Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy

Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

(2016) Johan Medina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

(2016) Valerie N. Babinsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis

(2016) Fadil M Hannan et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Glucagon secretion from pancreatic α-cells

(2016) Linford Briant et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice

(2016) Yoon Sin Oh et al.   PLoS One

Calcimimetic and Calcilytic Drugs: Feats, Flops, and Futures

(2015) E. F. Nemeth et al.   CALCIFIED TISSUE INTERNATIONAL

Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion

(2015) Maria L. Golson et al.   DIABETES

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1)

(2015) Fadil M. Hannan et al.   ENDOCRINOLOGY

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype–phenotype correlations, codon bias and dominant-negative effects

(2015) Fadil M. Hannan et al.   HUMAN MOLECULAR GENETICS

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

(2015) Makoto Shigeto et al.   JOURNAL OF CLINICAL INVESTIGATION

The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon

(2015) Abhishek Aggarwal et al.   Molecular Cancer

The Role of ARX in Human Pancreatic Endocrine Specification

(2015) Blair K. Gage et al.   PLoS One

Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion

(2015) Miles Berger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association Studies of Calcium-Sensing Receptor (CaSR) Polymorphisms with Serum Concentrations of Glucose and Phosphate, and Vascular Calcification in Renal Transplant Recipients

(2015) Valerie N. Babinsky et al.   PLoS One

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion

(2014) Patrik Rorsman et al.   DIABETOLOGIA

Cardiometabolic Phenotyping of Patients With Familial Hypocalcuric Hypercalcemia

(2014) Peter Wolf et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Na+current properties in islet α- and β-cells reflect cell-specificScn3aandScn9aexpression

(2014) Quan Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

(2013) Quan Zhang et al.   Cell Metabolism

TCF7L2 in mouse pancreatic beta cells plays a crucial role in glucose homeostasis by regulating beta cell mass

(2013) Iseki Takamoto et al.   DIABETOLOGIA

An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess

(2013) Liz Bentley et al.   ENDOCRINOLOGY

Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer

(2013) Julia Höbaus et al.   INTERNATIONAL JOURNAL OF CANCER

KATP channels and islet hormone secretion: new insights and controversies

(2013) Frances M. Ashcroft et al.   Nature Reviews Endocrinology

Diabetes Mellitus and the β Cell: The Last Ten Years

(2012) Frances M. Ashcroft et al.   CELL

Proliferation Rates of Multiple Endocrine Neoplasia Type 1 (MEN1)-Associated Tumors

(2012) Gerard V. Walls et al.   ENDOCRINOLOGY

The Effects of Ronacaleret, a Calcium-Sensing Receptor Antagonist, on Bone Mineral Density and Biochemical Markers of Bone Turnover in Postmenopausal Women with Low Bone Mineral Density

(2011) Lorraine A. Fitzpatrick et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

(2010) Yang Z. De Marinis et al.   Cell Metabolism

Glucose-mediated spatial interactions of voltage dependent calcium channels and calcium sensing receptor in insulin producing β-cells

(2010) Jai Parkash   LIFE SCIENCES

Paracrinology of islets and the paracrinopathy of diabetes

(2010) R. H. Unger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

(2009) Bo Ahrén   NATURE REVIEWS DRUG DISCOVERY

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance

(2008) M. Goldsworthy et al.   DIABETES

Voltage-Gated Ion Channels in Human Pancreatic  -Cells: Electrophysiological Characterization and Role in Insulin Secretion

(2008) M. Braun et al.   DIABETES

Whole Berries versus Berry Anthocyanins: Interactions with Dietary Fat Levels in the C57BL/6J Mouse Model of Obesity

(2008) Ronald L. Prior et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY