Programming microphysiological systems for children’s health protection

Exposure to the environmental endocrine disruptor TCDD and human reproductive dysfunction: Translating lessons from murine models

(2017) Kaylon L. Bruner-Tran et al.   REPRODUCTIVE TOXICOLOGY

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function

(2016) SY Chang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A microphysiological model of the human placental barrier

(2016) Cassidy Blundell et al.   LAB ON A CHIP

Neural tube morphogenesis in synthetic 3D microenvironments

(2016) Adrian Ranga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational modeling and simulation of genital tubercle development

(2016) Maxwell C.K. Leung et al.   REPRODUCTIVE TOXICOLOGY

Zika virus impairs growth in human neurospheres and brain organoids

(2016) P. P. Garcez et al.   SCIENCE

FutureTox III: Bridges for Translation

(2016) Daland R. Juberg et al.   TOXICOLOGICAL SCIENCES

Phthalate metabolism and kinetics in an in vitro model of testis development

(2016) Sean Harris et al.   TOXICOLOGY IN VITRO

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor

(2015) Jacquelyn A. Brown et al.   Biomicrofluidics

Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research

(2015) Gill Langley et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

(2015) Michael P. Schwartz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stage-specific signaling pathways during murine testis development and spermatogenesis: A pathway-based analysis to quantify developmental dynamics

(2015) Susanna H. Wegner et al.   REPRODUCTIVE TOXICOLOGY

FutureTox II: In vitro Data and In Silico Models for Predictive Toxicology

(2015) Thomas B. Knudsen et al.   TOXICOLOGICAL SCIENCES

Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm

(2015) Ethan S. Lippmann et al.   Stem Cell Reports

Systems Toxicology: From Basic Research to Risk Assessment

(2014) Shana J. Sturla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Of human-on-a-chip and humans: Considerations for creating and using microphysiological systems

(2014) William Slikker   EXPERIMENTAL BIOLOGY AND MEDICINE

The relevance and potential roles of microphysiological systems in biology and medicine

(2014) John P Wikswo   EXPERIMENTAL BIOLOGY AND MEDICINE

Microphysiological modeling of the reproductive tract: A fertile endeavor

(2014) Sharon L Eddie et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Biological and medical applications of a brain-on-a-chip

(2014) David Pamies et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Integrating in vitro organ-specific function with the microcirculation

(2014) Monica L Moya et al.   Current Opinion in Chemical Engineering

Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants

(2013) Shengde Wu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices

(2013) J. Craig Rowlands et al.   TOXICOLOGICAL SCIENCES

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

(2013) Oksana Sirenko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

(2013) Abhinav Bhushan et al.   Stem Cell Research & Therapy

Neurovascular unit on a chip: implications for translational applications

(2013) Donald J Alcendor et al.   Stem Cell Research & Therapy

A Computational Model Predicting Disruption of Blood Vessel Development

(2013) Nicole Kleinstreuer et al.   PLoS Computational Biology

Thick-tissue bioreactor as a platform for long-term organotypic culture and drug delivery

(2012) Dmitry A. Markov et al.   LAB ON A CHIP

Tutorial on agent-based modelling and simulation

(2011) C M Macal et al.   Journal of Simulation

Toxicology for the twenty-first century

(2009) Thomas Hartung   NATURE