Microglial CX3CR1 promotes adult neurogenesis by inhibiting Sirt 1/p65 signaling independent of CX3CL1

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

(2016) Sabine Hellwig et al.   BRAIN BEHAVIOR AND IMMUNITY

Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice

(2016) XIN-MIN DING et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

(2015) T. Goldmann et al.   EMBO JOURNAL

Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol

(2015) Duanfang Cao et al.   GENES & DEVELOPMENT

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy

(2015) Jérome Chal et al.   NATURE BIOTECHNOLOGY

Microglia Plasticity During Health and Disease: An Immunological Perspective

(2015) Anat Shemer et al.   TRENDS IN IMMUNOLOGY

Defective microglial development in the hippocampus of Cx3cr1 deficient mice

(2015) Francesca Pagani et al.   Frontiers in Cellular Neuroscience

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release

(2015) Robert Nisticò et al.   Scientific Reports

Microglia and their CX3CR1 signaling are involved in hippocampal- but not olfactory bulb-related memory and neurogenesis

(2014) Ronen Reshef et al.   BRAIN BEHAVIOR AND IMMUNITY

p63 and p73 coordinate p53 function to determine the balance between survival, cell death and senescence in adult neural precursor cells

(2014) M P Fatt et al.   CELL DEATH AND DIFFERENTIATION

Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination

(2014) C. G. Fulmer et al.   JOURNAL OF NEUROSCIENCE

NF-κB signaling modulates radiation-induced microglial activation

(2014) JUN XUE et al.   ONCOLOGY REPORTS

Age-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrus

(2013) Michael J. Darcy et al.   HIPPOCAMPUS

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

Mapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractography

(2013) L.-A. Harsan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol Inhibits the Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis

(2012) Hee Ra Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

In vivo structure/function and expression analysis of the CX3C chemokine fractalkine

(2011) K.-W. Kim et al.   BLOOD

IκB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-κB in the central nervous system

(2011) Jenni Raasch et al.   BRAIN

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

(2011) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

(2011) A. Mildner et al.   JOURNAL OF NEUROSCIENCE

Cytosolic RIG-I–like helicases act as negative regulators of sterile inflammation in the CNS

(2011) Angela Dann et al.   NATURE NEUROSCIENCE

Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice

(2011) Rakesh Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

CX3CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment

(2011) Laura Maggi   Frontiers in Cellular Neuroscience

Eotaxin-3/CC Chemokine Ligand 26 Is a Functional Ligand for CX3CR1

(2010) T. Nakayama et al.   JOURNAL OF IMMUNOLOGY

CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-  Phagocytosis

(2010) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

In vivo diffusion tensor magnetic resonance imaging and fiber tracking of the mouse brain

(2010) Laura-Adela Harsan et al.   NMR IN BIOMEDICINE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Fractalkine and CX3CR1 regulate hippocampal neurogenesis in adult and aged rats

(2009) Adam D. Bachstetter et al.   NEUROBIOLOGY OF AGING

NEW evidences for fractalkine/CX3CL1 involved in substantia nigral microglial activation and behavioral changes in a rat model of Parkinson's disease

(2009) Sun Shan et al.   NEUROBIOLOGY OF AGING

IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress

(2008) J. W. Koo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA