Wnt Signaling in Cell Motility and Invasion: Drawing Parallels between Development and Cancer

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

(2016) Henner F. Farin et al.   NATURE

Upregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse model

(2015) HAIJI BO et al.   Molecular Medicine Reports

Extracellular microvesicles and invadopodia mediate non-overlapping modes of tumor cell invasion

(2015) Alanna E. Sedgwick et al.   Scientific Reports

Increased expression of ARF GTPases in prostate cancer tissue

(2015) Claire Morgan et al.   SpringerPlus

Melanoma

(2015) Dirk Schadendorf et al.   Nature Reviews Disease Primers

Wnt3a expression is associated with MMP-9 expression in primary tumor and metastatic site in recurrent or stage IV colorectal cancer

(2014) Myung Ah Lee et al.   BMC CANCER

AXIN1 and AXIN2 variants in gastrointestinal cancers

(2014) Serina M. Mazzoni et al.   CANCER LETTERS

The emerging role of exosomes in Wnt secretion and transport

(2014) Liang Zhang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

EphB/ephrinB Signaling in Cell Adhesion and Migration

(2014) Inji Park et al.   MOLECULES AND CELLS

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer

(2014) Paulo Rodrigues et al.   Nature Communications

The role of the non-canonical Wnt–planar cell polarity pathway in neural crest migration

(2013) Roberto Mayor et al.   BIOCHEMICAL JOURNAL

The Wnt/β-catenin pathway in ovarian cancer: A review

(2013) Rebecca C. Arend et al.   GYNECOLOGIC ONCOLOGY

ARF6-Regulated Endocytosis of Growth Factor Receptors Links Cadherin-Based Adhesion to Canonical Wnt Signaling in Epithelia

(2013) O. Pellon-Cardenas et al.   MOLECULAR AND CELLULAR BIOLOGY

Patterning and growth control by membrane-tethered Wingless

(2013) Cyrille Alexandre et al.   NATURE

Wnt Stabilization of  -Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

(2013) S.-E. Kim et al.   SCIENCE

A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

(2013) S. J. Habib et al.   SCIENCE

The Small GTPase ARF6 Stimulates  -Catenin Transcriptional Activity During WNT5A-Mediated Melanoma Invasion and Metastasis

(2013) A. H. Grossmann et al.   Science Signaling

Multiple functions of the noncanonical Wnt pathway

(2013) Eva Gómez-Orte et al.   TRENDS IN GENETICS

The Role of Ryk and Ror Receptor Tyrosine Kinases in Wnt Signal Transduction

(2013) J. Green et al.   Cold Spring Harbor Perspectives in Biology

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Eph/ephrin signalling during development

(2012) R. Klein   DEVELOPMENT

Neural crest delamination and migration: From epithelium-to-mesenchyme transition to collective cell migration

(2012) Eric Theveneau et al.   DEVELOPMENTAL BIOLOGY

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

(2012) C. D'Souza-Schorey et al.   GENES & DEVELOPMENT

Upon Wnt stimulation, Rac1 activation requires Rac1 and Vav2 binding to p120-catenin

(2012) Gabriela Valls et al.   JOURNAL OF CELL SCIENCE

Effects of the miR-143/-145 MicroRNA Cluster on the Colon Cancer Proteome and Transcriptome

(2012) Kerry M. Bauer et al.   JOURNAL OF PROTEOME RESEARCH

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Proteomic Analysis of Microvesicles Released by the Human Prostate Cancer Cell Line PC-3

(2012) Kirsten Sandvig et al.   MOLECULAR & CELLULAR PROTEOMICS

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ADP-ribosylation factors 1 and 6 regulate Wnt/β-catenin signaling via control of LRP6 phosphorylation

(2012) W Kim et al.   ONCOGENE

RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells

(2012) B Li et al.   ONCOGENE

Wnt Proteins

(2012) K. Willert et al.   Cold Spring Harbor Perspectives in Biology

TCF/LEFs and Wnt Signaling in the Nucleus

(2012) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility

(2012) Maki Ishida-Takagishi et al.   Nature Communications

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The planar cell polarity pathway in vertebrate development

(2011) Carolien Wansleeben et al.   DEVELOPMENTAL DYNAMICS

Matrix Metalloproteinase (MMP)-9 Induced by Wnt Signaling Increases the Proliferation and Migration of Embryonic Neural Stem Cells at Low O2Levels

(2011) Christopher A. Ingraham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential expression of canonical and non-canonical Wnt ligands in ameloblastoma

(2011) Chong Huat Siar et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Arf6, RalA, and BIRC5 protein expression in nonsmall cell lung cancer

(2011) A. V. Knizhnik et al.   MOLECULAR BIOLOGY

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

(2011) K. A. Mulligan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult Skeletal Muscle Stem Cell Migration Is Mediated by a Blebbing/Amoeboid Mechanism

(2011) Anthony Otto et al.   REJUVENATION RESEARCH

Microvesicles as mediators of intercellular communication in cancer—the emerging science of cellular ‘debris’

(2011) Tae Hoon Lee et al.   Seminars in Immunopathology

Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2

(2010) Masayuki Kamino et al.   CANCER SCIENCE

Rac and Rho GTPases in cancer cell motility control

(2010) Matteo Parri et al.   Cell Communication and Signaling

The involvement of Eph–Ephrin signaling in tissue separation and convergence during Xenopus gastrulation movements

(2010) Edmond Changkyun Park et al.   DEVELOPMENTAL BIOLOGY

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

(2010) Iwai   INTERNATIONAL JOURNAL OF ONCOLOGY

Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling

(2010) Arthit Chairoungdua et al.   JOURNAL OF CELL BIOLOGY

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

Unregulated ARF6 Activation in Epithelial Cysts Generates Hyperactive Signaling Endosomes and Disrupts Morphogenesis

(2010) Jogender S. Tushir et al.   MOLECULAR BIOLOGY OF THE CELL

Noncanonical Wnt11 Inhibits Hepatocellular Carcinoma Cell Proliferation and Migration

(2010) T. Toyama et al.   MOLECULAR CANCER RESEARCH

Cilia self-organize in response to planar cell polarity and flow

(2010) Wallace F. Marshall   NATURE CELL BIOLOGY

ADP-Ribosylation Factor 6 Regulates Tumorigenic and Invasive Properties In vivo

(2009) V. Muralidharan-Chari et al.   CANCER RESEARCH

Preferential Induction of EphB4 over EphB2 and Its Implication in Colorectal Cancer Progression

(2009) S. R. Kumar et al.   CANCER RESEARCH

Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless

(2009) Ceren Korkut et al.   CELL

ARF6-Regulated Shedding of Tumor Cell-Derived Plasma Membrane Microvesicles

(2009) Vandhana Muralidharan-Chari et al.   CURRENT BIOLOGY

Rho-regulated Myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation

(2009) D. C. Weiser et al.   DEVELOPMENT

A study on the interactions between heparan sulfate proteoglycans and Wnt proteins

(2009) Christophe Fuerer et al.   DEVELOPMENTAL DYNAMICS

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy

(2009) Y. Wang   MOLECULAR CANCER THERAPEUTICS

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of the non-canonical Dvl–Rac1–JNK pathway by Frizzled homologue 10 in human synovial sarcoma

(2009) C Fukukawa et al.   ONCOGENE

Mammalian Wnt3a is Released on Lipoprotein Particles

(2009) Sylvia Neumann et al.   TRAFFIC

Noncanonical Wnt Signaling in Tumor Progression and Metastasis

(2009) Jason R. Jessen   Zebrafish

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

WNT5A Expression Increases during Melanoma Progression and Correlates with Outcome

(2008) P. D. Da Forno et al.   CLINICAL CANCER RESEARCH

Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA

(2008) H. K. Matthews et al.   DEVELOPMENT

Wnt signalling in development and disease. Max Delbrück Center for Molecular Medicine meeting on Wnt Signaling in Development and Disease

(2008) Christophe Fuerer et al.   EMBO REPORTS

Alternative Wnt Signaling Is Initiated by Distinct Receptors

(2008) R. van Amerongen et al.   Science Signaling

The first five years of the Wnt targetome

(2007) Annica Vlad et al.   CELLULAR SIGNALLING