Article
Chemistry, Applied
B. R. Pradeepa, T. M. Vijayakumar, L. S. Dhivya, K. Manikandan
Summary: Psychiatric disorders are a group of mental disorders that manifest as abnormal mental or behavioral habits. Dopamine imbalance plays a major role in many psychiatric disorders. This study evaluated the effects of Piperine, Curcumin, and Capsaicin on dopaminergic activity and compared their inhibition activity on cytochrome P450 3A4 and 2D6 using in-silico methods. The results showed that Piperine had a higher inhibitory activity on CYP 3A4, 2D6 enzymes, and dopamine D2 receptor compared to Curcumin and Capsaicin.
NATURAL PRODUCT RESEARCH
(2023)
Article
Food Science & Technology
Thais Cardoso Merlo, Luciano Molognoni, Rodrigo Barcellos Hoff, Heitor Daguer, Iliani Patinho, Carmen J. Contreras-Castillo
Summary: A novel method was developed for the determination of PAHs in smoked bacon using pressurized liquid extraction and LC-MS/MS, with satisfactory performance evaluated based on various parameters. The method proved to be fast, cheap, efficient, and reliable when applied to real samples, with PAHs levels below the maximum limits suggested by the Commission Regulation.
Article
Dermatology
Yaqi Mao, Ziqian Xu, Jun Song, Yihui Xie, Xingyu Mei, Weimin Shi
Summary: The study found that the mixed preparation of piperine, capsaicin, and curcumin is effective in treating alopecia areata, but it has not been shown to be superior to minoxidil in short-term therapy.
JOURNAL OF COSMETIC DERMATOLOGY
(2022)
Article
Energy & Fuels
Sachin R. Shirsath, Sunil S. Sable, Shashank G. Gaikwad, Parag R. Gogate
Summary: The study focused on the intensified extraction of curcumin from Curcuma aromatica using ultrasound-assisted extraction (UAE) compared to conventional batch extraction, showing that UAE resulted in higher extraction yield in a shorter period of time.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2021)
Article
Biochemistry & Molecular Biology
Patareeya Lasunon, Nipaporn Sengkhamparn
Summary: This study investigated the effects of ultrasound-assisted (UAE), microwave-assisted (MAE), and ultrasound-microwave-assisted (UMAE) methods on pectin extraction from industrial tomato waste. The best extraction conditions were determined based on a fuzzy analytical method, considering pectin yield, galacturonic acid, and lycopene content. The results showed that UAE conditions with pH 1.5 and solid liquid (SL) ratio 1:30 resulted in high pectin yield and lycopene content. MAE conditions with 300 W power for 10 min yielded high pectin yield and galacturonic acid content. Moreover, the combination of UAE and MAE (UMAE) further improved the pectin yield compared to individual methods. However, the FTIR spectra of the obtained pectins showed similar structures regardless of the extraction technique.
Article
Food Science & Technology
Sara Hedayati, Mehrdad Niakousari, Siavash Babajafari, Seyed Mohammad Mazloomi
Summary: This review compared the properties of mucilage extracted from seeds using conventional extraction and ultrasound-assisted extraction, showing that the latter had positive effects such as increasing extraction yield, improving mucilage properties, and reducing impurities. However, the efficiency of ultrasound-assisted extraction in enhancing functional and bioactive properties of seed gums was influenced by various factors, including processing parameters and intrinsic attributes of mucilage.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Review
Acoustics
Arthur Luiz Baiao Dias, Ana Carolina de Aguiar, Mauricio A. Rostagno
Summary: This study provides a comprehensive assessment of high-pressure systems, specifically supercritical fluid extraction and pressurized liquid extraction assisted by ultrasound, as emerging technologies for extracting bioactive compounds from natural products. The extraction mechanisms, applications, and the influence of operational parameters in the process are addressed, along with an analysis of the main challenges for widespread application.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Acoustics
Sooridarsan Krishnan, Noraini Abd Ghani, Noor Fathanah Aminuddin, Khurrum Shehzad Quraishi, Beatrice Luciana Razafindramangarafara, Stephane Baup, Jean-Marc Leveque
Summary: This study investigates the potential of using small amounts of ionic liquids to enhance ultrasound-assisted extraction of lipids content from green microalgae. The findings suggest that the addition of ILs improves ultrasonication by enhancing viscosity and reducing water surface tension, resulting in a more powerful acoustic cavitation process. Additionally, the yield of extracted lipids from green microalgae shows an incremental trend with increasing IL concentration.
ULTRASONICS SONOCHEMISTRY
(2021)
Review
Food Science & Technology
Noman Walayat, Aysun Yurdunuseven-Yildiz, Manoj Kumar, Gulden Goksen, Sebahat Oztekin, Jose Manuel Lorenzo
Summary: Vegetable oils are extracted from oilseeds, fruits, and other parts of plants. The method of oil extraction greatly affects the quality of the final product and the environment. Mechanical pressing and solvent extraction are commonly used methods, but they have disadvantages in terms of product quality and environmental impact. This review explores the use of microwave and ultrasound-assisted extraction in conventional oil extraction processes and discusses their effects on the physicochemical properties and antioxidant properties of the extracted oil.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Acoustics
Yijie Wang, Xiong Xiong, Gangliang Huang
Summary: The extraction, purification, structure, derivatization, and biological activities of maidenhair tree polysaccharides were discussed. Collaborative extraction methods such as ultrasound-assisted extraction and microwave-assisted extraction were used for polysaccharide extraction, with ultrasound-assisted extraction showing higher content and efficiency. The structural characteristics and structure-activity relationship of maidenhair tree polysaccharides were studied to support the further development and utilization of these polysaccharides.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xin Liu, Rui Wang, Changge Wang, Wancheng Li, Yun Huang, Yao Li, Huchuan Wang, Chengjun Peng, Haixia Hu, Bo Wu, Chuanrun Li
Summary: A coupled ultrasonic extraction process enhanced by graphene-oxide-assisted solvent was developed for extracting curcumin from Curcuma longa L. The yield was optimized by investigating extraction temperature, time, ethanol volume fraction, and graphene oxide concentration. The highest extraction yield of 64.9 mg/g was achieved under the optimal parameters, surpassing previous results. This optimized process not only saves production expenses but also provides a safer and cleaner production environment, demonstrating its great potential for application.
SEPARATION SCIENCE AND TECHNOLOGY
(2023)
Article
Acoustics
Su Jin Eom, Tae-Gyu Lim, Hyunjhung Jhun, Nam Hyouck Lee, Min-Cheol Kang, Kyung-Mo Song
Summary: The study developed a yeast extract capable of inhibiting melanoma cells using ultrasound technology, showing that it effectively reduces cell growth and proliferation, as well as tumor volume in mice. Optimal extraction conditions resulted in increased total extraction and 8-glucan yields, suggesting that UAEY may represent an effective anti-skin cancer agent.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Chemistry, Analytical
Marjan Mazrouei Sebdani, Hajar Abbasi
Summary: This study aimed to extract carotenoids from pumpkin using ultrasound and sunflower oil as a green solvent. The optimal extraction conditions were found to be a solid-solvent ratio of 0.08 g/mL, a temperature of 30°C, and an extraction time of 55 min. These conditions resulted in the highest carotenoid content, 8 -carotene, phenolic content, and antioxidant activity.
MICROCHEMICAL JOURNAL
(2023)
Article
Metallurgy & Metallurgical Engineering
Fengzhen Zhang, Huanhuan Zhang, Wei Zhang, Xiuhua Tang, Hua-Jun Shawn Fan
Summary: The process of ultrasound-assisted extraction of vanadium from aqueous phase to organic phase by MAC was investigated. The factors influencing the extraction rate, such as stirring speed, temperature, and ultrasound power, were studied. It was found that increasing the stirring speed and ultrasound power could eliminate diffusion resistance and conform the extraction process to a first-order kinetic model.
Article
Acoustics
Danger Tabio-Garcia, Francisco Paraguay-Delgado, Miguel A. Sanchez-Madrigal, Armando Quintero-Ramos, Jose C. Espinoza-Hicks, Carmen O. Melendez-Pizarro, Martha G. Ruiz-Gutierrez, Eduardo Espitia-Rangel
Summary: This study optimized the ultrasound-assisted extraction of bioactive compounds from Amaranthus hypochondriacus var. Nutrisol using response surface methodology. The results showed that temperature and ultrasonic power densities significantly affected the extraction of betalains, polyphenols, and other bioactive compounds. The optimal extraction conditions were found to be at 41.80 degrees C and 188.84 mW/mL.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Teresa Martinez-Sena, Polina Soluyanova, Carla Guzman, Jose Manuel Valdivielso, Jose Vicente Castell, Ramiro Jover
Article
Biochemistry & Molecular Biology
Isabel Ten-Domenech, Teresa Martinez-Sena, Marta Moreno-Torres, Juan Daniel Sanjuan-Herraez, Jose Castell, Anna Parra-Llorca, Maximo Vento, Guillermo Quintas, Julia Kuligowski
Article
Chemistry, Analytical
A. Sorribes-Soriano, S. Armenta, F. A. Esteve-Turrillas, J. M. Herrero-Martinez
ANALYTICA CHIMICA ACTA
(2020)
Article
Chemistry, Analytical
Aitor Sorribes-Soriano, Josep Verdeguer, Agustin Pastor, Sergio Armenta, Francesc A. Esteve-Turrillas
Summary: A method for determining synthetic cannabinoids in oral fluid samples has been developed using a MEPS-GC-MS procedure, demonstrating high potential for semi-automated, selective, and sensitive detection. The study evaluated five synthetic cannabinoids as model compounds, showing high recoveries and sensitivity, with potential for future application in oral fluid samples.
JOURNAL OF ANALYTICAL TOXICOLOGY
(2021)
Article
Toxicology
Guillermo Quintas, Teresa Martinez-Sena, Isabel Conde, Eugenia Pareja Ibars, Jos Kleinjans, Jose Castell
Summary: DILI, an adverse toxic reaction associated with drug administration, is currently classified based on ALT and ALP values, but lacks accuracy. By integrating metabolomic information, a more accurate evaluation of DILI phenotypes can be achieved.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Toxicology
Laia Tolosa, Teresa Martinez-Sena, Johannes P. Schimming, Erika Moro, Sylvia E. Escher, Bas Ter Braak, Bob van Der Water, M. A. Miranda, Barbara M. A. van Vugt-Lussenburg, Jose Castell
Summary: Phenols are highly toxic chemicals with ambiguous fate in in vitro systems. Cross-contamination was found in high-throughput test systems, but it can be prevented by physicochemical changes and the use of gas-permeable and non-permeable plastic seals. This prevention method allows for a more reliable assessment of phenol-induced toxicity in vitro.
ARCHIVES OF TOXICOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Sergio Armenta, Francesc A. Esteve-Turrillas, Salvador Garrigues, Miguel de la Guardia
Summary: The analysis of biological samples presents challenges due to matrix complexity and low target analyte concentrations, thus different sample treatment methods are used to improve extraction selectivity, sensitivity, and reusability. The combination of microextraction approaches with smart materials provides environmentally friendly strategies for sample preparation, including various materials such as antibodies, molecularly imprinted polymers, and ionic liquids.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Article
Biochemical Research Methods
Asuncion Morales-Noe, Francesc A. Esteve-Turrillas, Sergio Armenta
Summary: Synthetic cannabinoids are a major group of new psychoactive substances with high potency effects, and their metabolism is usually entirely unknown. This study evaluated the metabolism of five third generation synthetic cannabinoids using zebrafish larvae as a model and proposed metabolic pathways for each compound. Zebrafish larvae, with genetic similarity to humans, are a useful tool for identifying the metabolic pathways of psychoactive substances.
DRUG TESTING AND ANALYSIS
(2022)
Article
Chemistry, Analytical
Ariadna Denia, Francesc A. Esteve-Turrillas, Sergio Armenta
Summary: In this study, a GC-IMS analytical procedure was developed for the determination of psychoactive substances in oral fluids. The method showed sensitive and robust signals, with model compounds providing limits of detection ranging from 6 to 15 μg L-1. The proposed technique was proven to be reliable, selective, and sensitive for the analysis of psychoactive substances in oral fluids.
Article
Chemistry, Analytical
Maria D. Maeso-Garcia, Francesc A. Esteve-Turrillas, Jorge Verdu-Andres
Summary: The importance of ventilation in closed workplaces has grown significantly during the COVID-19 pandemic. A new method using a PID to calculate air changes per hour (ACH) in naturally ventilated rooms has been demonstrated as an effective and efficient way to monitor ventilation levels.
Article
Biochemical Research Methods
M. Munoz-Bartual, J. M. Herrero-Martinez, F. A. Esteve-Turrillas
Summary: A fast and simple method for synthesizing paper-immobilized molecularly imprinted polymers (MIPs) using a 405 nm laser pointer was proposed. The paper-MIP device allows the extraction and determination of methamphetamine in oral fluids and urine with high portability and minimal solvent consumption. The method provides a limit of detection of 14 μg L -1 and quantitative recoveries from 81 to 95%.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Biochemical Research Methods
Evan Lesne, Miguel Munoz-Bartual, Francesc A. Esteve-Turrillas
Summary: A fast and simple procedure based on MEPS and LC-MS/MS was developed for quantifying 28 synthetic hallucinogens in oral fluids. The proposed method demonstrated high precision and quantitative recoveries, with limits of detection ranging from 0.09 to 1.22 µg/L. It is suitable for the determination of NBOMe derivatives and other synthetic hallucinogenic substances in oral fluid samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
P. Garcia-Atienza, H. Martinez-Perez-Cejuela, E. F. Simo-Alfonso, J. M. Herrero-Martinez, S. Armenta
Summary: This study developed a liquid chromatography with fluorescence detection (LC-FD) method for analyzing 8 synthetic cannabinoids in oral fluids. The method was validated for linearity, precision, and extraction recoveries, with detection limits as low as 0.7 μg/L and quantification limits of 2.6 μg/L. Supel-Select HLB solid phase extraction cartridges provided quantitative recoveries for the extraction of synthetic cannabinoids in oral fluids.
Article
Food Science & Technology
Alejandro Garcia-Juan, Nuria Leon, Sergio Armenta, Olga Pardo
Summary: This study successfully developed and validated an analytical method for the simultaneous determination of ergot, tropane, and pyrrolizidine alkaloids in cereal-based food. The method showed high recoveries and precision, meeting the validation requirements. Analysis of reference materials further confirmed the reliability of the method. Analysis of actual samples revealed the presence of ergot alkaloids and pyrrolizidine alkaloids in some samples.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
