RIG-I activation induces the release of extracellular vesicles with antitumor activity

Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency

(2016) F. Zhao et al.   CANCER RESEARCH

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Association of the FAM46A Gene VNTRs and BAG6 rs3117582 SNP with Non Small Cell Lung Cancer (NSCLC) in Croatian and Norwegian Populations

(2015) Godfrey Essien Etokebe et al.   PLoS One

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC

(2015) Benjamin Besse et al.   OncoImmunology

Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways

(2014) Mirjam C. Boelens et al.   CELL

RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells

(2014) P Duewell et al.   CELL DEATH AND DIFFERENTIATION

Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice

(2014) Xiaoyu Gu et al.   INTERNATIONAL JOURNAL OF CANCER

Human Tumor-Derived Exosomes Down-Modulate NKG2D Expression

(2014) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Outsmart tumor exosomes to steal the cancer initiating cell its niche

(2014) Florian Thuma et al.   SEMINARS IN CANCER BIOLOGY

Role of Exosomes Released by Dendritic Cells and/or by Tumor Targets: Regulation of NK Cell Plasticity

(2014) Katrin S. Reiners et al.   Frontiers in Immunology

Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

(2013) K. S. Reiners et al.   BLOOD

BAG-6, a jack of all trades in health and disease

(2013) Janina Binici et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Soluble Fragment of the Tumor Antigen BCL2-associated Athanogene 6 (BAG-6) Is Essential and Sufficient for Inhibition of NKp30 Receptor-dependent Cytotoxicity of Natural Killer Cells

(2013) Janina Binici et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the Cytosolic Innate Immune Receptors RIG-I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma

(2013) Martin Glas et al.   STEM CELLS

Exosomes as nucleic acid nanocarriers

(2012) Jasper G. van den Boorn et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumor cell-derived exosomes: A message in a bottle

(2012) Pedram Kharaziha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Short-Range Exosomal Transfer of Viral RNA from Infected Cells to Plasmacytoid Dendritic Cells Triggers Innate Immunity

(2012) Marlène Dreux et al.   Cell Host & Microbe

Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responsesin Vitro

(2012) Li-Hong Lv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

(2012) Chiara Corrado et al.   PLoS One

BAT3 Regulates Mycobacterium tuberculosis Protein ESAT-6-Mediated Apoptosis of Macrophages

(2012) Ajay Grover et al.   PLoS One

Identifying mRNA, MicroRNA and Protein Profiles of Melanoma Exosomes

(2012) Deyi Xiao et al.   PLoS One

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine

(2011) T. Chen et al.   JOURNAL OF IMMUNOLOGY

Natural Killer Cell Activation Secondary to Innate Pattern Sensing

(2011) Tsukasa Seya et al.   Journal of Innate Immunity

The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts

(2011) Héctor Peinado et al.   SEMINARS IN CANCER BIOLOGY

Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

(2010) S. Viaud et al.   CANCER RESEARCH

Stress for maintaining memory: HSP70 as a mobile messenger for innate and adaptive immunity

(2010) Taoyong Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Exosomes derived from IL-12-anchored renal cancer cells increase induction of specific antitumor response in vitro: A novel vaccine for renal cell carcinoma

(2009) Wu   INTERNATIONAL JOURNAL OF ONCOLOGY

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells

(2009) Robert Besch et al.   JOURNAL OF CLINICAL INVESTIGATION

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Accessing the therapeutic potential of immunostimulatory nucleic acids

(2008) Winfried Barchet et al.   CURRENT OPINION IN IMMUNOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Dendritic Cells Release HLA-B-Associated Transcript-3 Positive Exosomes to Regulate Natural Killer Function

(2008) Venkateswara Rao Simhadri et al.   PLoS One