, with TPC and TSC levels of 73.05 mg GAE/g d.w and 65.89 mg OAE/g d.w, respectively.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Food Science & Technology
Aileen Pua, Wei Xian Desmond Choo, Rui Min Vivian Goh, Shao Quan Liu, Maurin Cornuz, Kim-Huey Ee, Jingcan Sun, Benjamin Lassabliere, Bin Yu
Summary: This study systematically characterized the volatile and nonvolatile compositions of five cascaras, identified key odourants and quantified non-volatile compounds to understand their organoleptic and antioxidant properties. Differentiation of the cascaras through principal component analysis may facilitate further research on their application.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Ji-Min Lv, Mostafa Gouda, Alaa El-Din Bekhit, Ya-Ke He, Xing-Qian Ye, Jian-Chu Chen
Summary: This study investigated the potential use of kiwifruit leaves waste as a source of proanthocyanidins (PAs). The results showed that kiwifruit leaves PAs exhibited higher phenolic content and antioxidant activity than other parts of the kiwifruit. Moreover, they showed dose-dependent anti-proliferation activity against HepG2 cells. This study highlights the importance of utilizing agro-wastes for valuable product production.
Article
Engineering, Chemical
Zifan Liu, Linghong Shi, Yunyang Qi, Colin J. Barrow, Frank R. Dunshea, Hafiz A. R. Suleria
Summary: Kiwifruit peels have the highest content of phenolic compounds and antioxidant capacity compared to the pulp and cores, making them a potential source of antioxidants. This study provides valuable information on the waste parts of kiwifruit for the industry, guiding its utilization in the food and pharmacological aspects.
Article
Chemistry, Analytical
A. Fernandez-Vega, E. Chicano-Galvez, B. M. Prentice, D. Anderson, F. Priego-Capote, M. A. Lopez-Bascon, M. Calderon-Santiago, M. S. Avendano, R. Guzman-Ruiz, M. Tena-Sempere, J. A. Fernandez, R. M. Caprioli, M. M. Malagon
Article
Chemistry, Applied
H. Miho, J. Moral, D. Barranco, C. A. Ledesma-Escobar, F. Priego-Capote, C. M. Diez
Summary: In this study, 44 olive tree cultivars were evaluated for the phenolic profile of virgin olive oil (VOO), revealing significant variations in total phenol concentration among cultivars with the 'cultivar' factor contributing the most to the variance. The presence of three groups of cultivars with distinct phenolic profiles highlights the importance of considering phenolic composition in olive breeding programs.
Article
Chemistry, Analytical
L. S. Castillo-Peinado, M. Calderon-Santiago, F. Priego-Capote
Summary: The determination of vitamin D levels in human biological specimens is crucial due to its association with various biological disorders. Lyophilization of serum and plasma for sample storage prior to analysis does not affect sensitivity, precision, or accuracy, and can increase stability of target analytes.
Article
Agriculture, Multidisciplinary
Sonia Tome-Rodriguez, Carlos A. Ledesma-Escobar, Jose M. Penco-Valenzuela, Feliciano Priego-Capote
Summary: This study developed a method for qualitative and semi-quantitative determination of volatile components in thermally stressed virgin olive oils using HS-GC-MS. The volatile components were found to be closely correlated with the concentration of the main unsaturated fatty acids, explaining their impact on organoleptic properties.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Chemistry, Analytical
D. Luque-Cordoba, F. Priego-Capote
Summary: Steroidogenesis is a crucial process in maintaining physiological levels of steroids in the body, and its deficiency can lead to various pathologies. A research has developed a high-throughput and fully automated method for quantifying multiple steroids in human serum, achieving high sensitivity and selectivity. This method was tested on human serum samples and showed satisfactory results in line with physiological ranges reported in literature.
Article
Chemistry, Analytical
Laura de Los Santos Castillo-Peinado, Monica Calderon-Santiago, Aura Dulcinea Herrera-Martinez, Soraya Leon-Idougourram, Maria Angeles Galvez-Moreno, Rafael Luis Sanchez-Cano, Roger Bouillon, Jose Manuel Quesada-Gomez, Feliciano Priego-Capote
Summary: This study developed a method for measuring vitamin D-3 metabolism by analyzing multiple metabolites in human plasma, providing a comprehensive view of vitamin D-3 metabolism. The method was used to investigate metabolic correlations and differences between obese patients and healthy volunteers.
Article
Chemistry, Analytical
Laura de los Santos Castillo-Peinado, Monica Calderon-Santiago, Rafael Luis Sanchez-Cano, Jose Manuel Quesada-Gomez, Roger Bouillon, Feliciano Priego-Capote
Summary: Experts define vitamin D deficiency levels by the determination of a circulating 25-hydroxyvitamin D-3-calcifediol prohormone. Despite individuals not being affected by any disorder, a large part of the population is characterized by deficient vitamin D levels. This study proposes a quantitative method for the combined determination of phase I and phase II vitamin D-3 metabolites in human serum using tandem mass spectrometry detection.
Article
Chemistry, Analytical
Enrique C. Cabanas-Garrido, Carlos A. Ledesma-Escobar, Feliciano Priego-Capote
Summary: In the SARS-COV-2 pandemic, the use of surgical masks has been found to effectively reduce the transmission rate of the virus. Researchers have developed a method to analyze volatile organic compounds (VOCs) retained in surgical masks and identified 63 compounds associated with various chemical families. The study suggests that surgical masks can serve as a simple and inexpensive sampling system for VOC analysis.
Article
Biochemistry & Molecular Biology
Alejandro Hinojosa-Moscoso, Anna Motger-Alberti, Elena De la Calle-Vargas, Marian Marti-Navas, Carles Biarnes, Maria Arnoriaga-Rodriguez, Gerard Blasco, Josep Puig, Diego Luque-Cordoba, Feliciano Priego-Capote, Jose Maria Moreno-Navarrete, Jose Manuel Fernandez-Real
Summary: Excess iron is associated with dysfunction in adipose tissue and insulin resistance. In this study, it was found that markers of iron status were linked to changes in abdominal adipose tissue over one year. These associations were mainly observed in women and non-obese subjects, and were independent of insulin sensitivity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Analytical
Carlos Augusto Ledesma-Escobar, Feliciano Priego-Capote, Monica Calderon-Santiago
Summary: MetaboMSDIA is a complete processing method for data-independent acquisition (DIA) files that extracts multiplexed MS2 spectra and identifies metabolites from open libraries. It improves the acquisition coverage and spectral quality in untargeted metabolomics, which are crucial for the tentative annotation of metabolites.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Applied
S. Tome-Rodriguez, F. Barba-Palomeque, C. A. Ledesma-Escobar, H. Miho, C. M. Diez, F. Priego-Capote
Summary: One of the nutritional benefits of olive oil is its high content of monounsaturated fatty acids (MUFAs). We studied the fatty acids composition of virgin olive oil samples obtained from different cultivars over multiple crop seasons. The cultivars were categorized into two groups based on their MUFAs content. We also found that the fatty acids profile can be influenced by the climate conditions, with reduced precipitation leading to a decrease in MUFAs and an increase in SFAs/PUFAs concentrations.
Article
Clinical Neurology
Laura S. Castillo-Peinado, Monica Calderon-Santiago, Bernabe Jurado-Gamez, Feliciano Priego-Capote
Summary: This study aimed to evaluate metabolic changes in sweat to aid in the diagnosis and assessment of cardiovascular consequences in obstructive sleep apnea (OSA). Permanent significant alterations in sweat metabolites were reported, and lactose, succinate, urea, and oxoproline were found to have significantly different effects on the severity of OSA.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Food Science & Technology
Ana Castillo-Luna, Hristofor Miho, Carlos A. Ledesma-Escobar, Feliciano Priego-Capote
Summary: Olive tree vegetal materials are a rich source of bioactive compounds, but their high moisture content hinders their preservation and extraction. Thus, a drying step is crucial for efficient extraction.
Article
Endocrinology & Metabolism
D. Luque-Cordoba, M. Calderon-Santiago, F. Priego-Capote
Summary: This study presents a strategy for identification and quantitative determination of acylcarnitines, metabolites involved in fatty acid beta-oxidation and organic acid metabolism, for evaluating metabolic disorders. The method combines data-independent acquisition and data-dependent acquisition techniques, achieving high accuracy and precision. The study also reveals significant differences in the acylcarnitines profiles between obese and non-obese individuals.
Article
Food Science & Technology
Inmaculada Criado-Navarro, Maria Asuncion Lopez-Bascon, Carlos Augusto Ledesma-Escobar, Feliciano Priego-Capote
Summary: The study found that using extra-virgin olive oil for deep-frying at high temperatures significantly reduces the content of phenolic compounds, leading to structural changes in these compounds.
ACS FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
