Article
Food Science & Technology
Wanyi Zhou, Qin Shu, Xinglin Zhang, Qihe Chen
Summary: This study investigated the effects of Lactobacillus brevis on ethyl carbamate (EC) reduction in yellow rice wine fermentation with Saccharomyces cerevisiae, and identified an optimal mixed-culture fermentation method to reduce EC concentration by up to 68.4%. L. brevis not only had a beneficial influence on EC concentration, but also on the hedonic quality of yellow rice wine. However, the coexistence of gallic acid and L. brevis attenuated their inhibitory effect on EC formation.
Article
Food Science & Technology
Shufang Tian, Weizhu Zeng, Jingwen Zhou, Guocheng Du
Summary: This study used high-throughput sequencing technology to investigate the microbial community composition in Huzhou rice wine during fermentation and identified the correlation between urea content and microbial communities. The metabolic profiles of key genes in the arginine and urea pathways were also analyzed. The results provide valuable insights into the metabolism of arginine and urea during rice wine fermentation, contributing to the improvement of rice wine safety.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Joao M. Leca, Vanda Pereira, Andreia Miranda, Jose Luis Vilchez, Jose C. Marques
Summary: The study found that arginine can induce the formation of ethyl carbamate in fortified wines under accelerated aging conditions, even though it has lower reactivity, it can still play a significant role when residual levels are high. Additionally, glucose and fructose were shown to suppress the formation of ethyl carbamate through the urea and citrulline pathways.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
Maksim Yu. Shalamitskiy, Tatiana N. Tanashchuk, Sofia N. Cherviak, Egor A. Vasyagin, Nikolai V. Ravin, Andrey V. Mardanov
Summary: Ethyl carbamate, a probable human carcinogen, is found in fermented foods and alcoholic beverages. This review summarizes its formation mechanisms, impact on human health, and methods used to minimize its content.
Article
Chemistry, Applied
Ying Li, Lezhen Dong, Yahui Liu, Qin Chen, Zufang Wu, Lingyi Liu, Mohamed A. Farag, Lianliang Liu
Summary: The effects of covalent binding of protocatechuic acid (PA) and gallic acid (GA) to lactoferrin (LF) on the structure, functional, and antioxidant properties of the protein conjugate were investigated. The LF-PA/GA conjugates showed altered hydrodynamic diameter and zeta-potential, but their antioxidant activities remained unchanged.
Article
Food Science & Technology
Siyu Xue, Naihui Dong, Kexin Xiong, Hui Guo, Yiwei Dai, Huipeng Liang, Yingxi Chen, Xinping Lin, Beiwei Zhu, Sufang Zhang
Summary: In this study, two Candida ethanolica strains (J1 and J116) capable of directly degrading ethyl carbamate (EC) were isolated and immobilized. These immobilized strains reduced EC concentrations in Chinese Baijiu by 42.27% and 27.91%, respectively. Furthermore, the main flavor substances in Chinese Baijiu were not affected by the presence of these strains, suggesting their potential for the treatment and commercialization of Chinese Baijiu.
Article
Food Science & Technology
Xiaoyun Fei, Yuzhong Yan, Langhong Wang, Zhaohua Huang, Deming Gong, Guowen Zhang
Summary: This study aimed to investigate the effects of gallic acid (GA)/protocatechuic acid (PA) on the structure and function of whey proteins (WP) through covalent binding. Covalent complexes of WP-PA and WP-GA were prepared at different concentrations using the alkaline method. The results showed that PA/GA was cross-linked to WP through covalent bonds, resulting in a slight loosening of the WP structure. The interaction with GA also increased the emulsion stability index and thermal stability of WP, as well as the antioxidant capacity of WP. These findings provide valuable information for enhancing the functional properties of WP and the application of PA/GA-WP covalent complexes in food emulsifiers.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Agriculture, Multidisciplinary
Huajun Zheng, Kai Meng, Jun Liu, Zichen Lin, Qi Peng, Guangfa Xie, Peng Wu, Nabil Ibrahim Elsheery
Summary: This study obtained an acid urea-degrading bacterium Enterobacter sp. R-SYB082 through microbial screening and isolated a new acid urea-degrading enzyme, ureidoglycolate amidohydrolase (UAH), from the strain. UAH was able to degrade ethyl carbamate (EC) directly. Cloning and expression of UAH in Escherichia coli BL21 (DE3) showed that the urea-degrading enzyme activity reached 3560 U L-1, while the urethanase activity reached 2883 U L-1 under optimal fermentation conditions. The enzyme had the dual ability to degrade the substrate urea and the product EC, achieving a removal rate of 90.7% for EC in Chinese rice wine.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Yingxin Ma, Shuangli Guo, Jingxiang Zhang, Yan Xu, Dong Wang
Summary: This study found that urea hydrolysis is the main mechanism of urea consumption during storage of Huangjiu, and established kinetic models for urea consumption and EC formation, determining urea control indicators and EC benchmark limits for Huangjiu. Low-temperature storage can slow down and reduce the production of EC.
Article
Chemistry, Analytical
Long Wu, Yasheng Wang, Shuhong Zhou, Yongheng Zhu, Xiaoqiang Chen
Summary: By developing an electrochemical immunoassay method based on enzyme-induced Cu2+/Cu+ conversion, the sensitivity for detecting ethyl carbamate was improved, combining the advantages of electrochemistry and ELISA, showing good selectivity and high sensitivity in wine samples.
ANALYTICA CHIMICA ACTA
(2021)
Review
Chemistry, Medicinal
Nazia Nazam, Nasimudeen R. Jabir, Iftikhar Ahmad, Saif A. Alharthy, Mohd Shahnawaz Khan, Rashid Ayub, Shams Tabrez
Summary: Cancer is a global health problem that is on the rise, and ovarian cancer is one of the leading causes of mortality worldwide. Current treatments for ovarian cancer have limited effectiveness and come with side effects, recurrence risk, and drug resistance. Therefore, there is a need for alternative, cost-effective, and safer therapeutic strategies.
Review
Food Science & Technology
Huan Deng, Lin Ji, Xiaoyu Han, Tianyang Wu, Bing Han, Chenyu Li, Jicheng Zhan, Weidong Huang, Yilin You
Summary: Ethyl carbamate (EC) is a probable carcinogenic compound commonly found in fermented foods and alcoholic beverages, and there is a need for regulation of EC content in wine due to high detection rates and maximum content. Existing methods for controlling EC in wine include optimizing raw materials and processes, using genetically engineered strains, and enzymatic methods. This review introduces and compares these methods, and proposes two new techniques, the use of different fermentation strains and the addition of phenolic compounds, to regulate EC during wine production. The formation mechanism and analysis methods of EC in wine are also discussed.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Article
Microbiology
Zabdiel Alvarado-Martinez, Zajeba Tabashsum, Arpita Aditya, Grace Suh, Matthew Wall, Katherine Hshieh, Debabrata Biswas
Summary: This study evaluated the potential of phenolic compounds in eliminating Salmonella and modulating the microbiota of complex environments. Results showed that phenolic compounds significantly reduced the quantity of Salmonella and had positive effects on certain beneficial bacteria.
Article
Agriculture, Multidisciplinary
Eva Lopez-Rituerto, Klavs M. Sorensen, Francesco Savorani, Soren B. Engelsen, Alberto Avenoza, Jesus M. Peregrina, Jesus H. Busto
Summary: Proton nuclear magnetic resonance (H-1-NMR) is a quantitative and unbiased analytical technique that can be used to monitor quantitative changes in wine metabolites during the winemaking process. This study demonstrates the potential of NMR as a process analytical technology tool in the wine industry, by monitoring amino acids, organic acids, and polyphenols.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Food Science & Technology
Naihui Dong, Siyu Xue, Hui Guo, Kexin Xiong, Xinping Lin, Huipeng Liang, Chaofan Ji, Zhiguo Huang, Sufang Zhang
Summary: A novel ethyl carbamate hydrolase (ECH) with high specificity to EC was discovered, and immobilization was used to enhance its stability and tolerance. The study also found that immobilized ECH can effectively reduce the concentration of EC in liquor, with minimal impact on flavor substances.
Article
Automation & Control Systems
Yang Gao, Yifei Wu, Xiang Wang, Qingwei Chen
Summary: An adaptive fault-tolerant control scheme is proposed for four-motor servo systems to address the serious impact of actuator failures on control performance. This scheme utilizes characteristic modeling, adaptive sliding mode observer, discrete-time extended state observer, and a fault-tolerant controller based on characteristic model to effectively restrain system error and ensure stability. The effectiveness of the adaptive control scheme and fault tolerance is evaluated through simulation and experiment results.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART I-JOURNAL OF SYSTEMS AND CONTROL ENGINEERING
(2021)
Article
Computer Science, Artificial Intelligence
He Zhang, Qiuhong Chen, Pengbo Ni, Haibo Liang, Min Mao, Jialing Zou
Summary: This paper proposes a method for identifying the lithology of a drilled formation using element and gamma spectrum measurement, as well as establish an intelligent identification model. The field application shows that the accuracy of the proposed method can reach 90.9%, verifying the feasibility of using this approach for intelligent identification of formation lithology during drilling.
NEURAL COMPUTING & APPLICATIONS
(2022)
Article
Hematology
Qiu-Sha Huang, Xiao-Lu Zhu, Qing-Yuan Qu, Xiao Liu, Gao-Chao Zhang, Yan Su, Qi Chen, Feng-Qi Liu, Xue-Yan Sun, Mei-Ying Liang, Yi Liu, Ming Jiang, Hui Liu, Ru Feng, Hong-Xia Yao, Lei Zhang, Shen-Xian Qian, Tong-Hua Yang, Jing-Yu Zhang, Xu-Liang Shen, Lin-Hua Yang, Jian-Da Hu, Ren-Wei Huang, Zhong-Xing Jiang, Jing-Wen Wang, Hong-Yu Zhang, Zhen Xiao, Si-Yan Zhan, Hui-Xin Liu, Ying-Jun Chang, Qian Jiang, Hao Jiang, Jin Lu, Lan-Ping Xu, Xiao-Hong Zhang, Cheng-Hong Yin, Jian-Liu Wang, Xiao-Jun Huang, Xiao-Hui Zhang
Summary: A prediction model for postpartum hemorrhage (PPH) in patients with immune thrombocytopenia (ITP) was developed and validated through a nationwide multicenter retrospective study. The MONITOR model, based on seven risk factors, showed high accuracy in predicting PPH, contributing to more precise clinical care and better health care resource allocation.
AMERICAN JOURNAL OF HEMATOLOGY
(2021)
Article
Cell Biology
Huanjia Gao, Jeremy Bigalke, Enshe Jiang, Yuanyuan Fan, Bojun Chen, Qing-Hui Chen, Zhiying Shan
Summary: The study revealed that TNF alpha can induce inflammatory response in brain neurons and PVN of rats, with Dahl-S rats showing a more significant response to TNF alpha compared to SD rats. This increased inflammatory response in Dahl-S rats may indicate an underlying mechanism for enhanced pressor reactivity to salt intake in the Dahl-S rat model.
CELLULAR AND MOLECULAR NEUROBIOLOGY
(2022)
Article
Chemistry, Inorganic & Nuclear
Abdelmoneim Bakur, Hongyun Lu, Tarig Elshaarani, Dafaallah Albashir, Anas Mohammed, Qihe Chen
Summary: This study introduces a green method for fabricating biocomposites using microbial glycolipids, showing strong antioxidant properties and effectiveness in inhibiting the growth of liver cancer cells.
JOURNAL OF CLUSTER SCIENCE
(2022)
Article
Multidisciplinary Sciences
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Baifeng Zhang, Xiaona Fang, Li Liu, Min Luo, Beilei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Ho-Fun Lee, Ka-On Lam, Anthony Wing-Ip Lo, Zhiwei Chen, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Summary: The authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identified tumor-specific signatures in five stromal clusters of cells that may influence patient survival.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Medicinal
Guanglin Chen, Maricarmen Gonzalez, Ziran Jiang, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen
Summary: (-)-Zampanolide is a unique microtubule stabilizing agent with covalent-binding mechanism and low nanomolar anitproliferative potency towards multi-drug resistant cancer cells. MSAs have a special connection with prostate cancer by inhibiting androgen receptor nuclear translocation.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2021)
Article
Engineering, Electrical & Electronic
Haoran Li, Shengdong Wang, Zhiliang Zhang, Jingfei Zhang, Mengrui Li, Zhanbiao Gu, Xiaoyong Ren, Qianhong Chen
Summary: A digital bidirectional synchronous rectification online calculation control method for 700V high voltage has been proposed, which effectively reduces common mode noise and improves efficiency. Experimental results show that the LLC efficiency in both forward and reverse modes has been enhanced.
IEEE TRANSACTIONS ON POWER ELECTRONICS
(2021)
Article
Architecture
Biao Zhou, Jiazhi Sun, Xukun Sun, Kai Wang, Chen Qingqing, Xuan Wang, Yajun Han
Summary: Chinese historic buildings with wooden structures are prone to fire disasters. The effects of hydrogen fluoride (HF) released during fire suppression on these buildings are unclear. Experimental results show that flame enhancement occurs at the early stage of fire suppression with various types of fire agents.
INTERNATIONAL JOURNAL OF ARCHITECTURAL HERITAGE
(2023)
Article
Biochemical Research Methods
Ping Yu, Xinxin Wang, Jian Ma, Qili Zhang, Qingwei Chen
Summary: This study investigated the chaperone-assisted soluble expression of high molecular weight chitinase chiZJ408 in Escherichia coli BL21 and its optimal conditions for activity. Results showed that introduction of the chaperone GroELS improved the correct folding and solubility of chitinase chiZJ408. Additionally, Mg(2+) and Ca2+ were found to significantly impact the activity of chitinase chiZJ408.
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
(2022)
Article
Biochemical Research Methods
Min He, Jian Ma, Qingwei Chen, Qili Zhang, Ping Yu
Summary: The study successfully enhanced the production of PLP in E. coli by constructing a recombinant strain, and determined the optimal conditions for production, laying a good foundation for the efficient production of PLP.
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
(2022)
Review
Chemistry, Applied
Yixin Wu, Yu Li, Yang Wang, Qian Liu, Qingguo Chen, Minghua Chen
Summary: Developing highly foldable batteries with no safety hazard is crucial for portable, wearable, and implantable electric devices. Solid-state batteries, particularly those based on PVDF electrolytes, show great potential, but also face challenges such as lower ionic conductivity and lack of reactive groups. Recent research has focused on gel polymer electrolytes and all solid polymer electrolytes based on PVDF to address these issues.
JOURNAL OF ENERGY CHEMISTRY
(2022)
Article
Education & Educational Research
Guangtian Zhu, Xiaoling Su, Juan Du, Qingwei Chen, Bolong Xiong, Feng-Kuang Chiang
Summary: The study explored the effects of different scaffolds on students' physics problem solving, with MAPS scaffold showing more effective results. Future research will focus on the application of dynamic figures in physics problem-solving.
INTERACTIVE LEARNING ENVIRONMENTS
(2023)
Article
Computer Science, Information Systems
Xuan Hua, Jungang Han, Chen Zhao, Haipeng Tang, Zhuo He, Qinghui Chen, Shaojie Tang, Jinshan Tang, Weihua Zhou
Summary: This paper presents a novel end-to-end ECG signal classification algorithm using a segmentation strategy and 1D Convolutional Neural Networks (CNN). The proposed method achieves high accuracy in classifying different types of heartbeats, reducing the workload of physicians. Experimental results demonstrate better performance compared to state-of-the-art methods.
MULTIMEDIA SYSTEMS
(2022)
Article
Biotechnology & Applied Microbiology
Runnan Zhou, Siqi Yang, Bo Zhang, Zhaoming Qi, Dawei Xin, Anyu Su, Sinan Li, Peng Cheng, Yunqi Bai, Zhengong Yin, Binshuo Zhang, Yujing Zhao, Ying Zhao, Qingshan Chen, Xiaoxia Wu
Summary: This study developed a set of universal gSSR primers for genetic diversity analysis of three important grain legume resources. Common beans showed the highest genetic diversity while mung beans showed the lowest. Analysis based on genetic relationships and algorithms divided the test resources into different subgroups.
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT
(2021)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
