Genotoxicity of flubendazole and its metabolitesin vitroand the impact of a new formulation onin vivoaneugenicity

MutAIT: an online genetic toxicology data portal and analysis tools

(2015) Daniele Avancini et al.   MUTAGENESIS

Comparison ofin vitroandin vivoclastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data

(2015) Jeffrey C. Bemis et al.   MUTAGENESIS

IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)

(2015) James T. MacGregor et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk

(2015) James T. MacGregor et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

New approaches to advance the use of genetic toxicology analyses for human health risk assessment

(2015) George E. Johnson et al.   Toxicology Research

Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

(2014) G.E. Johnson et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Shape and steepness of toxicological dose–response relationships of continuous endpoints

(2013) Wout Slob et al.   CRITICAL REVIEWS IN TOXICOLOGY

Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro

(2013) Sibylle Ermler et al.   MUTAGENESIS

A Mode-of-Action Approach for the Identification of Genotoxic Carcinogens

(2013) Lya G. Hernández et al.   PLoS One

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

(2012) B.B. Gollapudi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Can carcinogenic potency be predicted from in vivo genotoxicity data? a meta-analysis of historical data

(2011) Lya G. Hernández et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs

(2011) Charles D Mackenzie et al.   Expert Review of Anti-Infective Therapy

The Geographic Distribution of Loa loa in Africa: Results of Large-Scale Implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA)

(2011) Honorat Gustave Marie Zouré et al.   PLoS Neglected Tropical Diseases

The antihelmintic flubendazole inhibits microtubule function through a mechanism distinct from Vinca alkaloids and displays preclinical activity in leukemia and myeloma

(2010) P. A. Spagnuolo et al.   BLOOD

Potential thresholds for genotoxic effects by micronucleus scoring

(2010) A. Elhajouji et al.   MUTAGENESIS

Lymphatic Filariasis Control in Tanzania: Effect of Repeated Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission

(2010) Paul E. Simonsen et al.   PLoS Neglected Tropical Diseases