Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation

Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets

(2016) Sandra Heller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis

(2016) Kellie E. Cunningham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation

(2015) Kuei-Wen Chang et al.   Food & Function

GSK3β-dependent inhibition of AMPK potentiates activation of neutrophils and macrophages and enhances severity of acute lung injury

(2014) Dae Won Park et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Innate and adaptive immunity in inflammatory bowel disease

(2013) Alessandra Geremia et al.   AUTOIMMUNITY REVIEWS

EBSeq: an empirical Bayes hierarchical model for inference in RNA-seq experiments

(2013) Ning Leng et al.   BIOINFORMATICS

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

(2013) Amarjargal Dashdorj et al.   BMC Medicine

Molecular mechanism of action of metformin: old or new insights?

(2013) Graham Rena et al.   DIABETOLOGIA

Mitochondrial Gene Polymorphisms That Protect Mice From Colitis

(2013) Florian Bär et al.   GASTROENTEROLOGY

Hallmarks of a new era in mitochondrial biochemistry

(2013) D. J. Pagliarini et al.   GENES & DEVELOPMENT

Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer

(2013) Seong-Joon Koh et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Efficient Repopulation of Genetically Derived Rho Zero Cells with Exogenous Mitochondria

(2013) Sandra Heller et al.   PLoS One

Effect of mtDNA point mutations on cellular bioenergetics

(2012) Joanna Szczepanowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Common alleles that influence autophagy and the risk for inflammatory bowel disease

(2012) Agnès Gardet et al.   CURRENT OPINION IN IMMUNOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Novel role of AMP-activated protein kinase signaling in cigarette smoke induction of IL-8 in human lung epithelial cells and lung inflammation in mice

(2011) Gau-Jun Tang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective role of uncoupling protein-2 against dextran sodium sulfate-induced colitis

(2011) Hongjie Zhang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Mitochondrial control of the NLRP3 inflammasome

(2011) Oliver Kepp et al.   NATURE IMMUNOLOGY

The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1

(2010) Emma Barroso et al.   BIOCHEMICAL PHARMACOLOGY

Novel Anti-Inflammatory Action of 5-Aminoimidazole-4-carboxamide Ribonucleoside with Protective Effect in Dextran Sulfate Sodium-Induced Acute and Chronic Colitis

(2010) A. Bai et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Association of UCP2 −866 G/A polymorphism with chronic inflammatory diseases

(2009) X Yu et al.   GENES AND IMMUNITY

Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohnʼs disease

(2009) Belén Beltrán et al.   INFLAMMATORY BOWEL DISEASES

AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function

(2009) Michael Scharl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation

(2009) Lobke Snoeks et al.   LABORATORY INVESTIGATION

Tumor Suppressor Foxo3a Is Involved in the Regulation of Lipopolysaccharide-Induced Interleukin-8 in Intestinal HT-29 Cells

(2008) L. Snoeks et al.   INFECTION AND IMMUNITY

Tumor Necrosis Factor α Inhibits Oxidative Phosphorylation through Tyrosine Phosphorylation at Subunit I of CytochromecOxidase

(2008) Lobelia Samavati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation of ρ 0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

(2008) Alexandra Kukat et al.   NUCLEIC ACIDS RESEARCH