Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay

γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9

(2016) Derek T. Bernacki et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach

(2016) Steven M. Bryce et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Updated recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests

(2016) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells

(2015) Heng-Hong Li et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Genotoxicity of flubendazole and its metabolitesin vitroand the impact of a new formulation onin vivoaneugenicity

(2015) David J. Tweats et al.   MUTAGENESIS

Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay

(2015) Jennifer R. Cheung et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The γH2AX Assay for Genotoxic and Nongenotoxic Agents: Comparison of H2AX Phosphorylation with Cell Death Response

(2014) Teodora Nikolova et al.   TOXICOLOGICAL SCIENCES

A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells

(2013) A. Kimura et al.   MUTAGENESIS

Assessment of the in vitro γH2AX assay by High Content Screening as a novel genotoxicity test

(2013) Carolina Garcia-Canton et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A Mode-of-Action Approach for the Identification of Genotoxic Carcinogens

(2013) Lya G. Hernández et al.   PLoS One

Efficient Monitoring of In Vivo Pig-a Gene Mutation and Chromosomal Damage: Summary of 7 Published Studies and Results From 11 New Reference Compounds

(2012) Stephen D. Dertinger et al.   TOXICOLOGICAL SCIENCES

Regulation of brefeldin A-induced ER stress and apoptosis by mitochondrial NADP+-dependent isocitrate dehydrogenase

(2011) Jung Lee Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes

(2011) Stephen D. Dertinger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells

(2011) Sabry M. Attia   JOURNAL OF APPLIED TOXICOLOGY

Genotoxicity screening via the γH2AX by flow assay

(2011) D.J. Smart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The ToxTracker Assay: Novel GFP Reporter Systems that Provide Mechanistic Insight into the Genotoxic Properties of Chemicals

(2011) Giel Hendriks et al.   TOXICOLOGICAL SCIENCES

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

(2010) M. Payton et al.   CANCER RESEARCH

Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure

(2010) A. Rossnerova et al.   MUTAGENESIS

In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models

(2010) M. Kirsch-Volders et al.   MUTAGENESIS

Emodin Triggers DNA Double-Strand Breaks by Stabilizing Topoisomerase II-DNA Cleavage Complexes and by Inhibiting ATP Hydrolysis of Topoisomerase II

(2010) Yan Li et al.   TOXICOLOGICAL SCIENCES

Use of the γH2AX assay for assessing the genotoxicity of polycyclic aromatic hydrocarbons in human cell lines

(2010) M. Audebert et al.   TOXICOLOGY LETTERS

Molecular cytogenetic evaluation of the mechanism of micronuclei formation induced by camptothecin, topotecan, and irinotecan

(2009) Sabry M. Attia et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Literature review on the genotoxicity, reproductive toxicity, and carcinogenicity of ethyl methanesulfonate

(2009) Elmar Gocke et al.   TOXICOLOGY LETTERS

Cytotoxic and genotoxic effects of matrices for cartilage tissue engineering

(2009) Amelie S. Lotz et al.   TOXICOLOGY LETTERS

Improving dose selection and identification of aneugens in the in vitro chromosome aberration test by integration of flow cytometry-based methods

(2008) Paula A. Muehlbauer et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Caffeine Induces Cell Death via Activation of Apoptotic Signal and Inactivation of Survival Signal in Human Osteoblasts

(2008) Pin-Zhen Lu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ECVAM retrospective validation of in vitro micronucleus test (MNT)

(2008) R. Corvi et al.   MUTAGENESIS

Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: A follow-up to an ECVAM workshop

(2008) David Kirkland et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS