Hypothalamic lipid-laden astrocytes induce microglia migration and activation

A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system

(2016) Takuya Iizumi et al.   Journal of Neuroinflammation

Melatonin Redox Activity. Its Potential Clinical Applications in Neurodegenerative Disorders

(2015) Elzbieta Miller et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Quercetin reduces obesity-induced hepatosteatosis by enhancing mitochondrial oxidative metabolism via heme oxygenase-1

(2015) Chu-Sook Kim et al.   Nutrition & Metabolism

Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation

(2015) K. C. G. de Git et al.   Obesity Reviews

Hypothalamic inflammation and gliosis in obesity

(2015) Mauricio D. Dorfman et al.   Current Opinion in Endocrinology Diabetes and Obesity

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Fractalkine (CX3CL1) Is Involved in the Early Activation of Hypothalamic Inflammation in Experimental Obesity

(2014) Joseane Morari et al.   DIABETES

Hypothalamic Gliosis Associated With High-Fat Diet Feeding Is Reversible in Mice: A Combined Immunohistochemical and Magnetic Resonance Imaging Study

(2014) Kathryn E. Berkseth et al.   ENDOCRINOLOGY

Obesity and dementia: Adipokines interact with the brain

(2014) Ilse A.C. Arnoldussen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system

(2013) Laura B. Buckman et al.   BRAIN BEHAVIOR AND IMMUNITY

Monocyte chemoattractant protein-1 and the blood–brain barrier

(2013) Yao Yao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Astrocyte-Microglia Cooperation in the Expression of a Pro-Inflammatory Phenotype

(2013) Massimo Barbierato et al.   CNS & Neurological Disorders-Drug Targets

Hormones and diet, but not body weight, control hypothalamic microglial activity

(2013) Yuanqing Gao et al.   GLIA

Blockade of 4-1BB and 4-1BBL Interaction Reduces Obesity-Induced Skeletal Muscle Inflammation

(2013) Ngoc Hoan Le et al.   MEDIATORS OF INFLAMMATION

Hypothalamic Astrocytes in Obesity

(2012) Cristina García-Cáceres et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

4-1BB/4-1BBL Interaction Promotes Obesity-Induced Adipose Inflammation by Triggering Bidirectional Inflammatory Signaling in Adipocytes/Macrophages

(2012) Thai Hien Tu et al.   MEDIATORS OF INFLAMMATION

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Emerging role of glial cells in the control of body weight

(2012) Cristina García-Cáceres et al.   Molecular Metabolism

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Deficiency for Costimulatory Receptor 4-1BB Protects Against Obesity-Induced Inflammation and Metabolic Disorders

(2011) C.-S. Kim et al.   DIABETES

Low-Grade Hypothalamic Inflammation Leads to Defective Thermogenesis, Insulin Resistance, and Impaired Insulin Secretion

(2011) Ana Paula Arruda et al.   ENDOCRINOLOGY

Role of microglia in CNS inflammation

(2011) Manuel B. Graeber et al.   FEBS LETTERS

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Brain Fatty Acid Uptake in Metabolic Syndrome

(2010) A. Karmi et al.   DIABETES

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY