Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis

PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function

(2015) Ying Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Mitochondria-Derived Reactive Oxygen Species to Reduce Epithelial Barrier Dysfunction and Colitis

(2014) Arthur Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Mucosal Barrier, Bacteria and Inflammatory Bowel Disease: Possibilities for Therapy

(2014) Yvette Merga et al.   DIGESTIVE DISEASES

Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: A novel mechanism of albumin-induced tubulointerstitial inflammation

(2014) Dan Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

(2014) Valerie S. LeBleu et al.   NATURE CELL BIOLOGY

RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway

(2014) Xiaqiong Wang et al.   NATURE IMMUNOLOGY

PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis

(2014) S Baldelli et al.   Cell Death & Disease

Mitochondrial Gene Polymorphisms That Protect Mice From Colitis

(2013) Florian Bär et al.   GASTROENTEROLOGY

Challenges in Designing a National Surveillance Program for Inflammatory Bowel Disease in the United States

(2013) Millie D. Long et al.   INFLAMMATORY BOWEL DISEASES

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Mitochondria and Tumor Progression in Ulcerative Colitis

(2013) Cigdem Himmetoglu Ussakli et al.   JNCI-Journal of the National Cancer Institute

Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis

(2013) L. E. Glover et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extranuclear Localization of SIRT1 and PGC-1α: An Insight into Possible Roles in Diseases Associated with Mitochondrial Dysfunction

(2012) K. Aquilano et al.   CURRENT MOLECULAR MEDICINE

Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence

(2012) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mitochondrial electron transport chain complex dysfunction in the colonic mucosa in ulcerative colitis

(2012) Srikanth Santhanam et al.   INFLAMMATORY BOWEL DISEASES

Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms

(2012) J Gregory Caporaso et al.   ISME Journal

SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

(2012) Hongwei Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

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(2012) Bixi Jian et al.   MOLECULAR MEDICINE

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1α by PRMT1 and SIRT1

(2011) Maira Moreno Garcia et al.   JOURNAL OF PATHOLOGY

Peroxisome proliferator-activated receptor-  coactivator 1-  (PGC1 ) is a metabolic regulator of intestinal epithelial cell fate

(2011) I. D'Errico et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC-1α is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscle

(2010) Lotte Leick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations

(2010) Hsiuchen Chen et al.   CELL

SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

(2010) Michelle Pacholec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory bowel disease in children: current trends

(2010) Gargi Shikhare et al.   JOURNAL OF GASTROENTEROLOGY

SRT1720 Induces Mitochondrial Biogenesis and Rescues Mitochondrial Function after Oxidant Injury in Renal Proximal Tubule Cells

(2010) J. A. Funk et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis

(2010) Karla G. Sifroni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Treatment with SRT1720, a SIRT1 activator, ameliorates fatty liver with reduced expression of lipogenic enzymes in MSG mice

(2009) Yu Yamazaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic Stress Evokes Decreases in Epithelial Barrier Function

(2009) Kimberley Lewis et al.   Annals of the New York Academy of Sciences

Nitric Oxide, Cytochrome C Oxidase, and the Cellular Response to Hypoxia

(2009) Cormac T. Taylor et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection

(2009) Merce Pallas et al.   CURRENT NEUROVASCULAR RESEARCH

Heterogeneity of Mitochondria and Mitochondrial Function within Cells as Another Level of Mitochondrial Complexity

(2009) Andrey Kuznetsov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Mitochondrial Dynamics in Mammalian Health and Disease

(2009) Marc Liesa et al.   PHYSIOLOGICAL REVIEWS

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

(2008) Wendy Rodenburg et al.   BMC GENOMICS

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

Direct Health Care Costs of Crohn's Disease and Ulcerative Colitis in US Children and Adults

(2008) Michael D. Kappelman et al.   GASTROENTEROLOGY