RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Therapeutic Efficacy of Bifunctional siRNA Combining TGF- 1 Silencing with RIG-I Activation in Pancreatic Cancer

(2013) J. Ellermeier et al.   CANCER RESEARCH

Danger signalling during cancer cell death: origins, plasticity and regulation

(2013) A D Garg et al.   CELL DEATH AND DIFFERENTIATION

Role of Immune Cells and Immune-Based Therapies in Pancreatitis and Pancreatic Ductal Adenocarcinoma

(2013) Lei Zheng et al.   GASTROENTEROLOGY

Multifunctional antitumor molecule 5′-triphosphate siRNA combining glutaminase silencing and RIG-I activation

(2013) Gang Meng et al.   INTERNATIONAL JOURNAL OF CANCER

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Development of antigen cross-presentation capacity in dendritic cells

(2012) Christiane Dresch et al.   TRENDS IN IMMUNOLOGY

Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13

(2011) Rachel F. Gabitass et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CpG Blocks Immunosuppression by Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2011) C. Zoglmeier et al.   CLINICAL CANCER RESEARCH

Sensing of viral nucleic acids by RIG-I: From translocation to translation

(2011) Andreas Schmidt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells

(2011) Kirsten Kübler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Innate and adaptive immune responses to cell death

(2011) Kenneth L. Rock et al.   IMMUNOLOGICAL REVIEWS

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

(2011) Yuting Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Critical Role for Granzymes in Antigen Cross-Presentation through Regulating Phagocytosis of Killed Tumor Cells

(2011) S. Hoves et al.   JOURNAL OF IMMUNOLOGY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

Pancreatoduodenectomy for Ductal Adenocarcinoma

(2010) Javairiah Fatima   ARCHIVES OF SURGERY

Targeted Activation of RNA Helicase Retinoic Acid-Inducible Gene-I Induces Proimmunogenic Apoptosis of Human Ovarian Cancer Cells

(2010) K. Kubler et al.   CANCER RESEARCH

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma

(2010) Collin Jacobs et al.   INTERNATIONAL JOURNAL OF CANCER

APC Activation by IFN-  Decreases Regulatory T Cell and Enhances Th Cell Functions

(2010) L. Pace et al.   JOURNAL OF IMMUNOLOGY

Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells

(2009) Damià Tormo et al.   CANCER CELL

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE

HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression

(2009) James F Curtin et al.   PLOS MEDICINE

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE